Publications by authors named "Alex Harwig"

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HIV co-opts a cellular antiviral mechanism, activation of stress kinase PKR by its RNA, to enable splicing of rev/tat mRNA.
Lise Sarah Namer, Alex Harwig, Stephan P Heynen, Atze T Das, Ben Berkhout

Cell Biosci· February 2023

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RNA Polymerase Clamp Movement Aids Dissociation from DNA but Is Not Required for RNA Release at Intrinsic Terminators.
Michael J Bellecourt, Ananya Ray-Soni, Alex Harwig, Rachel Anne Mooney, Robert Landick

J Mol Biol· February 2019

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Mutation of nucleotides around the +1 position of type 3 polymerase III promoters: The effect on transcriptional activity and start site usage.
Zongliang Gao, Alex Harwig, Ben Berkhout, Elena Herrera-Carrillo

Transcription· March 2018

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Influence of the loop size and nucleotide composition on AgoshRNA biogenesis and activity.
Elena Herrera-Carrillo, Alex Harwig, Ben Berkhout

RNA Biol· November 2017

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Analysis of AgoshRNA maturation and loading into Ago2.
Alex Harwig, Zita Kruize, Zhenhuang Yang, Tobias Restle, Ben Berkhout

PLoS One· October 2017

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The Battle of RNA Synthesis: Virus versus Host.
Alex Harwig, Robert Landick, Ben Berkhout

Viruses· October 2017

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The influence of the 5΄-terminal nucleotide on AgoshRNA activity and biogenesis: importance of the polymerase III transcription initiation site.
Elena Herrera-Carrillo, Zong-Liang Gao, Alex Harwig, Matthias T Heemskerk, Ben Berkhout

Nucleic Acids Res· April 2017

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Tat-dependent production of an HIV-1 TAR-encoded miRNA-like small RNA.
Alex Harwig, Aldo Jongejan, Antoine H C van Kampen, Ben Berkhout, Atze T Das

Nucleic Acids Res· May 2016

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Toward optimization of AgoshRNA molecules that use a non-canonical RNAi pathway: variations in the top and bottom base pairs.
Elena Herrera-Carrillo, Alex Harwig, Ben Berkhout

RNA Biol· January 2016

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Construction of Nef-positive doxycycline-dependent HIV-1 variants using bicistronic expression elements.
Yme U van der Velden, Wendy Kleibeuker, Alex Harwig, Bep Klaver, Esther Siteur-van Rijnstra

Virology· January 2016

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HIV-1 transcriptional silencing caused by TRIM22 inhibition of Sp1 binding to the viral promoter.
Filippo Turrini, Sara Marelli, Anna Kajaste-Rudnitski, Marina Lusic, Carine Van Lint, Alex Harwig

Retrovirology· December 2015

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Mechanistic insights on the Dicer-independent AGO2-mediated processing of AgoshRNAs.
Ying Poi Liu, Margarete Karg, Alex Harwig, Elena Herrera-Carrillo, Aldo Jongejan

RNA Biol· November 2015

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Deep Sequence Analysis of AgoshRNA Processing Reveals 3' A Addition and Trimming.
Alex Harwig, Elena Herrera-Carrillo, Aldo Jongejan, Antonius Hubertus van Kampen, Ben Berkhout

Mol Ther Nucleic Acids· July 2015

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HIV-1 RNAs: sense and antisense, large mRNAs and small siRNAs and miRNAs.
Alex Harwig, Atze T Das, Ben Berkhout

Curr Opin HIV AIDS· March 2015

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Probing the shRNA characteristics that hinder Dicer recognition and consequently allow Ago-mediated processing and AgoshRNA activity.
Elena Herrera-Carrillo, Alex Harwig, Ying Poi Liu, Ben Berkhout

RNA· September 2014

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Retroviral microRNAs.
Alex Harwig, Atze T Das, Ben Berkhout

Curr Opin Virol· August 2014

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Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII.
Alexandre Wagschal, Emilie Rousset, Poornima Basavarajaiah, Xavier Contreras, Alex Harwig

Cell· September 2012

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Opening of the TAR hairpin in the HIV-1 genome causes aberrant RNA dimerization and packaging.
Atze T Das, Martine M Vrolijk, Alex Harwig, Ben Berkhout

Retrovirology· July 2012

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The HIV-1 Tat protein has a versatile role in activating viral transcription.
Atze T Das, Alex Harwig, Ben Berkhout

J Virol· September 2011

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Destabilization of the TAR hairpin leads to extension of the polyA hairpin and inhibition of HIV-1 polyadenylation.
Martine M Vrolijk, Alex Harwig, Ben Berkhout, Atze T Das

Retrovirology· February 2009

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Destabilization of the TAR hairpin affects the structure and function of the HIV-1 leader RNA.
Martine M Vrolijk, Marcel Ooms, Alex Harwig, Atze T Das, Ben Berkhout

Nucleic Acids Res· August 2008

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Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution.
Atze T Das, Bep Klaver, Mireille Centlivre, Alex Harwig, Marcel Ooms

Retrovirology· June 2008

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Construction of a doxycycline-dependent simian immunodeficiency virus reveals a nontranscriptional function of tat in viral replication.
Atze T Das, Bep Klaver, Alex Harwig, Monique Vink, Marcel Ooms

J Virol· October 2007

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The TAR hairpin of human immunodeficiency virus type 1 can be deleted when not required for Tat-mediated activation of transcription.
Atze T Das, Alex Harwig, Martine M Vrolijk, Ben Berkhout

J Virol· July 2007

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