Publications by authors named "Alex Papageorge"

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The pro-oncogenic noncanonical activity of a RAS•GTP:RanGAP1 complex facilitates nuclear protein export.
Brajendra K Tripathi, Nicole H Hirsh, Xiaolan Qian, Marian E Durkin, Dunrui Wang, Alex G Papageorge

Nat Cancer· December 2024

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Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein.
Brajendra K Tripathi, Meghan F Anderman, Disha Bhargava, Luciarita Boccuzzi, Xiaolan Qian, Alex G Papageorge

Nat Commun· December 2021

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Gain-of-Function Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer.
Haisheng Zhang, Antje Schaefer, Yichen Wang, Richard G Hodge, Devon R Blake, Alex G Papageorge

Cancer Discov· February 2020

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SRC and ERK cooperatively phosphorylate DLC1 and attenuate its Rho-GAP and tumor suppressor functions.
Brajendra K Tripathi, Meghan F Anderman, Xiaolan Qian, Ming Zhou, Dunrui Wang, Alex G Papageorge

J Cell Biol· September 2019

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RIT1 oncoproteins escape LZTR1-mediated proteolysis.
Pau Castel, Alice Cheng, Antonio Cuevas-Navarro, David B Everman, Alex G Papageorge

Science· March 2019

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Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1.
Brajendra K Tripathi, Tiera Grant, Xiaolan Qian, Ming Zhou, Philipp Mertins, Alex G Papageorge

J Cell Biol· December 2017

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CDK5 is a major regulator of the tumor suppressor DLC1.
Brajendra K Tripathi, Xiaolan Qian, Philipp Mertins, Dunrui Wang, Alex G Papageorge

J Cell Biol· December 2014

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Functional interaction of tumor suppressor DLC1 and caveolin-1 in cancer cells.
Xiaoli Du, Xiaolan Qian, Alex Papageorge, Aaron J Schetter, William C Vass

Cancer Res· September 2012

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Full activity of the deleted in liver cancer 1 (DLC1) tumor suppressor depends on an LD-like motif that binds talin and focal adhesion kinase (FAK).
Guorong Li, Xiaoli Du, William C Vass, Alex G Papageorge, Douglas R Lowy

Proc Natl Acad Sci U S A· October 2011

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The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis.
Xiaolan Qian, Guorong Li, William C Vass, Alex Papageorge, Renard C Walker

Cancer Cell· September 2009

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Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis.
Nigel P S Crawford, Xiaolan Qian, Argyrios Ziogas, Alex G Papageorge, Brenda J Boersma

PLoS Genet· November 2007

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Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities.
Xiaolan Qian, Guorong Li, Holly K Asmussen, Laura Asnaghi, William C Vass, Alex G Papageorge

Proc Natl Acad Sci U S A· May 2007

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