Publications by authors named "Alexander Borowsky"

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WISDOM Randomized Trial Comparing Risk-Based Versus Annual Breast Cancer Screening: Study Cohort Characteristics and Design.
Allison Fiscalini, Kelly Blum, Kirkpatrick Fergus, Robert A Hiatt, Arash Naeim, Alexander D Borowsky

Res Sq· December 2025

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Risk-Based vs Annual Breast Cancer Screening: The WISDOM Randomized Clinical Trial.
Laura J Esserman, Allison S Fiscalini, Arash Naeim, Laura J Van't Veer, Andrea Kaster, Alexander D Borowsky

JAMA· December 2025

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Germline Pathogenic Variants Among Women Without a History of Breast Cancer: A Secondary Analysis of the WISDOM Randomized Clinical Trial.
Kirkpatrick B Fergus, Katherine S Ross, Maren T Scheuner, Amie M Blanco, Jeffrey A Tice, Alexander D Borowsky

JAMA Intern Med· December 2025

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A Multicenter Study to Evaluate Diagnostic Accuracy by Pathologists Using the Aperio GT 450 DX in Local and Remote Viewing Stations.
Alexander D Borowsky, Dylan V Miller, Thomas W Bauer, Richard M Feddersen, Dorina Gui

Arch Pathol Lab Med· September 2025

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Roche Digital Pathology Dx whole slide imaging system is comparable to traditional microscopy for primary diagnosis in surgical pathology.
Keith A Wharton, Jim Ranger-Moore, Hon Seng, Alexander D Borowsky, Cynthia A Behling

Am J Clin Pathol· September 2025

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Integration of Gene Expression and Digital Histology to Predict Treatment-Specific Responses in Breast Cancer.
Frederick M Howard, James Dolezal, Hanna Hieromnimon, Sara Venters, Sara Kochanny, Alexander Borowsky

medRxiv· August 2025

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Immune Subtyping Identifies Patients With Hormone Receptor-Positive Early-Stage Breast Cancer Who Respond to Neoadjuvant Immunotherapy (IO): Results From Five IO Arms of the I-SPY2 Trial.
Denise M Wolf, Christina Yau, Michael Campbell, Annuska Glas, Andrei Barcaru, Alexander Borowsky

JCO Precis Oncol· June 2025

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POLE Mutation Associated With Microsatellite Instability and High Tumor Mutational Burden Confers Exquisite Sensitivity to Immune Checkpoint Inhibitor Therapy in Non-Small Cell Lung Cancer: A Case Report and Genomic Database Analysis.
Matthew S Lara, Jonathan W Riess, Guneet Kaleka, Alexander Borowsky, John D McPherson

Clin Lung Cancer· May 2025

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Intratumoral Injection of mRNA-2752 and Pembrolizumab for High-Risk Ductal Carcinoma In Situ: A Phase 1 Nonrandomized Clinical Trial.
Kirithiga Ramalingam, Rachel Woody, Alexa Glencer, Christopher J Schwartz, Hidetoshi Mori, Alexander D Borowsky

JAMA Oncol· March 2025

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Nonlinear progression during the occult transition establishes cancer lethality.
Joshua D Ginzel, Henry Chapman, Joelle E Sills, Edwin J Allen, Lawrence S Barak, Alexander D Borowsky

Dis Model Mech· March 2025

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Adaptive selection of p53 mutation metaplastic phenotypes in estrogen-independent progression of ER+ tumors: A mechanism for acquired resistance to hormonal therapy.
Hyeongsun Moon, Hidetoshi Mori, Jane Chen, Alejandra Patino, Zsofia Penzvalto, Alexander D Borowsky

bioRxiv· February 2025

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Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for early-stage breast cancer.
Michael J Campbell, Denise M Wolf, Christina Yau, Lamorna Brown-Swigart, Julie Wulfkuhle, Alexander Borowsky

Cell Rep Med· November 2024

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Functional inversion of circadian regulator REV-ERBα leads to tumorigenic gene reprogramming.
Yatian Yang, Xiong Zhang, Demin Cai, Xingling Zheng, Xuan Zhao, Alexander D Borowsky

Proc Natl Acad Sci U S A· October 2024

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Peripheral-derived regulatory T cells contribute to tumor-mediated immune suppression in a nonredundant manner.
Md Moazzem Hossain, Paul King, Justin Hackett, Herve C Gerard, Rajmund Niwinski, Alexander D Borowsky

Proc Natl Acad Sci U S A· September 2024

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Nonlinear progression during the occult transition establishes cancer lethality.
Joshua D Ginzel, Henry Chapman, Joelle E Sills, Edwin J Allen, Lawrence S Barak, Alexander D Borowsky

bioRxiv· August 2024

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Superficial Neurocristic EWSR1::FLI1 Fusion Tumor: A Distinctive, Clinically Indolent, S100 Protein/SOX10-Positive Neoplasm.
Andrew L Folpe, Michael T Tetzlaff, Steven D Billings, Jorge Torres-Mora, Alexander David Borowsky

Mod Pathol· August 2024

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Rewiring gene circuitry for plant improvement.
Alexander T Borowsky, Julia Bailey-Serres

Nat Genet· August 2024

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Magnetic resonance imaging insights from active surveillance of women with ductal carcinoma in situ.
Heather I Greenwood, Cristian K Maldonado Rodas, Rita I Freimanis, Alexa C Glencer, Phoebe N Miller, Alexander Borowsky

NPJ Breast Cancer· August 2024

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Melanoma progression and prognostic models drawn from single-cell, spatial maps of benign and malignant tumors.
Nick R Love, Claire Williams, Emily E Killingbeck, Alexander Merleev, Mohammad Saffari Doost, Alexander D Borowsky

Sci Adv· July 2024

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Tumor microenvironmental determinants of high-risk DCIS progression.
Alexander Borowsky, Alexa Glencer, Kirithiga Ramalingam, Nicole Schindler, Hidetoshi Mori

Res Sq· May 2024

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GigaFIBI; Rapid, Large-format Histology-resolution Imaging for Intraoperative Assessment of Breast Lumpectomy Margins.
Dena Sayrafi, Nate Anderson, Candice Sauder, Diana Miglioretti, Richard Levenson, Alexander Borowsky

Biomed Opt· April 2024

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spatialHeatmap: visualizing spatial bulk and single-cell assays in anatomical images.
Jianhai Zhang, Le Zhang, Brendan Gongol, Jordan Hayes, Alexander T Borowsky

NAR Genom Bioinform· March 2024

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Engrailed-1 Promotes Pancreatic Cancer Metastasis.
Jihao Xu, Jae-Seok Roe, EunJung Lee, Claudia Tonelli, Keely Y Ji, Alexander D Borowsky

Adv Sci (Weinh)· February 2024

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A suberized exodermis is required for tomato drought tolerance.
Alex Cantó-Pastor, Kaisa Kajala, Lidor Shaar-Moshe, Concepción Manzano, Prakash Timilsena, Alexander T Borowsky

Nat Plants· January 2024

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Neuropathological Applications of Microscopy with Ultraviolet Surface Excitation (MUSE): A Concordance Study of Human Primary and Metastatic Brain Tumors.
Mirna Lechpammer, Austin Todd, Vivian Tang, Taryn Morningstar, Alexander Borowsky

Brain Sci· January 2024

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