Publications by authors named "Alexander Domling"

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Precipitation-first synthesis and deep profiling of a 1200-member acrylamide library for covalent drug discovery.
Pravin Patil, Emis Ingenito, Riccardo Fusco, Imma Capriello, Zhirui Guan

Green Chem· November 2025

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Balinatunfib: A Clinical Oral Small Molecule TNFα Inhibitor.
Alexander Dömling, Tad A Holak

ChemMedChem· July 2025

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Colchicine-BODIPY Probes: Evidence for the Involvement of Intracellular Membranes in the Targeting of Colchicine to Tubulin.
Michal Jurášek, Eduarda Dráberová, Jiří Řehulka, Soňa Gurská, Aleksandra Ivanova

ACS Pharmacol Transl Sci· July 2025

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Exploring Aspartate Transcarbamoylase: A Promising Broad-Spectrum Target for Drug Development.
Siyao Chen, Queenie Mondile, XiaoChen Du, Chao Wang, Mayur Mukim

Chembiochem· April 2025

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CBL-B - An upcoming immune-oncology target.
Riccardo Fusco, Zeinab Saedi, Imma Capriello, Andriy Lubskyy, Alexander Dömling

Expert Opin Ther Pat· January 2025

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Small-Molecule Allosteric Inhibitors of Human Aspartate Transcarbamoylase Suppress Proliferation of Bone Osteosarcoma Epithelial Cells.
Chao Wang, Bidong Zhang, Yingying Cong, Xiaochen Du, Siyao Chen

ChemMedChem· July 2024

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Correction: Reyes Romero et al. Computer- and NMR-Aided Design of Small-Molecule Inhibitors of the Hub1 Protein. 2022, , 8282.
Atilio Reyes Romero, Katarzyna Kubica, Radoslaw Kitel, Ismael Rodríguez, Katarzyna Magiera-Mularz

Molecules· June 2024

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Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies.
Sanjeev Raghuwanshi, Xu Zhang, Zarema Arbieva, Irum Khan, Hisham Mohammed, Alexander Domling

Cell Death Discov· May 2024

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Joint Effects of Exercise and Ramadan Fasting on Telomere Length: Implications for Cellular Aging.
Shamma Almuraikhy, Maha Sellami, Khaled Naja, Hadaia Saleh Al-Amri, Najeha Anwardeen

Biomedicines· May 2024

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Activation of p53 signaling and regression of breast and prostate carcinoma cells by spirooxindole-benzimidazole small molecules.
Assem Barakat, Saeed Alshahrani, Abdullah Mohammed Al-Majid, Abdullah Saleh Alamary, Matti Haukka

Front Pharmacol· April 2024

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1,5-Disubstituted tetrazoles as PD-1/PD-L1 antagonists.
Robin van der Straat, Rosalie Draijer, Ewa Surmiak, Roberto Butera, Lennart Land

RSC Med Chem· April 2024

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Innovative synthesis of drug-like molecules using tetrazole as core building blocks.
Jingyao Li, Ajay L Chandgude, Qiang Zheng, Alexander Dömling

Beilstein J Org Chem· April 2024

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Corrigendum to "Novel spirooxindole based benzimidazole scaffold: In vitro, nanoformulation and in vivo studies on anticancer and antimetastatic activity of breast adenocarcinoma" [Bioorg. Chem. 129 (2022) 106124].
Assem Barakat, Saeed Alshahrani, Abdullah Mohammed Al-Majid, Abdullah Saleh Alamary, Matti Haukka

Bioorg Chem· February 2024

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Corrigendum to "Molecular hybridization design and synthesis of novel spirooxindole-based MDM2 inhibitors endowed with BCL2 signaling attenuation; a step towards the next generation p53 activators" [Bioorg. Chem. 117 (2021) 105427].
Gehad Lotfy, Yasmine M Abdel Aziz, Mohamed M Said, El Sayed H El Ashry, El Sayed H El Tamany

Bioorg Chem· February 2024

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Exploring Phthalimide as the Acid Component in the Passerini Reaction.
Jingyao Li, Qiang Zheng, Alexander Dömling

Org Lett· February 2024

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Novel SK channel positive modulators prevent ferroptosis and excitotoxicity in neuronal cells.
Yuequ Zhang, Shabnam Shaabani, Kirsty Vowinkel, Marina Trombetta-Lima, Angélica María Sabogal-Guáqueta

Biomed Pharmacother· February 2024

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Molecular regulators of exercise-mediated insulin sensitivity in non-obese individuals.
Shamma Almuraikhy, Asmaa Doudin, Alexander Domling, Asmaa Ali J F Althani, Mohamed A Elrayess

J Cell Mol Med· January 2024

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Crystal Clear: Decoding Isocyanide Intermolecular Interactions through Crystallography.
Eleftheria Chatziorfanou, Atilio Reyes Romero, Lotfi Chouchane, Alexander Dömling

J Org Chem· January 2024

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Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery.
Zefeng Wang, Shabnam Shaabani, Xiang Gao, Yuen Lam Dora Ng, Valeriia Sapozhnikova

Nat Commun· December 2023

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Correction: Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment.
Fatma B Rashidi, Alanod D Al-Qahtani, Sara S Bashraheel, Shabnam Shaabani, Matthew R Groves

PLoS One· November 2023

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Impact of Moderate Physical Activity on Inflammatory Markers and Telomere Length in Sedentary and Moderately Active Individuals with Varied Insulin Sensitivity.
Shamma Almuraikhy, Maha Sellami, Hadaia Saleh Al-Amri, Alexander Domling, Asmaa A Althani

J Inflamm Res· November 2023

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Author Correction: The isocyanide S2 reaction.
Pravin Patil, Qiang Zheng, Katarzyna Kurpiewska, Alexander Dömling

Nat Commun· October 2023

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The isocyanide S2 reaction.
Pravin Patil, Qiang Zheng, Katarzyna Kurpiewska, Alexander Dömling

Nat Commun· September 2023

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Antioxidative Stress Metabolic Pathways in Moderately Active Individuals.
Shamma Almuraikhy, Najeha Anwardeen, Asmma Doudin, Maha Sellami, Alexander Domling

Metabolites· August 2023

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Design, Synthesis, and Biological Evaluation of 2-Hydroxy-4-phenylthiophene-3-carbonitrile as PD-L1 Antagonist and Its Comparison to Available Small Molecular PD-L1 Inhibitors.
Marta A Ważyńska, Roberto Butera, Marta Requesens, Annechien Plat, Tryfon Zarganes-Tzitzikas

J Med Chem· July 2023

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