Publications by authors named "Alexander Duval"

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SOX9 drives a stem-like transcriptional state and platinum resistance in high-grade serous ovarian cancer.
Alexander J Duval, Fidan Seker-Polat, Magdalena Rogozinska, Meric Kinali, Ann E Walts

J Clin Invest· October 2025

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Systematic comparison and base-editing-mediated directed protein evolution and functional screening yield superior auxin-inducible degron technology.
De Xing, Tao Bai, Ozlem Neyisci, Seyedeh Zahra Paylakhi, Alexander J Duval

Nat Commun· July 2025

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Comparative analysis and directed protein evolution yield an improved degron technology with minimal basal degradation, rapid inducible depletion, and faster recovery of target proteins.
Mazhar Adli, De Xing, Tao Bai, Ozlem Neyisci, Seyedehzahra Paylakhi, Alexander Duval

Res Sq· November 2024

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Integrating leiomyoma genetics, epigenomics, and single-cell transcriptomics reveals causal genetic variants, genes, and cell types.
Kadir Buyukcelebi, Alexander J Duval, Fatih Abdula, Hoda Elkafas, Fidan Seker-Polat

Nat Commun· February 2024

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Biology-driven therapy advances in high-grade serous ovarian cancer.
Yinu Wang, Alexander James Duval, Mazhar Adli, Daniela Matei

J Clin Invest· January 2024

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Engineered MED12 mutations drive leiomyoma-like transcriptional and metabolic programs by altering the 3D genome compartmentalization.
Kadir Buyukcelebi, Xintong Chen, Fatih Abdula, Hoda Elkafas, Alexander James Duval

Nat Commun· July 2023

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Engineered MED12 mutations drive uterine fibroid-like transcriptional and metabolic programs by altering the 3D genome compartmentalization.
Kadir Buyukcelebi, Xintong Chen, Fatih Abdula, Alexander Duval, Harun Ozturk

Res Sq· February 2023

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A Rapid Method for Direct Quantification of Antibody Binding-Site Concentration in Serum.
Erwin G Abucayon, Connor Whalen, Oscar B Torres, Alexander J Duval, Agnieszka Sulima

ACS Omega· August 2022

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Chemotherapy-Induced Distal Enhancers Drive Transcriptional Programs to Maintain the Chemoresistant State in Ovarian Cancer.
Stephen Shang, Jiekun Yang, Amir A Jazaeri, Alexander James Duval, Turan Tufan

Cancer Res· September 2019

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A rapid solution-based method for determining the affinity of heroin hapten-induced antibodies to heroin, its metabolites, and other opioids.
Oscar B Torres, Alexander J Duval, Agnieszka Sulima, Joshua F G Antoline, Arthur E Jacobson

Anal Bioanal Chem· June 2018

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