Publications by authors named "Alex Mitsialis"

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Mouse radial spoke 3 is a metabolic and regulatory hub in cilia.
Yanhe Zhao, Kangkang Song, Amirrasoul Tavakoli, Long Gui, Angeles Fernandez-Gonzalez, S Alex Mitsialis

Nat Struct Mol Biol· August 2025

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The cryo-EM structure of mouse radial spoke 3 reveals a unique metabolic and regulatory hub in cilia.
Yanhe Zhao, Kangkang Song, Amirrasoul Tavakoli, Long Gui, Angeles Fernandez-Gonzalez, S Alex Mitsialis

bioRxiv· May 2025

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Immunoregulatory Macrophages Modify Local Pulmonary Immunity and Ameliorate Hypoxic Pulmonary Hypertension.
Angeles Fernandez-Gonzalez, Amit Mukhia, Janhavi Nadkarni, Gareth R Willis, Monica Reis, S Alex Mitsialis

Arterioscler Thromb Vasc Biol· December 2024

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Photoreceptors inhibit pathological retinal angiogenesis through transcriptional regulation of Adam17 via c-Fos.
Xudong Wang, Tianxi Wang, Satoshi Kaneko, Emil Kriukov, Enton Lam, S Alex Mitsialis

Angiogenesis· August 2024

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Mesenchymal stromal cell extracellular vesicles improve lung development in mechanically ventilated preterm lambs.
Kurt H Albertine, Andrew Rebentisch, Elaine Dawson, Jakob Van Boerum, Emily Major, S Alex Mitsialis

Am J Physiol Lung Cell Mol Physiol· June 2024

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SOCS3 regulates pathological retinal angiogenesis through modulating SPP1 expression in microglia and macrophages.
Tianxi Wang, Satoshi Kaneko, Emil Kriukov, David Alvarez, Enton Lam, S Alex Mitsialis

Mol Ther· May 2024

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Immunoregulatory macrophages modify local pulmonary immunity and ameliorate hypoxic-pulmonary hypertension.
Angeles Fernandez-Gonzalez, Amit Mukhia, Janhavi Nadkarni, Gareth R Willis, Monica Reis, S Alex Mitsialis

bioRxiv· August 2023

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Harnessing the therapeutic potential of the stem cell secretome in neonatal diseases.
Stephanie Tung, Eleni Delavogia, Angeles Fernandez-Gonzalez, S Alex Mitsialis, Stella Kourembanas

Semin Perinatol· April 2023

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Mesenchymal Stromal/Stem Cell Extracellular Vesicles and Perinatal Injury: One Formula for Many Diseases.
Eleni Delavogia, Dimitrios P Ntentakis, John A Cortinas, Angeles Fernandez-Gonzalez, S Alex Mitsialis

Stem Cells· November 2022

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Antenatal mesenchymal stromal cell extracellular vesicle treatment preserves lung development in a model of bronchopulmonary dysplasia due to chorioamnionitis.
Alison N Abele, Elizabeth S Taglauer, Maricar Almeda, Noah Wilson, Abigail Abikoye, S Alex Mitsialis

Am J Physiol Lung Cell Mol Physiol· February 2022

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Mesenchymal stromal cell-derived syndecan-2 regulates the immune response during sepsis to foster bacterial clearance and resolution of inflammation.
Junwen Han, Yuanyuan Shi, Gareth Willis, Jewel Imani, Min-Young Kwon, S Alex Mitsialis

FEBS J· January 2022

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Antenatal Mesenchymal Stromal Cell Extracellular Vesicle Therapy Prevents Preeclamptic Lung Injury in Mice.
Elizabeth S Taglauer, Angeles Fernandez-Gonzalez, Gareth R Willis, Monica Reis, Vincent Yeung, S Alex Mitsialis

Am J Respir Cell Mol Biol· January 2022

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Extracellular Vesicles Protect the Neonatal Lung from Hyperoxic Injury through the Epigenetic and Transcriptomic Reprogramming of Myeloid Cells.
Gareth R Willis, Monica Reis, Ali Hashemi Gheinani, Angeles Fernandez-Gonzalez, Elizabeth S Taglauer, S Alex Mitsialis

Am J Respir Crit Care Med· December 2021

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Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia.
Monica Reis, Gareth R Willis, Angeles Fernandez-Gonzalez, Vincent Yeung, Elizabeth Taglauer, S Alex Mitsialis

Front Immunol· September 2021

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Intratracheal transplantation of trophoblast stem cells attenuates acute lung injury in mice.
Junwen Han, Gu Li, Minmin Hou, Julie Ng, Min-Young Kwon, S Alex Mitsialis

Stem Cell Res Ther· August 2021

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Therapeutic Effects of Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Oxygen-Induced Multi-Organ Disease: A Developmental Perspective.
Angeles Fernandez-Gonzalez, Gareth R Willis, Vincent Yeung, Monica Reis, Xianlan Liu, S Alex Mitsialis

Front Cell Dev Biol· March 2021

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Mesenchymal stromal cell-derived extracellular vesicle therapy prevents preeclamptic physiology through intrauterine immunomodulation†.
Elizabeth S Taglauer, Angeles Fernandez-Gonzalez, Gareth R Willis, Monica Reis, Vincent Yeung, S Alex Mitsialis

Biol Reprod· February 2021

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International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19.
Verena Börger, Daniel J Weiss, Johnathon D Anderson, Francesc E Borràs, Benedetta Bussolati, S Alex Mitsialis

Cytotherapy· September 2020

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Mesenchymal stromal cell-derived small extracellular vesicles restore lung architecture and improve exercise capacity in a model of neonatal hyperoxia-induced lung injury.
Gareth R Willis, Angeles Fernandez-Gonzalez, Monica Reis, Vincent Yeung, Xianlan Liu, S Alex Mitsialis

J Extracell Vesicles· July 2020

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The Unsettling Ambiguity of Therapeutic Extracellular Vesicles from Mesenchymal Stromal Cells.
S Alex Mitsialis

Am J Respir Cell Mol Biol· May 2020

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Heme oxygenase-1 dampens the macrophage sterile inflammasome response and regulates its components in the hypoxic lung.
Sally H Vitali, Angeles Fernandez-Gonzalez, Janhavi Nadkarni, April Kwong, Chase Rose, S Alex Mitsialis

Am J Physiol Lung Cell Mol Physiol· January 2020

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Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes.
Nahal Mansouri, Gareth R Willis, Angeles Fernandez-Gonzalez, Monica Reis, Sina Nassiri, S Alex Mitsialis

JCI Insight· November 2019

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Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications.
Kenneth W Witwer, Bas W M Van Balkom, Stefania Bruno, Andre Choo, Massimo Dominici, S Alex Mitsialis

J Extracell Vesicles· April 2019

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Corrigendum: Homozygous missense mutation L673P in adenylate kinase 7 (AK7) leads to primary male infertility and multiple morphological anomalies of the flagella but not to primary ciliary dyskinesia.
Patrick Lorès, Charles Coutton, Elma El Khouri, Laurence Stouvenel, Maëlle Givelet, Alex Mitsialis

Hum Mol Genet· March 2019

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Macrophage Immunomodulation: The Gatekeeper for Mesenchymal Stem Cell Derived-Exosomes in Pulmonary Arterial Hypertension?
Gareth R Willis, Angeles Fernandez-Gonzalez, Monica Reis, S Alex Mitsialis, Stella Kourembanas

Int J Mol Sci· August 2018

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