Publications by authors named "Alex Vassilev"

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Selective elimination of pluripotent stem cells by PIKfyve specific inhibitors.
Arup R Chakraborty, Alex Vassilev, Sushil K Jaiswal, Constandina E O'Connell, John F Ahrens

Stem Cell Reports· February 2022

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Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells.
Constandina E O'Connell, Alex Vassilev

Cancer Res· June 2021

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A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis.
Gaurav Sharma, Carlos M Guardia, Ajit Roy, Alex Vassilev, Amra Saric

Autophagy· October 2019

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Links between DNA Replication, Stem Cells and Cancer.
Alex Vassilev, Melvin L DePamphilis

Genes (Basel)· January 2017

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Identification of genes that are essential to restrict genome duplication to once per cell division.
Alex Vassilev, Chrissie Y Lee, Boris Vassilev, Wenge Zhu, Pinar Ormanoglu

Oncotarget· June 2016

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Defective i6A37 modification of mitochondrial and cytosolic tRNAs results from pathogenic mutations in TRIT1 and its substrate tRNA.
John W Yarham, Tek N Lamichhane, Angela Pyle, Sandy Mattijssen, Enrico Baruffini, Alex Vassilev

PLoS Genet· June 2014

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A Ca2+-dependent mechanism of neuronal survival mediated by the microtubule-associated protein p600.
Camille Belzil, Gernot Neumayer, Alex P Vassilev, Kyoko L Yap, Hiroaki Konishi

J Biol Chem· August 2013

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Assembly of the human origin recognition complex occurs through independent nuclear localization of its components.
Soma Ghosh, Alex P Vassilev, Junmei Zhang, Yingming Zhao, Melvin L DePamphilis

J Biol Chem· July 2011

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Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors.
Pallavi Bhattaram, Alfredo Penzo-Méndez, Elisabeth Sock, Clemencia Colmenares, Kotaro J Kaneko, Alex Vassilev

Nat Commun· April 2010

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Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex.
Hyongi Chon, Alex Vassilev, Melvin L DePamphilis, Yingming Zhao, Junmei Zhang

Nucleic Acids Res· January 2009

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The BAH domain facilitates the ability of human Orc1 protein to activate replication origins in vivo.
Kohji Noguchi, Alex Vassilev, Soma Ghosh, John L Yates, Melvin L DePamphilis

EMBO J· November 2006

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Genetic analysis of human Orc2 reveals specific domains that are required in vivo for assembly and nuclear localization of the origin recognition complex.
Ilian Radichev, Sung Won Kwon, Yingming Zhao, Melvin L DePamphilis, Alex Vassilev

J Biol Chem· August 2006

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Regulating the licensing of DNA replication origins in metazoa.
Melvin L DePamphilis, J Julian Blow, Soma Ghosh, Tapas Saha, Kohji Noguchi, Alex Vassilev

Curr Opin Cell Biol· June 2006

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Ubiquitylation, phosphorylation and Orc2 modulate the subcellular location of Orc1 and prevent it from inducing apoptosis.
Tapas Saha, Soma Ghosh, Alex Vassilev, Melvin L DePamphilis

J Cell Sci· April 2006

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p600, a unique protein required for membrane morphogenesis and cell survival.
Yoshihiro Nakatani, Hiroaki Konishi, Alex Vassilev, Hisanori Kurooka, Keiichiro Ishiguro

Proc Natl Acad Sci U S A· October 2005

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Nonphosphorylated human La antigen interacts with nucleolin at nucleolar sites involved in rRNA biogenesis.
Robert V Intine, Miroslav Dundr, Alex Vassilev, Elena Schwartz, Yingmin Zhao

Mol Cell Biol· December 2004

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Role for Cdk1 (Cdc2)/cyclin A in preventing the mammalian origin recognition complex's largest subunit (Orc1) from binding to chromatin during mitosis.
Cong-jun Li, Alex Vassilev, Melvin L DePamphilis

Mol Cell Biol· July 2004

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Human histone deacetylase SIRT2 interacts with the homeobox transcription factor HOXA10.
Nancy S Bae, Mark J Swanson, Alex Vassilev, Bruce H Howard

J Biochem· June 2004

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