Publications by authors named "Alexander F Markham"

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AgileMultiIdeogram: Rapid Identification and Visualization of Autozygous Regions Using Illumina Short-Read Sequencing Data.
Christopher M Watson, Carolina Lascelles, Morag Raynor, Marilena Elpidorou, Ummey Hany, Alexander F Markham

Biology (Basel)· June 2025

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A Single Short 'Tone Burst' Results in Optimal Drug Delivery to Tumours Using Ultrasound-Triggered Therapeutic Microbubbles.
Nicola Ingram, Laura E McVeigh, Radwa H Abou-Saleh, Damien V B Batchelor, Paul M Loadman, Alexander F Markham

Pharmaceutics· March 2022

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Targeted microbubbles carrying lipid-oil-nanodroplets for ultrasound-triggered delivery of the hydrophobic drug, combretastatin A4.
Antonia Charalambous, Victoria Mico, Laura E McVeigh, Gemma Marston, Nicola Ingram, Alexander F Markham

Nanomedicine· August 2021

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Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and toxicity in normal tissues.
Nicola Ingram, Laura E McVeigh, Radwa H Abou-Saleh, Juliana Maynard, Sally A Peyman, Alexander F Markham

Theranostics· May 2021

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Reduction in the resident intestinal myelomonocytic cell population occurs during mouse intestinal tumorigenesis.
Olusola O Faluyi, Mark A Hull, Alexander F Markham, Constanze Bonifer, P Louise Coletta

Oncol Lett· April 2021

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Exploring High Aspect Ratio Gold Nanotubes as Cytosolic Agents: Structural Engineering and Uptake into Mesothelioma Cells.
Sunjie Ye, Arsalan A Azad, Joseph E Chambers, Alison J Beckett, Lucien Roach, Alexander F Markham

Small· November 2020

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Freeze-Dried Therapeutic Microbubbles: Stability and Gas Exchange.
Radwa H Abou-Saleh, Aileen Delaney, Nicola Ingram, Damien V B Batchelor, Benjamin R G Johnson, Alexander F Markham

ACS Appl Bio Mater· November 2020

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CD105 is a prognostic marker and valid endothelial target for microbubble platforms in cholangiocarcinoma.
Amit Nair, Nicola Ingram, Eldo T Verghese, Imeshi Wijetunga, Alexander F Markham

Cell Oncol (Dordr)· October 2020

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Sub-Nanometer Thick Gold Nanosheets as Highly Efficient Catalysts.
Sunjie Ye, Andy P Brown, Ashley C Stammers, Neil H Thomson, Jin Wen, Alexander F Markham

Adv Sci (Weinh)· November 2019

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Increased Sensitivity of Diagnostic Mutation Detection by Re-analysis Incorporating Local Reassembly of Sequence Reads.
Christopher M Watson, Nick Camm, Laura A Crinnion, Samuel Clokie, Rachel L Robinson, Alexander F Markham

Mol Diagn Ther· December 2017

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Characterization and Genomic Localization of a SMAD4 Processed Pseudogene.
Christopher M Watson, Nick Camm, Laura A Crinnion, Agne Antanaviciute, Julian Adlard, Alexander F Markham

J Mol Diagn· November 2017

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m6aViewer: software for the detection, analysis, and visualization of -methyladenosine peaks from mA-seq/ME-RIP sequencing data.
Agne Antanaviciute, Belinda Baquero-Perez, Christopher M Watson, Sally M Harrison, Carolina Lascelles, Alexander F Markham

RNA· October 2017

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A tubulin alpha 8 mouse knockout model indicates a likely role in spermatogenesis but not in brain development.
Christine P Diggle, Isabel Martinez-Garay, Zoltan Molnar, Martin H Brinkworth, Ed White, Alexander F Markham

PLoS One· September 2017

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Paracrine cyclooxygenase-2 activity by macrophages drives colorectal adenoma progression in the Apc mouse model of intestinal tumorigenesis.
Mark A Hull, Richard J Cuthbert, C W Stanley Ko, Daniel J Scott, Elizabeth J Cartwright, Alexander F Markham

Sci Rep· July 2017

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Evaluation of lipid-stabilised tripropionin nanodroplets as a delivery route for combretastatin A4.
Victoria Mico, Antonia Charalambous, Sally A Peyman, Radwa H Abou-Saleh, Alexander F Markham

Int J Pharm· June 2017

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The influence of intercalating perfluorohexane into lipid shells on nano and microbubble stability.
Radwa H Abou-Saleh, Sally A Peyman, Benjamin R G Johnson, Gemma Marston, Nicola Ingram, Alexander F Markham

Soft Matter· September 2016

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One-step fabrication of hollow-channel gold nanoflowers with excellent catalytic performance and large single-particle SERS activity.
Sunjie Ye, Felix Benz, May C Wheeler, Joseph Oram, Jeremy J Baumberg, Alexander F Markham

Nanoscale· August 2016

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Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy.
Christine P Diggle, Stacey J Sukoff Rizzo, Michael Popiolek, Reetta Hinttala, Jan-Philip Schülke, Alexander F Markham

Am J Hum Genet· April 2016

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Mutations in TSPAN12 Cause Autosomal-Dominant Familial Exudative Vitreoretinopathy.
James A Poulter, Manir Ali, David F Gilmour, Aine Rice, Hiroyuki Kondo, Alexander F Markham

Am J Hum Genet· March 2016

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On-chip preparation of nanoscale contrast agents towards high-resolution ultrasound imaging.
Sally A Peyman, James R McLaughlan, Radwa H Abou-Saleh, Gemma Marston, Benjamin R G Johnson, Alexander F Markham

Lab Chip· February 2016

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OVA: integrating molecular and physical phenotype data from multiple biomedical domain ontologies with variant filtering for enhanced variant prioritization.
Agne Antanaviciute, Christopher M Watson, Sally M Harrison, Carolina Lascelles, Laura Crinnion, Alexander F Markham

Bioinformatics· December 2015

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HACE1 deficiency causes an autosomal recessive neurodevelopmental syndrome.
Ronja Hollstein, David A Parry, Lisa Nalbach, Clare V Logan, Tim M Strom, Alexander F Markham

J Med Genet· December 2015

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Primary Hypertrophic Osteoarthropathy: An Update on Patient Features and Treatment.
Gabriella Giancane, Christine P Diggle, Elizabeth G Legger, Janneke Tekstra, Berent Prakken, Alexander F Markham

J Rheumatol· November 2015

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Rapid Detection of Rare Deleterious Variants by Next Generation Sequencing with Optional Microarray SNP Genotype Data.
Christopher M Watson, Laura A Crinnion, Juliana Gurgel-Gianetti, Sally M Harrison, Catherine Daly, Alexander F Markham

Hum Mutat· September 2015

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GeneTIER: prioritization of candidate disease genes using tissue-specific gene expression profiles.
Agne Antanaviciute, Catherine Daly, Laura A Crinnion, Alexander F Markham, Christopher M Watson

Bioinformatics· August 2015

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