Publications by authors named "Alex Pickering"

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Transcriptional Profiling of Tofacitinib Treatment in Juvenile Idiopathic Arthritis: Implications for Treatment Response Prediction.
Esraa Eloseily, Alex Pickering, Sanjeev Dhakal, Nicolino Ruperto, Hermine I Brunner

Arthritis Care Res (Hoboken)· April 2025

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Disease Course, Treatments, and Outcomes of Children With Systemic Juvenile Idiopathic Arthritis-Associated Lung Disease.
Yannan Huang, Laura Sompii-Montgomery, Jessica Patti, Alex Pickering, Shima Yasin

Arthritis Care Res (Hoboken)· March 2024

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Recombinant Interleukin-1 Receptor Antagonist Is an Effective First-Line Treatment Strategy in New-Onset Systemic Juvenile Idiopathic Arthritis, Irrespective of HLA-DRB1 Background and IL1RN Variants.
Remco G A Erkens, Jorg J A Calis, Anouk Verwoerd, Sytze De Roock, Nienke M Ter Haar, Alex Pickering

Arthritis Rheumatol· January 2024

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Distinct Gene Expression Signatures Characterize Strong Clinical Responders Versus Nonresponders to Canakinumab in Children With Systemic Juvenile Idiopathic Arthritis.
Emely L Verweyen, Alex Pickering, Alexei A Grom, Grant S Schulert

Arthritis Rheumatol· July 2021

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Monocyte and bone marrow macrophage transcriptional phenotypes in systemic juvenile idiopathic arthritis reveal TRIM8 as a mediator of IFN-γ hyper-responsiveness and risk for macrophage activation syndrome.
Grant S Schulert, Alex V Pickering, Thuy Do, Sanjeev Dhakal, Ndate Fall

Ann Rheum Dis· May 2021

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Cross-modal representation alignment of molecular structure and perturbation-induced transcriptional profiles.
Samuel G Finlayson, Matthew B A McDermott, Alex V Pickering, Scott L Lipnick, Isaac S Kohane

Pac Symp Biocomput· April 2021

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Proceedings from the 2 Next Gen Therapies for Systemic Juvenile Idiopathic Arthritis and Macrophage Activation Syndrome symposium held on October 3-4, 2019.
Scott W Canna, Grant S Schulert, Adriana de Jesus, Alex Pickering, Hermine Brunner

Pediatr Rheumatol Online J· July 2020

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Mutagenesis of a conserved glutamate reveals the contribution of electrostatic energy to adenosylcobalamin co-C bond homolysis in ornithine 4,5-aminomutase and methylmalonyl-CoA mutase.
Caitlyn Makins, Alex V Pickering, Chloe Mariani, Kirsten R Wolthers

Biochemistry· February 2013

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