Publications by authors named "Alex Eccleston"

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Omics with active learning optimizes phenotypic screens.
Alex Eccleston

Nat Rev Drug Discov· January 2026

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Lectin-based bispecific targets tumour-associated glycans.
Alex Eccleston

Nat Rev Drug Discov· December 2025

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Rebalancing cardiolipin biosynthesis to treat cardiomyopathy.
Alex Eccleston

Nat Rev Drug Discov· November 2025

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Epigenetic inhibitor silences KRAS-driven oncogenes.
Alex Eccleston

Nat Rev Drug Discov· October 2025

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Broader horizons for cereblon glue degraders.
Alex Eccleston

Nat Rev Drug Discov· September 2025

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A neonatal window for in vivo gene therapy in haematopoietic stem cells.
Alex Eccleston

Nat Rev Drug Discov· August 2025

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Hinge modifier approach opens door to drugging HECT E3 ligases.
Alex Eccleston

Nat Rev Drug Discov· June 2025

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Cannabinoid targets hidden pocket for safer pain relief.
Alex Eccleston

Nat Rev Drug Discov· May 2025

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Genetics opens new route to degrader discovery.
Alex Eccleston

Nat Rev Drug Discov· April 2025

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Peptide blocks phase separation and oncogenic transcription.
Alex Eccleston

Nat Rev Drug Discov· March 2025

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Lipid nanoparticle ferries therapeutic mRNA to the placenta.
Alex Eccleston

Nat Rev Drug Discov· February 2025

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Covalent inhibitor engages oncogenic AKT kinase.
Alex Eccleston

Nat Rev Drug Discov· January 2025

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Bivalent molecules unmute silenced genes.
Alex Eccleston

Nat Rev Drug Discov· December 2024

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Agonist antibody lowers blood pressure.
Alex Eccleston

Nat Rev Drug Discov· November 2024

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Degrading cell-free DNA to prevent recurrent stroke.
Alex Eccleston

Nat Rev Drug Discov· October 2024

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Anti-IL-11 antibody shows anti-ageing properties.
Alex Eccleston

Nat Rev Drug Discov· September 2024

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Non-antibiotic drug network reveals new leads for antibiotics.
Alex Eccleston

Nat Rev Drug Discov· May 2024

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Suppressing tumour T cells with a histone demethylase inhibitor.
Alex Eccleston

Nat Rev Drug Discov· April 2024

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Macrocyclic peptides thwart Gram-negative bacteria.
Alex Eccleston

Nat Rev Drug Discov· March 2024

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Stalled molecular motor inhibits tumour growth.
Alex Eccleston

Nat Rev Drug Discov· February 2024

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PROTAC in clinic for autoimmune skin disease.
Alex Eccleston

Nat Rev Drug Discov· January 2024

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Phosphatase inhibitor drives anticancer immune responses.
Alex Eccleston

Nat Rev Drug Discov· December 2023

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Rewired proteostasis in KRAS inhibitor resistance.
Alex Eccleston

Nat Rev Drug Discov· November 2023

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Clipping cell-surface mucins in cancer by targeted degradation.
Alex Eccleston

Nat Rev Drug Discov· October 2023

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Peptide vaccine turns up the heat in ALK-positive cancers.
Alex Eccleston

Nat Rev Drug Discov· September 2023

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