Publications by authors named "Alex Agelidis"

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Triple-Negative Breast Cancer on the Rise: Breakthroughs and Beyond [Response to Letter].
Alex Agelidis, Anna Ter-Zakarian, Mohammed Jaloudi

Breast Cancer (Dove Med Press)· October 2025

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Male Breast Cancer: Evaluating the Current Landscape of Diagnosis and Treatment.
Anna Ter-Zakarian, Alex Agelidis, Mohammed Jaloudi

Breast Cancer (Dove Med Press)· July 2025

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Triple-Negative Breast Cancer on the Rise: Breakthroughs and Beyond.
Alex Agelidis, Anna Ter-Zakarian, Mohammed Jaloudi

Breast Cancer (Dove Med Press)· June 2025

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Pathophysiology of reinfection by exogenous HSV-1 is driven by heparanase dysfunction.
Rahul K Suryawanshi, Chandrashekhar D Patil, Alex Agelidis, Raghuram Koganti, Tejabhiram Yadavalli

Sci Adv· April 2023

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Intrinsic Antiviral Activity of Optineurin Prevents Hyperproliferation of a Primary Herpes Simplex Virus Type 2 Infection.
Chandrashekhar D Patil, Rahul Suryawanshi, Joshua Ames, Raghuram Koganti, Alex Agelidis

J Immunol· January 2022

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Heparanase-Induced Activation of AKT Stabilizes β-Catenin and Modulates Wnt/β-Catenin Signaling during Herpes Simplex Virus 1 Infection.
Lulia Koujah, Krishnaraju Madavaraju, Alex M Agelidis, Chandrashekhar D Patil, Deepak Shukla

mBio· December 2021

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mTORC2 confers neuroprotection and potentiates immunity during virus infection.
Rahul K Suryawanshi, Chandrashekhar D Patil, Alex Agelidis, Raghuram Koganti, Joshua M Ames

Nat Commun· October 2021

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Entry receptor bias in evolutionarily distant HSV-1 clinical strains drives divergent ocular and nervous system pathologies.
Lulia Koujah, Mowafak Allaham, Chandrashekhar D Patil, Joshua M Ames, Rahul K Suryawanshi, Alex Agelidis

Ocul Surf· July 2021

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Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival.
Alex Agelidis, Benjamin A Turturice, Rahul K Suryawanshi, Tejabhiram Yadavalli, Dinesh Jaishankar

JCI Insight· April 2021

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Dysregulation of Cell Signaling by SARS-CoV-2.
Rahul K Suryawanshi, Raghuram Koganti, Alex Agelidis, Chandrashekhar D Patil, Deepak Shukla

Trends Microbiol· March 2021

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Dissociation of DNA damage sensing by endoglycosidase HPSE.
Alex Agelidis, Rahul K Suryawanshi, Chandrashekhar D Patil, Anaamika Campeau, David J Gonzalez

iScience· March 2021

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Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing.
Tejabhiram Yadavalli, Rahul Suryawanshi, Raghuram Koganti, James Hopkins, Joshua Ames, Alex Agelidis

Sci Adv· December 2020

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An Intra-Vaginal Zinc Oxide Tetrapod Nanoparticles (ZOTEN) and Genital Herpesvirus Cocktail Can Provide a Novel Platform for Live Virus Vaccine.
Alex Agelidis, Lulia Koujah, Rahul Suryawanshi, Tejabhiram Yadavalli, Yogendra Kumar Mishra

Front Immunol· September 2020

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Heparanase, Heparan Sulfate and Viral Infection.
Alex Agelidis, Deepak Shukla

Adv Exp Med Biol· July 2020

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Bacterial Pigment Prodigiosin Demonstrates a Unique Antiherpesvirus Activity That Is Mediated through Inhibition of Prosurvival Signal Transducers.
Rahul K Suryawanshi, Lulia Koujah, Chandrashekhar D Patil, Joshua M Ames, Alex Agelidis

J Virol· June 2020

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Heparanase-Regulated Syndecan-1 Shedding Facilitates Herpes Simplex Virus 1 Egress.
Satvik Hadigal, Raghuram Koganti, Tejabhiram Yadavalli, Alex Agelidis, Rahul Suryawanshi

J Virol· February 2020

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Drug-encapsulated carbon (DECON): A novel platform for enhanced drug delivery.
Tejabhiram Yadavalli, Joshua Ames, Alex Agelidis, Rahul Suryawanshi, Dinesh Jaishankar

Sci Adv· August 2019

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Pathogenesis of herpes simplex keratitis: The host cell response and ocular surface sequelae to infection and inflammation.
Ann-Marie Lobo, Alex M Agelidis, Deepak Shukla

Ocul Surf· January 2019

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Host Enzymes Heparanase and Cathepsin L Promote Herpes Simplex Virus 2 Release from Cells.
James Hopkins, Tejabhiram Yadavalli, Alex M Agelidis, Deepak Shukla

J Virol· December 2018

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An off-target effect of BX795 blocks herpes simplex virus type 1 infection of the eye.
Dinesh Jaishankar, Abraam M Yakoub, Tejabhiram Yadavalli, Alex Agelidis, Neel Thakkar

Sci Transl Med· February 2018

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Targeting Herpes Simplex Virus-1 gD by a DNA Aptamer Can Be an Effective New Strategy to Curb Viral Infection.
Tejabhiram Yadavalli, Alex Agelidis, Dinesh Jaishankar, Kyle Mangano, Neel Thakkar

Mol Ther Nucleic Acids· December 2017

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Viral Activation of Heparanase Drives Pathogenesis of Herpes Simplex Virus-1.
Alex M Agelidis, Satvik R Hadigal, Dinesh Jaishankar, Deepak Shukla

Cell Rep· July 2017

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Cultured corneas show dendritic spread and restrict herpes simplex virus infection that is not observed with cultured corneal cells.
Neel Thakkar, Dinesh Jaishankar, Alex Agelidis, Tejabhiram Yadavalli, Kyle Mangano

Sci Rep· February 2017

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Cell entry mechanisms of HSV: what we have learned in recent years.
Alex M Agelidis, Deepak Shukla

Future Virol· October 2015

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Erratum: The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis.
Michio Onizawa, Shigeru Oshima, Ulf Schulze-Topphoff, Juan A Oses-Prieto, Timothy Lu, Alex Agelidis

Nat Immunol· July 2015

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