Publications by authors named "Alexander Gasch"

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Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere.
Julius Bogomolovas, Jennifer R Fleming, Barbara Franke, Bruno Manso, Bernd Simon, Alexander Gasch

EMBO Rep· October 2021

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Skeletal Muscle Anti-Atrophic Effects of Leucine Involve Myostatin Inhibition.
André Cruz, Andrea Ferian, Paula K N Alves, William Jose Silva, Mirella Ribeiro Bento, Alexander Gasch

DNA Cell Biol· November 2020

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Expression of MuRF1 or MuRF2 is essential for the induction of skeletal muscle atrophy and dysfunction in a murine pulmonary hypertension model.
Thanh Nguyen, T Scott Bowen, Antje Augstein, Antje Schauer, Alexander Gasch

Skelet Muscle· April 2020

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Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients.
Yuta Higashikuse, Nishant Mittal, Takuro Arimura, Sung Han Yoon, Mayumi Oda, Alexander Gasch

Dis Model Mech· November 2019

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Small-molecule-mediated chemical knock-down of MuRF1/MuRF2 and attenuation of diaphragm dysfunction in chronic heart failure.
Volker Adams, T Scott Bowen, Sarah Werner, Peggy Barthel, Christina Amberger, Alexander Gasch

J Cachexia Sarcopenia Muscle· October 2019

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Small-molecule inhibition of MuRF1 attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia.
Thomas Scott Bowen, Volker Adams, Sarah Werner, Tina Fischer, Paulien Vinke, Alexander Gasch

J Cachexia Sarcopenia Muscle· December 2017

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Cardiac specific titin N2B exon is a novel sensitive serological marker for cardiac injury.
Julius Bogomolovas, Alexander Gasch, Vilhelmas Bajoras, Dovilė Karčiauskaitė, Pranas Šerpytis

Int J Cardiol· June 2016

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Titin kinase is an inactive pseudokinase scaffold that supports MuRF1 recruitment to the sarcomeric M-line.
Julijus Bogomolovas, Alexander Gasch, Felix Simkovic, Daniel J Rigden, Siegfried Labeit

Open Biol· May 2014

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Molecular basis for the fold organization and sarcomeric targeting of the muscle atrogin MuRF1.
Barbara Franke, Alexander Gasch, Dayté Rodriguez, Mohamed Chami, Muzamil M Khan

Open Biol· March 2014

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Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors.
Muzamil Majid Khan, Siegfried Strack, Franziska Wild, Akira Hanashima, Alexander Gasch

Autophagy· January 2014

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Regulation of nicotinic acetylcholine receptor turnover by MuRF1 connects muscle activity to endo/lysosomal and atrophy pathways.
Rüdiger Rudolf, Julius Bogomolovas, Siegfried Strack, Kyeong-Rok Choi, Muzamil Majid Khan, Alexander Gasch

Age (Dordr)· October 2013

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Titin-actin interaction: PEVK-actin-based viscosity in a large animal.
Charles S Chung, Julius Bogomolovas, Alexander Gasch, Carlos G Hidalgo, Siegfried Labeit

J Biomed Biotechnol· April 2012

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Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF.
Cameron D Mackereth, Tobias Madl, Sophie Bonnal, Bernd Simon, Katia Zanier, Alexander Gasch

Nature· July 2011

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Induction of MuRF1 is essential for TNF-alpha-induced loss of muscle function in mice.
Volker Adams, Norman Mangner, Alexander Gasch, Christian Krohne, Stephan Gielen

J Mol Biol· December 2008

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MuRF1-dependent regulation of systemic carbohydrate metabolism as revealed from transgenic mouse studies.
Stephanie Hirner, Christian Krohne, Alexander Schuster, Sigrid Hoffmann, Stephanie Witt, Alexander Gasch

J Mol Biol· June 2008

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Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis.
Suguru Koyama, Shoji Hata, Christian C Witt, Yasuko Ono, Stefanie Lerche, Alexander Gasch

J Mol Biol· March 2008

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Structural and biochemical characterization of the yeast exosome component Rrp40.
Anna Oddone, Esben Lorentzen, Jerome Basquin, Alexander Gasch, Vladimir Rybin

EMBO Rep· January 2007

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The structure of Prp40 FF1 domain and its interaction with the crn-TPR1 motif of Clf1 gives a new insight into the binding mode of FF domains.
Alexander Gasch, Silke Wiesner, Pau Martin-Malpartida, Ximena Ramirez-Espain, Lidia Ruiz

J Biol Chem· January 2006

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A dual parameter FRET probe for measuring PKC and PKA activity in living cells.
Justin Brumbaugh, Andreas Schleifenbaum, Alexander Gasch, Michael Sattler, Carsten Schultz

J Am Chem Soc· January 2006

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Genetically encoded FRET probe for PKC activity based on pleckstrin.
Andreas Schleifenbaum, Gunter Stier, Alexander Gasch, Michael Sattler, Carsten Schultz

J Am Chem Soc· September 2004

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