Publications by authors named "Alexander Helm"

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Induction of Cytoplasmic dsDNA and cGAS-STING Immune Signaling After Exposure of Breast Cancer Cells to X-ray or High-Energetic Carbon Ions.
Cristina Totis, Nicole B Averbeck, Burkhard Jakob, Maik Schork, Gaia Volpi, Alexander Helm

Adv Radiat Oncol· June 2025

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GMP compliant simplified fast and high yielding automated synthesis of [F]fallypride without the need of HPLC purification.
Ammar Alfteimi, Yi Zhao, Ulf Lützen, Alexander Helm, Michael Jüptner

EJNMMI Radiopharm Chem· May 2025

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FLASH Bragg-Peak Irradiation With a Therapeutic Carbon Ion Beam: First In Vivo Results.
Walter Tinganelli, Anggraeini Puspitasari-Kokko, Olga Sokol, Alexander Helm, Palma Simoniello

Int J Radiat Oncol Biol Phys· April 2025

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Particle Beam Radiobiology Status and Challenges: A PTCOG Radiobiology Subcommittee Report.
Reem Ahmad, Amelia Barcellini, Kilian Baumann, Malte Benje, Tamara Bender, Alexander Helm

Int J Part Ther· September 2024

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Carbon Ion and Photon Radiation Therapy Show Enhanced Antitumoral Therapeutic Efficacy With Neoantigen RNA-LPX Vaccines in Preclinical Colon Carcinoma Models.
Nadja Salomon, Alexander Helm, Abderaouf Selmi, Claudia Fournier, Mustafa Diken

Int J Radiat Oncol Biol Phys· July 2024

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High-LET charged particles: radiobiology and application for new approaches in radiotherapy.
Alexander Helm, Claudia Fournier

Strahlenther Onkol· December 2023

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Immune checkpoint inhibitors and Carbon iON radiotherapy In solid Cancers with stable disease (ICONIC).
Stefano Cavalieri, Viviana Vitolo, Amelia Barcellini, Sara Ronchi, Angelica Facoetti, Alexander Helm

Future Oncol· January 2023

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FLASH with carbon ions: Tumor control, normal tissue sparing, and distal metastasis in a mouse osteosarcoma model.
Walter Tinganelli, Uli Weber, Anggraeini Puspitasari, Palma Simoniello, Amir Abdollahi, Alexander Helm

Radiother Oncol· October 2022

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Automated synthesis of [Ga]Ga-FAPI-46 without pre-purification of the generator eluate on three common synthesis modules and two generator types.
Ammar Alfteimi, Ulf Lützen, Alexander Helm, Michael Jüptner, Marlies Marx

EJNMMI Radiopharm Chem· July 2022

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A simple, reliable and accurate approach for assessing [I]-capsule activity leading to significant reduction of radiation exposure of medical staff during radioiodine therapy.
Maaz Zuhayra, Alexander Helm, Joshua Ranjan, Michael Jüptner, Yi Zhao

Phys Med· April 2022

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Particle radiotherapy and molecular therapies: mechanisms and strategies towards clinical applications.
Alexander Helm, Claudia Fournier, Marco Durante

Expert Rev Mol Med· February 2022

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A Combination of Cabozantinib and Radiation Does Not Lead to an Improved Growth Control of Tumors in a Preclinical 4T1 Breast Cancer Model.
Norman Reppingen, Alexander Helm, Laura Doleschal, Marco Durante, Claudia Fournier

Front Oncol· December 2021

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In Reply to Elmali et al.
Alexander Helm, Walter Tinganelli, Claudia Fournier, Palma Simoniello, Fuki Kurosawa

Int J Radiat Oncol Biol Phys· April 2021

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Reduction of Lung Metastases in a Mouse Osteosarcoma Model Treated With Carbon Ions and Immune Checkpoint Inhibitors.
Alexander Helm, Walter Tinganelli, Palma Simoniello, Fuki Kurosawa, Claudia Fournier

Int J Radiat Oncol Biol Phys· February 2021

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Hibernation and Radioprotection: Gene Expression in the Liver and Testicle of Rats Irradiated under Synthetic Torpor.
Walter Tinganelli, Timna Hitrec, Fabrizio Romani, Palma Simoniello, Fabio Squarcio, Alexander Helm

Int J Mol Sci· January 2019

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Combining Heavy-Ion Therapy with Immunotherapy: An Update on Recent Developments.
Alexander Helm, Daniel K Ebner, Walter Tinganelli, Palma Simoniello, Alessandra Bisio

Int J Part Ther· September 2018

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Advances in Radiation Biology of Particle Irradiation.
Alexander Helm, Walter Tinganelli, Marco Durante

Prog Tumor Res· April 2018

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Heart in space: effect of the extraterrestrial environment on the cardiovascular system.
Richard L Hughson, Alexander Helm, Marco Durante

Nat Rev Cardiol· March 2018

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The Immunoregulatory Potential of Particle Radiation in Cancer Therapy.
Daniel K Ebner, Walter Tinganelli, Alexander Helm, Alessandra Bisio, Shigeru Yamada

Front Immunol· February 2017

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Hibernation for space travel: Impact on radioprotection.
Matteo Cerri, Walter Tinganelli, Matteo Negrini, Alexander Helm, Emanuele Scifoni

Life Sci Space Res (Amst)· November 2016

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The Influence of C-Ions and X-rays on Human Umbilical Vein Endothelial Cells.
Alexander Helm, Ryonfa Lee, Marco Durante, Sylvia Ritter

Front Oncol· February 2016

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Ionizing Radiation Impacts on Cardiac Differentiation of Mouse Embryonic Stem Cells.
Alexander Helm, Onetsine Arrizabalaga, Diana Pignalosa, Insa S Schroeder, Marco Durante

Stem Cells Dev· January 2016

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