Publications by authors named "Alex C Lam"

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Blockade of orexin receptors with Almorexant reduces cardiorespiratory responses evoked from the hypothalamus but not baro- or chemoreceptor reflex responses.
Kamon Iigaya, Jouji Horiuchi, Lachlan M McDowall, Alex C B Lam, Yusuf Sediqi

Am J Physiol Regul Integr Comp Physiol· November 2012

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Rapid and robust association mapping of expression quantitative trait loci.
Alex C Lam, Michael Schouten, Yurii S Aulchenko, Chris S Haley, Dirk-Jan de Koning

BMC Proc· December 2009

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A combined strategy for quantitative trait loci detection by genome-wide association.
Alex C Lam, Joseph Powell, Wen-Hua Wei, Dirk-Jan de Koning, Chris S Haley

BMC Proc· February 2009

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Optimal design of genetic studies of gene expression with two-color microarrays in outbred crosses.
Alex C Lam, Jingyuan Fu, Ritsert C Jansen, Chris S Haley, Dirk-Jan de Koning

Genetics· November 2008

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Multiple testing in the genomics era: findings from Genetic Analysis Workshop 15, Group 15.
Lisa J Martin, Jessica G Woo, Christy L Avery, Huann-Sheng Chen, Kari E North, Alex C Lam

Genet Epidemiol· April 2008

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Interaction analysis of the CBLB and CTLA4 genes in type 1 diabetes.
Felicity Payne, Jason D Cooper, Neil M Walker, Alex C Lam, Luc J Smink

J Leukoc Biol· March 2007

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Discovery, linkage disequilibrium and association analyses of polymorphisms of the immune complement inhibitor, decay-accelerating factor gene (DAF/CD55) in type 1 diabetes.
Hidenori Taniguchi, Christopher E Lowe, Jason D Cooper, Deborah J Smyth, Rebecca Bailey, Alex C Lam

BMC Genet· April 2006

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Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases.
Deborah J Smyth, Joanna M M Howson, Felicity Payne, Lisa M Maier, Rebecca Bailey, Alex C Lam

BMC Med Genet· March 2006

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Polymorphism discovery and association analyses of the interferon genes in type 1 diabetes.
Gerard A J Morris, Christopher E Lowe, Jason D Cooper, Felicity Payne, Adrian Vella, Alex C Lam

BMC Genet· February 2006

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Population structure, differential bias and genomic control in a large-scale, case-control association study.
David G Clayton, Neil M Walker, Deborah J Smyth, Rebecca Pask, Jason D Cooper, Alex C Lam

Nat Genet· November 2005

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No evidence for association of the TATA-box binding protein glutamine repeat sequence or the flanking chromosome 6q27 region with type 1 diabetes.
Felicity Payne, Deborah J Smyth, Rebecca Pask, Jason D Cooper, Jennifer Masters, Alex C Lam

Biochem Biophys Res Commun· June 2005

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Assessing the validity of the association between the SUMO4 M55V variant and risk of type 1 diabetes.
Deborah J Smyth, Joanna M M Howson, Christopher E Lowe, Neil M Walker, Alex C Lam

Nat Genet· February 2005

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T1DBase, a community web-based resource for type 1 diabetes research.
Luc J Smink, Erin M Helton, Barry C Healy, Christopher C Cavnor, Alex C Lam, Daisy Flamez

Nucleic Acids Res· January 2005

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Association analysis of the lymphocyte-specific protein tyrosine kinase (LCK) gene in type 1 diabetes.
John S Hulme, Bryan J Barratt, Rebecca C J Twells, Jason D Cooper, Chris E Lowe, Alex C Lam

Diabetes· September 2004

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Comparative high-resolution analysis of linkage disequilibrium and tag single nucleotide polymorphisms between populations in the vitamin D receptor gene.
Sergey Nejentsev, Lisa Godfrey, Hywel Snook, Helen Rance, Sarah Nutland, Alex C Lam

Hum Mol Genet· August 2004

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Investigating the utility of combining phi29 whole genome amplification and highly multiplexed single nucleotide polymorphism BeadArray genotyping.
Rebecca Pask, Helen E Rance, Bryan J Barratt, Sarah Nutland, Deborah J Smyth, Alex C Lam

BMC Biotechnol· July 2004

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Haplotype tag single nucleotide polymorphism analysis of the human orthologues of the rat type 1 diabetes genes Ian4 (Lyp/Iddm1) and Cblb.
Felicity Payne, Deborah J Smyth, Rebecca Pask, Bryan J Barratt, Jason D Cooper, Alex C Lam

Diabetes· February 2004

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Development of an integrated genome informatics, data management and workflow infrastructure: a toolbox for the study of complex disease genetics.
Oliver S Burren, Barry C Healy, Alex C Lam, Helen Schuilenburg, Geoffrey E Dolman

Hum Genomics· January 2004

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Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease.
Hironori Ueda, Joanna M M Howson, Laura Esposito, Joanne Heward, Hywel Snook, Alex C Lam

Nature· May 2003

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