Publications by authors named "Alexander D Guminski"

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Development of a First-in-Class Click Chemistry-Based Cancer Therapeutic, from Preclinical Evaluation to a First-in-Human Dose Escalation Clinical Trial.
Sangeetha Srinivasan, Nathan A Yee, Maša Alečković, Michael Zakharian, Amir Mahmoodi, Alexander D Guminski

Clin Cancer Res· September 2025

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Ipilimumab plus nivolumab versus nivolumab alone in patients with melanoma brain metastases (ABC): 7-year follow-up of a multicentre, open-label, randomised, phase 2 study.
Georgina V Long, Victoria Atkinson, Serigne N Lo, Alexander D Guminski, Shahneen K Sandhu

Lancet Oncol· March 2025

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Immune checkpoint inhibitor therapy for advanced cutaneous squamous cell carcinoma in Australia: a retrospective real world cohort study.
Luke S McLean, Annette M Lim, Mathias Bressel, Jenny Lee, Rahul Ladwa, Alexander D Guminski

Med J Aust· February 2024

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Health-related quality of life in patients with melanoma brain metastases treated with immunotherapy.
Jake R Thompson, Julia Lai-Kwon, Rachael L Morton, Alexander D Guminski, Maria Gonzalez

Immunotherapy· June 2023

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Genomic Profiling of Metastatic Basal cell Carcinoma Reveals Candidate Drivers of Disease and Therapeutic Targets.
Ismael A Vergara, Karina Aivazian, Matteo S Carlino, Alexander D Guminski, Nigel G Maher

Mod Pathol· April 2023

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Long-term Follow-up of Standard-Dose Pembrolizumab Plus Reduced-Dose Ipilimumab in Patients with Advanced Melanoma: KEYNOTE-029 Part 1B.
Matteo S Carlino, Alexander M Menzies, Victoria Atkinson, Jonathan S Cebon, Michael B Jameson, Alexander D Guminski

Clin Cancer Res· October 2020

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Response to Letter to the Editor: "Checkpoint Inhibitor-Associated Autoimmune Diabetes is Distinct From Type 1 Diabetes".
Venessa H M Tsang, Rachel T McGrath, Roderick J Clifton-Bligh, Richard A Scolyer, Valerie Jakrot, Alexander D Guminski

J Clin Endocrinol Metab· June 2020

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Checkpoint Inhibitor-Associated Autoimmune Diabetes Is Distinct From Type 1 Diabetes.
Venessa H M Tsang, Rachel T McGrath, Roderick J Clifton-Bligh, Richard A Scolyer, Valerie Jakrot, Alexander D Guminski

J Clin Endocrinol Metab· November 2019

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Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial.
Elisa A Rozeman, Alexander M Menzies, Alexander C J van Akkooi, Chandra Adhikari, Carolien Bierman, Alexander D Guminski

Lancet Oncol· July 2019

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Characteristics and outcomes of oncology unit patients requiring admission to an Australian intensive care unit.
Aaron C Tan, Sarah K Jacques, Meredith Oatley, Alexander D Guminski

Intern Med J· June 2019

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Survival and prognostic factors for patients with melanoma brain metastases in the era of modern systemic therapy.
Martin Tio, Xuan Wang, Matteo S Carlino, Brindha Shivalingam, Gerald B Fogarty, Alexander D Guminski

Pigment Cell Melanoma Res· July 2018

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Combination nivolumab and ipilimumab or nivolumab alone in melanoma brain metastases: a multicentre randomised phase 2 study.
Georgina V Long, Victoria Atkinson, Serigne Lo, Shahneen Sandhu, Alexander D Guminski

Lancet Oncol· May 2018

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Standard-dose pembrolizumab in combination with reduced-dose ipilimumab for patients with advanced melanoma (KEYNOTE-029): an open-label, phase 1b trial.
Georgina V Long, Victoria Atkinson, Jonathan S Cebon, Michael B Jameson, Bernie M Fitzharris, Alexander D Guminski

Lancet Oncol· September 2017

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Pneumonitis in Patients Treated With Anti-Programmed Death-1/Programmed Death Ligand 1 Therapy.
Jarushka Naidoo, Xuan Wang, Kaitlin M Woo, Tunc Iyriboz, Darragh Halpenny, Alexander D Guminski

J Clin Oncol· March 2017

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Cisplatin treatment induces a transient increase in tumorigenic potential associated with high interleukin-6 expression in head and neck squamous cell carcinoma.
Kim J Poth, Alexander D Guminski, Gethin P Thomas, Paul J Leo, Ibtissam A Jabbar

Mol Cancer Ther· August 2010

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Predicting response to IL-2 therapy for metastatic melanoma.
Alexander D Guminski, John F Thompson

Expert Rev Anticancer Ther· November 2009

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Ankyrin repeat domain 1, ANKRD1, a novel determinant of cisplatin sensitivity expressed in ovarian cancer.
Lyndee L Scurr, Alexander D Guminski, Yoke-Eng Chiew, Rosemary L Balleine, Raghwa Sharma

Clin Cancer Res· November 2008

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MRP2 (ABCC2) and cisplatin sensitivity in hepatocytes and human ovarian carcinoma.
Alexander D Guminski, Rosemary L Balleine, Yoke-Eng Chiew, Lucy R Webster, Michael Tapner

Gynecol Oncol· February 2006

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Scientists and clinicians test their metal-back to the future with platinum compounds.
Alexander D Guminski, Paul R Harnett, Anna deFazio

Lancet Oncol· May 2002

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