Publications by authors named "Alex Sykes"

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Parkinson's disease-linked Kir4.2 mutation R28C leads to loss of ion channel function.
Xiaoyi Chen, Rocio K Finol-Urdaneta, Mo Chen, Alex M Sykes, Bingmiao Gao

J Physiol· June 2025

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Circular RNAs in neurological conditions - computational identification, functional validation, and potential clinical applications.
Oak Hatzimanolis, Alex M Sykes, Alexandre S Cristino

Mol Psychiatry· April 2025

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Investigating pre-registration podiatry students approaches to identifying dermatology conditions in different skin tones: A mixed methods protocol.
Simon Otter, Deborah Whitham, Gianluca Melotto, Lauren Mann, Yaa Agyare, Alex Sykes

J Foot Ankle Res· December 2024

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The Impact of Obesity on Cardiorespiratory Fitness and Weight Changes in a Cardiac Rehabilitation Program.
Nikita Mittal, Christine Sonners, Janna Raphelson, Alex Sykes, Erin Roberts

J Cardiopulm Rehabil Prev· July 2024

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ER-phagy in neurodegeneration.
Melissa A Hill, Alex M Sykes, George D Mellick

J Neurosci Res· October 2023

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Novel Use of Cell Profiling Technology to Visualize Mitochondrial Responses of Humpback Whale Fibroblasts to Chemical Exposure.
Md Hafiz All Hosen, Alex M Sykes, Stephen A Wood, Frederic D L Leusch, Deanne J Whitworth

Environ Sci Technol· June 2023

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Modeling inducible neuropathologies of the retina with differential phenotypes in organoids.
Manuela Völkner, Felix Wagner, Thomas Kurth, Alex M Sykes, Claudia Del Toro Runzer

Front Cell Neurosci· May 2023

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The role of the endolysosomal pathway in α-synuclein pathogenesis in Parkinson's disease.
Jessica K Smith, George D Mellick, Alex M Sykes

Front Cell Neurosci· January 2023

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Proteomic profiling of idiopathic Parkinson's disease primary patient cells by SWATH-MS.
Stephen A Wood, Peter G Hains, Arnaud Muller, Melissa Hill, Susitha Premarathne, Alex M Sykes

Proteomics Clin Appl· September 2022

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Does a rare mutation in PTPRA contribute to the development of Parkinson's disease in an Australian multi-incident family?
Melissa A Hill, Steven R Bentley, Tara L Walker, George D Mellick, Stephen A Wood, Alex M Sykes

PLoS One· August 2022

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Apple Peel and Flesh Contain Pro-neurogenic Compounds.
Muhammad Ichwan, Tara L Walker, Zeina Nicola, Jutta Ludwig-Müller, Christoph Böttcher, Alex M Sykes

Stem Cell Reports· March 2021

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Hunting for Familial Parkinson's Disease Mutations in the Post Genome Era.
Steven R Bentley, Ilaria Guella, Holly E Sherman, Hannah M Neuendorf, Alex M Sykes

Genes (Basel)· March 2021

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ROS Dynamics Delineate Functional States of Hippocampal Neural Stem Cells and Link to Their Activity-Dependent Exit from Quiescence.
Vijay S Adusumilli, Tara L Walker, Rupert W Overall, Gesa M Klatt, Salma A Zeidan, Alex M Sykes

Cell Stem Cell· February 2021

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Evidence of a Recessively Inherited CCN3 Mutation as a Rare Cause of Early-Onset Parkinsonism.
Steven R Bentley, Suliman Khan, Marco Öchsner, Susitha Premarathne, Zain Aslam, Alex M Sykes

Front Neurol· May 2020

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Retinal cell death dependent reactive proliferative gliosis in the mouse retina.
Sheik Pran Babu Sardar Pasha, Robert Münch, Patrick Schäfer, Peter Oertel, Alex M Sykes

Sci Rep· August 2017

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Prominin-1 (CD133) and the Cell Biology of Neural Progenitors and Their Progeny.
Alex M Sykes, Wieland B Huttner

Adv Exp Med Biol· April 2016

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Lysophosphatidic Acid Receptor Is a Functional Marker of Adult Hippocampal Precursor Cells.
Tara L Walker, Rupert W Overall, Steffen Vogler, Alex M Sykes, Susann Ruhwald

Stem Cell Reports· April 2016

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Human cerebral organoids recapitulate gene expression programs of fetal neocortex development.
J Gray Camp, Farhath Badsha, Marta Florio, Sabina Kanton, Tobias Gerber, Alex Sykes

Proc Natl Acad Sci U S A· December 2015

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Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion.
Marta Florio, Mareike Albert, Elena Taverna, Takashi Namba, Holger Brandl, Alex Sykes

Science· March 2015

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An intracellular domain fragment of the p75 neurotrophin receptor (p75(NTR)) enhances tropomyosin receptor kinase A (TrkA) receptor function.
Dusan Matusica, Sune Skeldal, Alex M Sykes, Nickless Palstra, Aanchal Sharma

J Biol Chem· April 2013

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HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.
Kristin Franke, Joanna Kalucka, Soulafa Mamlouk, Rashim Pal Singh, Antje Muschter, Alex M Sykes

Blood· February 2013

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Prominin-1 allows prospective isolation of neural stem cells from the adult murine hippocampus.
Tara L Walker, Ann Wierick, Alex M Sykes, Ben Waldau, Denis Corbeil

J Neurosci· February 2013

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Prolactin stimulates precursor cells in the adult mouse hippocampus.
Tara L Walker, Jana Vukovic, Margaretha M Koudijs, Daniel G Blackmore, Eirinn W Mackay, Alex M Sykes

PLoS One· January 2013

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The effects of transmembrane sequence and dimerization on cleavage of the p75 neurotrophin receptor by γ-secretase.
Alex M Sykes, Nickless Palstra, Daniel Abankwa, Justine M Hill, Sune Skeldal

J Biol Chem· December 2012

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Mapping of the interaction site between sortilin and the p75 neurotrophin receptor reveals a regulatory role for the sortilin intracellular domain in p75 neurotrophin receptor shedding and apoptosis.
Sune Skeldal, Alex M Sykes, Simon Glerup, Dusan Matusica, Nickless Palstra

J Biol Chem· December 2012

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