Publications by authors named "Alex Kleinpeter"

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Author Correction: HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly.
Nadine Renner, Alex Kleinpeter, Donna L Mallery, Anna Albecka, K M Rifat Faysal

Nat Struct Mol Biol· September 2025

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Structural basis for HIV-1 capsid adaption to a deficiency in IP6 packaging.
Yanan Zhu, Alex B Kleinpeter, Juan S Rey, Juan Shen, Yao Shen

Nat Commun· September 2025

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Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir.
Lorenzo Briganti, Arun S Annamalai, Stephanie M Bester, Guochao Wei, Jonathan R Andino-Moncada, Alex B Kleinpeter

mBio· May 2025

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The central pore of HIV-1 capsomers promotes sustained stability of the viral capsid.
Alex B Kleinpeter, Donna L Mallery, Anna Albecka, Ryan C Burdick, Nadine Renner

bioRxiv· May 2025

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Structural basis for HIV-1 capsid adaption to rescue IP6-packaging deficiency.
Yanan Zhu, Alex B Kleinpeter, Juan S Rey, Juan Shen, Yao Shen

bioRxiv· February 2025

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Structural and Mechanistic Bases for Resistance of the M66I Capsid Variant to Lenacapavir.
Lorenzo Briganti, Arun S Annamalai, Stephanie M Bester, Guochao Wei, Jonathan R Andino-Moncada, Alex B Kleinpeter

bioRxiv· November 2024

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HIV-1 adapts to lost IP6 coordination through second-site mutations that restore conical capsid assembly.
Alex Kleinpeter, Donna L Mallery, Nadine Renner, Anna Albecka, J Ole Klarhof

Nat Commun· September 2024

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Structural Investigations of Interactions between the Influenza a Virus NS1 and Host Cellular Proteins.
Morgan E Blake, Alex B Kleinpeter, Alexander S Jureka, Chad M Petit

Viruses· October 2023

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The Effect of Inositol Hexakisphosphate on HIV-1 Particle Production and Infectivity can be Modulated by Mutations that Affect the Stability of the Immature Gag Lattice.
Alex B Kleinpeter, Yanan Zhu, Donna L Mallery, Sherimay D Ablan, Long Chen

J Mol Biol· June 2023

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HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly.
Nadine Renner, Alex Kleinpeter, Donna L Mallery, Anna Albecka, K M Rifat Faysal

Nat Struct Mol Biol· March 2023

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Structural basis of HIV-1 maturation inhibitor binding and activity.
Sucharita Sarkar, Kaneil K Zadrozny, Roman Zadorozhnyi, Ryan W Russell, Caitlin M Quinn, Alex Kleinpeter

Nat Commun· March 2023

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Enhanced Transmissibility and Decreased Virulence of HIV-1 CRF07_BC May Explain Its Rapid Expansion in China.
Zetao Cheng, Huanchang Yan, Qingmei Li, Sherimay D Ablan, Alex Kleinpeter

Microbiol Spectr· August 2022

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CryoET structures of immature HIV Gag reveal six-helix bundle.
Luiza Mendonça, Dapeng Sun, Jiying Ning, Jiwei Liu, Abhay Kotecha, Alex B Kleinpeter

Commun Biol· April 2021

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A stable immature lattice packages IP for HIV capsid maturation.
Donna L Mallery, Alex B Kleinpeter, Nadine Renner, K M Rifat Faysal, Mariia Novikova

Sci Adv· March 2021

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How to package the RNA of HIV-1.
Alex Kleinpeter, Eric O Freed

Elife· November 2020

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HIV-1 Maturation: Lessons Learned from Inhibitors.
Alex B Kleinpeter, Eric O Freed

Viruses· August 2020

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The influenza NS1 protein modulates RIG-I activation via a strain-specific direct interaction with the second CARD of RIG-I.
Alexander S Jureka, Alex B Kleinpeter, Jennifer L Tipper, Kevin S Harrod, Chad M Petit

J Biol Chem· January 2020

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Cellular IP Levels Limit HIV Production while Viruses that Cannot Efficiently Package IP Are Attenuated for Infection and Replication.
Donna L Mallery, K M Rifat Faysal, Alex Kleinpeter, Miranda S C Wilson, Marina Vaysburd

Cell Rep· December 2019

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Structural analyses reveal the mechanism of inhibition of influenza virus NS1 by two antiviral compounds.
Alex B Kleinpeter, Alexander S Jureka, Sally M Falahat, Todd J Green, Chad M Petit

J Biol Chem· September 2018

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Structural Basis for a Novel Interaction between the NS1 Protein Derived from the 1918 Influenza Virus and RIG-I.
Alexander S Jureka, Alex B Kleinpeter, Gabriel Cornilescu, Claudia C Cornilescu, Chad M Petit

Structure· November 2015

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