Publications by authors named "Alexander D Giddey"

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Optimizing MS Parameters for Data-Independent Acquisition (DIA) to Enhance Untargeted Metabolomics.
Frederico G Pinto, Alexander D Giddey, Rouda S B Almarri, Omer S Alkhnbashi, Timothy J Garrett

J Proteome Res· December 2025

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Impact of PPP1R1A Knockdown on the Proteomic Landscape of INS-1 Cells: A Focus on Significant Modulated Pathways.
Jalal Taneera, Alexander D Giddey, Nelson C Soares, Anila Khalique, Abdul Khader Mohammed

J Proteome Res· December 2025

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Identifying the Impact of RelA Overexpression in Triple-Negative Breast Cancer Cells Using Mass Spectroscopy-based Proteomics and Metabolomics Analysis.
Dana M Zaher, Shifaa M Abdin, Mohammad H Semreen, Hamza M Al-Hroub, Alexander D Giddey

Chem Biodivers· November 2025

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Investigating the Role of Coenzyme A Restriction in the Pathophysiology of Preeclampsia: Protocol for a Combined Patient Screening and Laboratory Study.
Reem Al-Jayyousi, Reem K Jan, Alexander D Giddey, Adrian G Stanley, Anagha Parambath

JMIR Res Protoc· October 2025

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Repurposing proteomic nanoLC-MS platforms for untargeted metabolomics: evaluating DIA and polarity switching performance in human plasma.
Frederico G Pinto, Alexander D Giddey, Nesrin Mohamed, Rauda S B Almarri, Munazza Murtaza

Expert Rev Proteomics· August 2025

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Medwakh smoking induces alterations in salivary proteins and cytokine expression: a clinical exploratory proteomics investigation.
K G Aghila Rani, Nelson C Soares, Betul Rahman, Alexander D Giddey, Hamza M Al-Hroub

Clin Proteomics· January 2025

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Comparative proteomic analysis of saliva from chewing tobacco users and oral cancer patients reveals shared biomarkers: A case control observational study.
Alexander D Giddey, Yousra A Hagyousif, Nelson C Soares, Hamza M Al-Hroub, K G Aghila Rani

J Dent· October 2024

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Serum multi-omics analysis in hindlimb unloading mice model: Insights into systemic molecular changes and potential diagnostic and therapeutic biomarkers.
Zeinab Ibrahim, Naveed A Khan, Rizwan Qaisar, Mohamed A Saleh, Ruqaiyyah Siddiqui, Alexander D Giddey

Heliyon· January 2024

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Proteomic and metabolomic signatures of U87 glioblastoma cells treated with cisplatin and/or paclitaxel.
Munazza Ahmed, Ahlam M Semreen, Alexander D Giddey, Wafaa S Ramadan, Raafat El-Awady

Ann Med· January 2024

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Multi-Omics Profiling of Grown on Solid Versus Liquid Media.
Rouba Abdulsalam Alhameed, Mohammad H Semreen, Mohamad Hamad, Alexander D Giddey, Ashna Sulaiman

Microorganisms· November 2023

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Selected Gut Bacteria from Water Monitor Lizard Exhibit Effects against Pathogenic Belonging to the T4 Genotype.
Noor Akbar, Naveed Ahmed Khan, Alexander D Giddey, Nelson C Soares, Ahmad M Alharbi

Microorganisms· April 2023

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Evaluation of Two Simultaneous Metabolomic and Proteomic Extraction Protocols Assessed by Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry.
Ruba A Zenati, Alexander D Giddey, Hamza M Al-Hroub, Yousra A Hagyousif, Waseem El-Huneidi

Int J Mol Sci· January 2023

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Skin Cancer Metabolic Profile Assessed by Different Analytical Platforms.
Yousra A Hagyousif, Basma M Sharaf, Ruba A Zenati, Waseem El-Huneidi, Yasser Bustanji, Alexander D Giddey

Int J Mol Sci· January 2023

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Ramadan diurnal intermittent fasting is associated with significant plasma metabolomics changes in subjects with overweight and obesity: A prospective cohort study.
Mohamed Madkour, Alexander D Giddey, Nelson C Soares, Mohammad H Semreen, Yasser Bustanji

Front Nutr· January 2023

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Mass spectroscopy-based proteomics and metabolomics analysis of triple-positive breast cancer cells treated with tamoxifen and/or trastuzumab.
Basma M Sharaf, Alexander D Giddey, Hamza M Al-Hroub, Varsha Menon, Javan Okendo

Cancer Chemother Pharmacol· December 2022

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Multi-Omics Analysis Revealed a Significant Alteration of Critical Metabolic Pathways Due to Sorafenib-Resistance in Hep3B Cell Lines.
Kholoud Y I Abushawish, Sameh S M Soliman, Alexander D Giddey, Hamza M Al-Hroub, Muath Mousa

Int J Mol Sci· October 2022

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Unveiling the mechanism of action of nature-inspired anti-cancer compounds using a multi-omics approach.
Nelson C Soares, Amjad Ali, Vunnam Srinivasulu, Basma M Sharaf, Alexander D Giddey

J Proteomics· August 2022

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Proteomic Approaches to Unravel Mechanisms of Antibiotic Resistance and Immune Evasion of Bacterial Pathogens.
Eva Torres-Sangiao, Alexander Dyason Giddey, Cristina Leal Rodriguez, Zhiheng Tang, Xiaoyun Liu

Front Med (Lausanne)· May 2022

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Untargeted Metabolomics of Breast Cancer Cells MCF-7 and SkBr3 Treated With Tamoxifen/Trastuzumab.
Basma M Sharaf, Alexander D Giddey, Hasan Alniss, Hamza M Al-Hroub, Raafat El-Awady

Cancer Genomics Proteomics· March 2022

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Cell Wall Proteomics Reveal Phenotypic Adaption of Drug-Resistant to Subinhibitory Rifampicin Exposure.
Alexander D Giddey, Tariq A Ganief, Naadir Ganief, Anastasia Koch, Digby F Warner

Front Med (Lausanne)· October 2021

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Cell wall enrichment unveils proteomic changes in the cell wall during treatment of Mycobacterium smegmatis with sub-lethal concentrations of rifampicin.
Clemens Hermann, Alexander D Giddey, Andrew J M Nel, Nelson C Soares, Jonathan M Blackburn

J Proteomics· January 2019

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Gel-free sample preparation techniques and bioinformatic enrichment analysis to in depth characterise the cell wall proteome of mycobacteria.
Clemens Hermann, Alexander D Giddey, Andrew J M Nel, Nelson C Soares, Jonathan M Blackburn

MethodsX· May 2018

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A temporal proteome dynamics study reveals the molecular basis of induced phenotypic resistance in Mycobacterium smegmatis at sub-lethal rifampicin concentrations.
Alexander D Giddey, Elise de Kock, Kehilwe C Nakedi, Shaun Garnett, Andrew J M Nel

Sci Rep· March 2017

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