Publications by authors named "Alexander D Crawford"

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Dietary yeast improves zebrafish immunity and survival against Aeromonas infection.
Kathiresan Purushothaman, Sérgio D C Rocha, Daanish Kaul, Aleksandar B Goksu, Byron Morales-Lange, Alexander D Crawford

Fish Shellfish Immunol· December 2025

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Turmerone-loaded nanocarriers effectively induced apoptosis and attenuated cancerous phenotype inin vitroandin vivoHCC models.
Roghayeh Naserkhaki, Ali Zarrabi, Mahdieh Hashemi, Alexander D Crawford, Haleh Bakhshandeh

Colloids Surf B Biointerfaces· October 2025

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Effectiveness of add-on acetazolamide in children with drug-resistant CHD2-related epilepsy and in a zebrafish CHD2 model.
Gia Melikishvili, Pasquale Striano, Elham Shojeinia, Tamar Gachechiladze, Ekaterine Kurua, Alexander D Crawford

Epilepsia Open· October 2024

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Deoxyhypusine synthase deficiency syndrome zebrafish model: aberrant morphology, epileptiform activity, and reduced arborization of inhibitory interneurons.
Elham Shojaeinia, Teresa L Mastracci, Remon Soliman, Orrin Devinsky, Camila V Esguerra, Alexander D Crawford

Mol Brain· September 2024

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CLN3 deficiency leads to neurological and metabolic perturbations during early development.
Ursula Heins-Marroquin, Randolph R Singh, Simon Perathoner, Floriane Gavotto, Carla Merino Ruiz, Alexander D Crawford

Life Sci Alliance· March 2024

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yeast as a functional protein source: Modulation of immunoregulatory pathways in the intestinal proteome of zebrafish ().
Kathiresan Purushothaman, Alexander D Crawford, Sérgio D C Rocha, Aleksandar B Göksu, Byron Morales Lange

Heliyon· March 2024

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Natural product-derived therapies for treating drug-resistant epilepsies: From ethnopharmacology to evidence-based medicine.
Soura Challal, Adrianna Skiba, Mélanie Langlois, Camila V Esguerra, Jean-Luc Wolfender, Alexander D Crawford

J Ethnopharmacol· December 2023

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Seizure-induced increase in microglial cell population in the developing zebrafish brain.
Teresa G Martins, Remon Soliman, Maria Lorena Cordero-Maldonado, Cristina Donato, Corrado Ameli, Alexander D Crawford

Epilepsy Res· September 2023

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Evaluation of the wound healing properties of South African medicinal plants using zebrafish and in vitro bioassays.
Fikile Mhlongo, Maria Lorena Cordero-Maldonado, Alexander D Crawford, David Katerere, Maxleene Sandasi

J Ethnopharmacol· March 2022

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Australindolones, New Aminopyrimidine Substituted Indolone Alkaloids from an Antarctic Tunicate sp.
Sofia Kokkaliari, Kim Pham, Nargess Shahbazi, Laurent Calcul, Lukasz Wojtas, Alexander D Crawford

Mar Drugs· March 2022

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From the North Sea to Drug Repurposing, the Antiseizure Activity of Halimide and Plinabulin.
Daniëlle Copmans, Sara Kildgaard, Emma Roux, Michèle Partoens, Gert Steurs, Alexander D Crawford

Pharmaceuticals (Basel)· February 2022

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Anti-seizure activity of African medicinal plants: The identification of bioactive alkaloids from the stem bark of Rauvolfia caffra using an in vivo zebrafish model.
Talent Chipiti, Alvaro M Viljoen, Maria L Cordero-Maldonado, Clinton G L Veale, Fanie R Van Heerden, Alexander D Crawford

J Ethnopharmacol· October 2021

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Identification of Potential Antiseizure Agents in using Zebrafish and Mouse Epilepsy Models.
Théo Brillatz, Maxime Jacmin, Emerson F Queiroz, Laurence Marcourt, Hugo Morin, Alexander D Crawford

ACS Chem Neurosci· May 2021

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l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain.
Remon Soliman, Maria Lorena Cordero-Maldonado, Teresa G Martins, Mahsa Moein, Jean-François Conrotte, Alexander D Crawford

Front Genet· January 2021

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Antiseizure potential of the ancient Greek medicinal plant Helleborus odorus subsp. cyclophyllus and identification of its main active principles.
Théo Brillatz, Maxime Jacmin, Konstantina Vougogiannopoulou, Eleftherios A Petrakis, Eleftherios Kalpoutzakis, Alexander D Crawford

J Ethnopharmacol· September 2020

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Seizing the moment: Zebrafish epilepsy models.
Kinga Gawel, Melanie Langlois, Teresa Martins, Wietske van der Ent, Ettore Tiraboschi, Alexander D Crawford

Neurosci Biobehav Rev· September 2020

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Metabolite Profiling of Javanese Ginger and Identification of Antiseizure Metabolites via a Low-Cost Open-Source Zebrafish Bioassay-Guided Isolation.
Théo Brillatz, Miwa Kubo, Shimon Takahashi, Natsumi Jozukuri, Kenshi Takechi, Alexander D Crawford

J Agric Food Chem· July 2020

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Zebrafish bioassay-guided isolation of antiseizure compounds from the Cameroonian medicinal plant Cyperus articulatus L.
Théo Brillatz, Maxime Jacmin, Emerson Ferreira Queiroz, Laurence Marcourt, Ivan Slacanin, Alexander D Crawford

Phytomedicine· April 2020

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Fishing for a deeper understanding of nicotine effects using zebrafish behavioural models.
Olga Wronikowska, Agnieszka Michalak, Krystyna Skalicka-Woźniak, Alexander D Crawford, Barbara Budzyńska

Prog Neuropsychopharmacol Biol Psychiatry· March 2020

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Zebrafish-Based Discovery of Antiseizure Compounds from the North Sea: Isoquinoline Alkaloids TMC-120A and TMC-120B.
Daniëlle Copmans, Sara Kildgaard, Silas A Rasmussen, Monika Ślęzak, Nina Dirkx, Alexander D Crawford

Mar Drugs· October 2019

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Deep learning image recognition enables efficient genome editing in zebrafish by automated injections.
Maria Lorena Cordero-Maldonado, Simon Perathoner, Kees-Jan van der Kolk, Ralf Boland, Ursula Heins-Marroquin, Alexander D Crawford

PLoS One· September 2019

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Phenotypic assays in yeast and zebrafish reveal drugs that rescue deficiency.
Ursula Heins-Marroquin, Paul P Jung, Maria Lorena Cordero-Maldonado, Alexander D Crawford, Carole L Linster

Brain Commun· September 2019

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Identification of GSK-3 as a Potential Therapeutic Entry Point for Epilepsy.
Najat Aourz, Ann-Sophie K Serruys, Joëlle N Chabwine, Pascal Byenda Balegamire, Tatiana Afrikanova, Alexander D Crawford

ACS Chem Neurosci· April 2019

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High-performance counter-current chromatography isolation and initial neuroactivity characterization of furanocoumarin derivatives from Peucedanum alsaticum L (Apiaceae).
Ewelina Kozioł, Fatma Sezer Senol Deniz, Ilkay Erdogan Orhan, Laurence Marcourt, Barbara Budzyńska, Alexander D Crawford

Phytomedicine· February 2019

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Zebrafish-based identification of the antiseizure nucleoside inosine from the marine diatom Skeletonema marinoi.
Théo Brillatz, Chiara Lauritano, Maxime Jacmin, Supitcha Khamma, Laurence Marcourt, Alexander D Crawford

PLoS One· July 2018

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