Publications by authors named "Alessandro Fatica"

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Deregulation and delocalization of the mA demethylase FTO and aberrant mA levels in ccRCC tissue samples.
Claudia Tito, Paolo Rosa, Veronica Sorrentino, Martina Magnanti, Angelica Innocenti, Alessandro Fatica

Histol Histopathol· November 2025

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Off-Target Inhibition of Human Dihydroorotate Dehydrogenase (DHODH) Highlights Challenges in the Development of Fat Mass and Obesity-Associated Protein (FTO) Inhibitors.
Marco Tarullo, Guillermo Fernandez Rodriguez, Alessia Iaiza, Sara Venezia, Alberto Macone, Alessandro Fatica

ACS Pharmacol Transl Sci· December 2024

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MYC upstream region orchestrates resistance to PI3K inhibitors in cancer cells through FOXO3a-mediated autophagic adaptation.
Rosa Bordone, Devon Michael Ivy, Rodrigo D'Amico, Martina Barba, Miriam Gaggianesi, Alessandro Fatica

Oncogene· November 2024

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RNA sequestration in P-bodies sustains myeloid leukaemia.
Srikanth Kodali, Ludovica Proietti, Gemma Valcarcel, Anna V López-Rubio, Patrizia Pessina, Alessandro Fatica

Nat Cell Biol· October 2024

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N-methyladenosine (mA) RNA modification in chronic myeloid leukemia: unveiling a novel therapeutic target.
Guillermo Fernandez Rodriguez, Marco Tarullo, Alessandro Fatica

Cell Mol Life Sci· July 2024

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WTAP and mA-modified circRNAs modulation during stress response in acute myeloid leukemia progenitor cells.
Alessia Iaiza, Gilla Mazzanti, Frauke Goeman, Bianca Cesaro, Clelia Cortile, Alessandro Fatica

Cell Mol Life Sci· June 2024

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Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3.
Bianca Cesaro, Alessia Iaiza, Fabio Piscopo, Marco Tarullo, Eleonora Cesari, Alessandro Fatica

Cancer Commun (Lond)· February 2024

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circPVT1 and PVT1/AKT3 show a role in cell proliferation, apoptosis, and tumor subtype-definition in small cell lung cancer.
Doron Tolomeo, Debora Traversa, Santina Venuto, Karoline K Ebbesen, Juan L García Rodríguez, Alessandro Fatica

Genes Chromosomes Cancer· July 2023

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Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.
Sonia Coni, Rosa Bordone, Devon Michael Ivy, Zuleyha Nihan Yurtsever, Laura Di Magno, Alessandro Fatica

Cancer Lett· April 2023

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The Emerging Role of RNA in Diseases and Cancers.
Alessandro Fatica

Int J Mol Sci· April 2023

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Regulation of Gene Expression by m6Am RNA Modification.
Bianca Cesaro, Marco Tarullo, Alessandro Fatica

Int J Mol Sci· January 2023

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Multiple Roles of m6A RNA Modification in Translational Regulation in Cancer.
Guillermo Fernandez Rodriguez, Bianca Cesaro, Alessandro Fatica

Int J Mol Sci· August 2022

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MALAT1-dependent hsa_circ_0076611 regulates translation rate in triple-negative breast cancer.
Chiara Turco, Gabriella Esposito, Alessia Iaiza, Frauke Goeman, Anna Benedetti, Alessandro Fatica

Commun Biol· June 2022

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Long Non-Coding RNAs in the Cell Fate Determination of Neoplastic Thymic Epithelial Cells.
Alessia Iaiza, Claudia Tito, Federica Ganci, Andrea Sacconi, Enzo Gallo, Alessandro Fatica

Front Immunol· May 2022

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Translational control of polyamine metabolism by CNBP is required for locomotor function.
Sonia Coni, Federica A Falconio, Marta Marzullo, Marzia Munafò, Benedetta Zuliani, Alessandro Fatica

Elife· September 2021

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METTL3-dependent MALAT1 delocalization drives c-Myc induction in thymic epithelial tumors.
Alessia Iaiza, Claudia Tito, Zaira Ianniello, Federica Ganci, Valentina Laquintana, Alessandro Fatica

Clin Epigenetics· September 2021

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New insight into the catalytic -dependent and -independent roles of METTL3 in sustaining aberrant translation in chronic myeloid leukemia.
Zaira Ianniello, Melissa Sorci, Lavinia Ceci Ginistrelli, Alessia Iaiza, Marcella Marchioni, Alessandro Fatica

Cell Death Dis· September 2021

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Regulation of Ribosome Function by RNA Modifications in Hematopoietic Development and Leukemia: It Is Not Only a Matter of mA.
Francesco Fazi, Alessandro Fatica

Int J Mol Sci· April 2021

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ADAR1 is a new target of METTL3 and plays a pro-oncogenic role in glioblastoma by an editing-independent mechanism.
Valentina Tassinari, Valeriana Cesarini, Sara Tomaselli, Zaira Ianniello, Domenico Alessandro Silvestris, Alessandro Fatica

Genome Biol· January 2021

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Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation.
Sonia Coni, Silvia Maria Serrao, Zuleyha Nihan Yurtsever, Laura Di Magno, Rosa Bordone, Alessandro Fatica

Cell Death Dis· December 2020

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LINC00174 is a novel prognostic factor in thymic epithelial tumors involved in cell migration and lipid metabolism.
Claudia Tito, Federica Ganci, Andrea Sacconi, Silvia Masciarelli, Giulia Fontemaggi, Alessandro Fatica

Cell Death Dis· November 2020

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Modulation of circRNA Metabolism by mA Modification.
Gaia Di Timoteo, Dario Dattilo, Alvaro Centrón-Broco, Alessio Colantoni, Marco Guarnacci, Alessandro Fatica

Cell Rep· May 2020

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Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD+ AML.
Silvia Masciarelli, Ernestina Capuano, Tiziana Ottone, Mariadomenica Divona, Serena Lavorgna, Alessandro Fatica

Blood Adv· December 2019

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Interplay Between -Methyladenosine (mA) and Non-coding RNAs in Cell Development and Cancer.
Francesco Fazi, Alessandro Fatica

Front Cell Dev Biol· June 2019

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N-Methyladenosine (mA): A Promising New Molecular Target in Acute Myeloid Leukemia.
Zaira Ianniello, Alessandro Paiardini, Alessandro Fatica

Front Oncol· April 2019

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