Publications by authors named "Alessandro D Uboldi"

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Serological and molecular detection of Toxoplasma gondii in naturally infected red foxes (Vulpes vulpes) from Victoria, Australia.
Leonardo Brustenga, K L D Tharaka D Liyanage, Panayiotis Loukopoulos, Megan Fisher, Jessica Haining, Alessandro D Uboldi

Parasitol Res· December 2025

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A pre-existing chronic Toxoplasma gondii infection promotes epileptogenesis and neuropathology in a mouse model of mesial temporal lobe epilepsy.
Tamara L Baker, David K Wright, Peravina Thergarajan, Alessandro D Uboldi, Anh Vo

Brain Behav Immun· August 2025

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Differentiation of into latent forms is linked to central carbon metabolism and requires a GID/CTLH-type E3 ubiquitin ligase.
Alessandro D Uboldi, Sachin Khurana, Amalie A Jaywickrama, Sai Prasanna Lekkala-Lethakula, Amber Simonpietri

bioRxiv· July 2025

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Seroprevalence and risk factors for Toxoplasma gondii exposure in Australian feral and stray cats using an in-house modified agglutination test.
K L D Tharaka D Liyanage, Jemima Amery-Gale, Alessandro D Uboldi, Katherine Adriaanse, Simon M Firestone

Vet Parasitol· December 2024

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A pre-existing Toxoplasma gondii infection exacerbates the pathophysiological response and extent of brain damage after traumatic brain injury in mice.
Tamara L Baker, David K Wright, Alessandro D Uboldi, Christopher J Tonkin, Anh Vo

J Neuroinflammation· January 2024

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Pre-existing infection increases susceptibility to pentylenetetrazol-induced seizures independent of traumatic brain injury in mice.
Tamara L Baker, Alessandro D Uboldi, Christopher J Tonkin, David K Wright, Anh Vo

Front Mol Neurosci· January 2023

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Transcriptional modification of host cells harboring Toxoplasma gondii bradyzoites prevents IFN gamma-mediated cell death.
Simona Seizova, Ushma Ruparel, Alexandra L Garnham, Stefanie M Bader, Alessandro D Uboldi

Cell Host Microbe· February 2022

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Depletion of a Toxoplasma porin leads to defects in mitochondrial morphology and contacts with the endoplasmic reticulum.
Natalia Mallo, Jana Ovciarikova, Erica S Martins-Duarte, Stephan C Baehr, Marco Biddau, Alessandro D Uboldi

J Cell Sci· October 2021

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Environmental sensing and regulation of motility in Toxoplasma.
Alessandro D Uboldi, Mary-Louise Wilde, Stefanie M Bader, Christopher J Tonkin

Mol Microbiol· May 2021

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Metabolomic Analysis of Toxoplasma gondii Tachyzoites.
Elizabeth F B King, Simon A Cobbold, Alessandro D Uboldi, Christopher J Tonkin, Malcolm J McConville

Methods Mol Biol· January 2021

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An apically located hybrid guanylate cyclase-ATPase is critical for the initiation of Ca signaling and motility in .
Luning Yang, Alessandro D Uboldi, Simona Seizova, Mary-Louise Wilde, Michael J Coffey

J Biol Chem· May 2019

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Protein -fucosyltransferase 2-mediated -glycosylation of the adhesin MIC2 is dispensable for tachyzoite infection.
Sachin Khurana, Michael J Coffey, Alan John, Alessandro D Uboldi, My-Hang Huynh

J Biol Chem· February 2019

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Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii.
Alessandro D Uboldi, Mary-Louise Wilde, Emi A McRae, Rebecca J Stewart, Laura F Dagley

PLoS Biol· September 2018

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Development of a Novel CD4 TCR Transgenic Line That Reveals a Dominant Role for CD8 Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria.
Daniel Fernandez-Ruiz, Lei Shong Lau, Nazanin Ghazanfari, Claerwen M Jones, Wei Yi Ng, Alessandro D Uboldi

J Immunol· December 2017

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A forward genetic screen identifies a negative regulator of rapid Ca-dependent cell egress (MS1) in the intracellular parasite .
James M McCoy, Rebecca J Stewart, Alessandro D Uboldi, Dongdi Li, Jan Schröder

J Biol Chem· May 2017

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Merozoite Antigens of Plasmodium falciparum Elicit Strain-Transcending Opsonizing Immunity.
Danika L Hill, Danny W Wilson, Natalia G Sampaio, Emily M Eriksson, Victoria Ryg-Cornejo, Alessandro D Uboldi

Infect Immun· August 2016

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Multiple Plasmodium falciparum Merozoite Surface Protein 1 Complexes Mediate Merozoite Binding to Human Erythrocytes.
Clara S Lin, Alessandro D Uboldi, Christian Epp, Hermann Bujard, Takafumi Tsuboi

J Biol Chem· April 2016

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Regulation of Starch Stores by a Ca(2+)-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii.
Alessandro D Uboldi, James M McCoy, Martin Blume, Motti Gerlic, David J P Ferguson

Cell Host Microbe· December 2015

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An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell.
Michael J Coffey, Brad E Sleebs, Alessandro D Uboldi, Alexandra Garnham, Magdalena Franco

Elife· November 2015

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The merozoite surface protein 1 complex is a platform for binding to human erythrocytes by Plasmodium falciparum.
Clara S Lin, Alessandro D Uboldi, Danushka Marapana, Peter E Czabotar, Christian Epp

J Biol Chem· September 2014

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Modulation of PF10_0355 (MSPDBL2) alters Plasmodium falciparum response to antimalarial drugs.
Daria Van Tyne, Alessandro D Uboldi, Julie Healer, Alan F Cowman, Dyann F Wirth

Antimicrob Agents Chemother· July 2013

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Insights into Duffy binding-like domains through the crystal structure and function of the merozoite surface protein MSPDBL2 from Plasmodium falciparum.
Anthony N Hodder, Peter E Czabotar, Alessandro D Uboldi, Oliver B Clarke, Clara S Lin

J Biol Chem· September 2012

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Structural and functional association of Trypanosoma brucei MIX protein with cytochrome c oxidase complex.
Alena Zíková, Aswini K Panigrahi, Alessandro D Uboldi, Rachel A Dalley, Emanuela Handman

Eukaryot Cell· November 2008

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Fishing for anti-leishmania drugs: principles and problems.
Emanuela Handman, Lukasz Kedzierski, Alessandro D Uboldi, James W Goding

Adv Exp Med Biol· April 2008

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A mitochondrial protein affects cell morphology, mitochondrial segregation and virulence in Leishmania.
Alessandro D Uboldi, Franziska B Lueder, Peter Walsh, Timothy Spurck, Geoffrey I McFadden

Int J Parasitol· December 2006

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