Publications by authors named "Alex Franzusoff"

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Non-viral precision T cell receptor replacement for personalized cell therapy.
Susan P Foy, Kyle Jacoby, Daniela A Bota, Theresa Hunter, Zheng Pan, Alex Franzusoff

Nature· March 2023

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Neoantigen-targeted CD8 T cell responses with PD-1 blockade therapy.
Cristina Puig-Saus, Barbara Sennino, Songming Peng, Clifford L Wang, Zheng Pan, Alex Franzusoff

Nature· March 2023

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Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice.
Susan P Foy, Barbara Sennino, Tracy dela Cruz, Joseph J Cote, Evan J Gordon, Alex Franzusoff

PLoS One· July 2016

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Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells.
Susan P Foy, Stefanie J Mandl, Tracy dela Cruz, Joseph J Cote, Evan J Gordon, Alex Franzusoff

Cancer Immunol Immunother· May 2016

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Elucidating immunologic mechanisms of PROSTVAC cancer immunotherapy.
Stefanie J Mandl, Ryan B Rountree, Tracy B Dela Cruz, Susan P Foy, Joseph J Cote, Alex Franzusoff

J Immunother Cancer· October 2014

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Mutation-specific control of BCR-ABL T315I positive leukemia with a recombinant yeast-based therapeutic vaccine in a murine model.
Melanie R Bui, Victoria Hodson, Tom King, Derek Leopold, Shaodong Dai, Alex Franzusoff

Vaccine· August 2010

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Concurrent vaccination with two distinct vaccine platforms targeting the same antigen generates phenotypically and functionally distinct T-cell populations.
Amanda L Boehm, Jack Higgins, Alex Franzusoff, Jeffrey Schlom, James W Hodge

Cancer Immunol Immunother· March 2010

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Human dendritic cell maturation and activation by a heat-killed recombinant yeast (Saccharomyces cerevisiae) vector encoding carcinoembryonic antigen.
Cinzia Remondo, Vittore Cereda, Sven Mostböck, Helen Sabzevari, Alex Franzusoff

Vaccine· February 2009

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Vaccination with a recombinant Saccharomyces cerevisiae expressing a tumor antigen breaks immune tolerance and elicits therapeutic antitumor responses.
Elizabeth K Wansley, Mala Chakraborty, Kenneth W Hance, Michael B Bernstein, Amanda L Boehm, Alex Franzusoff

Clin Cancer Res· July 2008

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Recombinant Saccharomyces cerevisiae (yeast-CEA) as a potent activator of murine dendritic cells.
Michael B Bernstein, Mala Chakraborty, Elizabeth K Wansley, Zhimin Guo, Alex Franzusoff

Vaccine· January 2008

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Generation of a prophylactic melanoma vaccine using whole recombinant yeast expressing MART-1.
Helge Riemann, Joe Takao, Yiqun G Shellman, Wirt A Hines, Carl K Edwards, Alex Franzusoff

Exp Dermatol· October 2007

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Whole recombinant yeast-based immunotherapy induces potent T cell responses targeting HCV NS3 and Core proteins.
Aurelia A Haller, Georg M Lauer, Thomas H King, Charles Kemmler, Valerie Fiolkoski, Alex Franzusoff

Vaccine· February 2007

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TGF-beta2 inhibition augments the effect of tumor vaccine and improves the survival of animals with pre-established brain tumors.
Yang Liu, Qing Wang, B K Kleinschmidt-DeMasters, Alex Franzusoff, Ka-yun Ng

J Neurooncol· January 2007

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Yeasts encoding tumour antigens in cancer immunotherapy.
Alex Franzusoff, Richard C Duke, Thomas H King, Yingnian Lu, Timothy C Rodell

Expert Opin Biol Ther· April 2005

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Mutation-selective tumor remission with Ras-targeted, whole yeast-based immunotherapy.
Yingnian Lu, Donald Bellgrau, Lori D Dwyer-Nield, Alvin M Malkinson, Richard C Duke, Alex Franzusoff

Cancer Res· August 2004

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Fas ligand-dependent suppression of autoimmunity via recruitment and subsequent termination of activated T cells.
Jaime F Modiano, Juan Sun, Julie Lang, Guido Vacano, David Patterson, Alex Franzusoff

Clin Immunol· July 2004

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Epidermal growth factor receptor mediates silibinin-induced cytotoxicity in a rat glioma cell line.
Lin Qi, Rana P Singh, Yingnian Lu, Rajesh Agarwal, Gail S Harrison, Alex Franzusoff

Cancer Biol Ther· March 2004

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Cell surface expression of the HIV-1 envelope glycoproteins is directed from intracellular CTLA-4-containing regulated secretory granules.
Luis R Miranda, Brian C Schaefer, Abraham Kupfer, Zixin Hu, Alex Franzusoff

Proc Natl Acad Sci U S A· June 2002

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Furin proteolytically processes the heparin-binding region of extracellular superoxide dismutase.
Russell P Bowler, Mike Nicks, Dorte Aa Olsen, Ida B Thøgersen, Zuzana Valnickova, Alex Franzusoff

J Biol Chem· May 2002

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