Publications by authors named "Alexander Leithner"

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Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency.
Alexander Leithner, Oskar Staufer, Tanmay Mitra, Falk Liberta, Salvatore Valvo

Proc Natl Acad Sci U S A· June 2025

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Transmembrane domain-driven PD-1 dimers mediate T cell inhibition.
Elliot A Philips, Jia Liu, Audun Kvalvaag, Alexander M Mørch, Anna S Tocheva, Alexander Leithner

Sci Immunol· March 2024

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En-Face Imaging of T Cell-Dendritic Cell Immunological Synapses.
Alexander Leithner, Jack Merrin, Michael Sixt

Methods Mol Biol· May 2023

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Type 1 piliated uropathogenic hijack the host immune response by binding to CD14.
Kathrin Tomasek, Alexander Leithner, Ivana Glatzova, Michael S Lukesch, Calin C Guet

Elife· July 2022

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WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues.
Florian Gaertner, Patricia Reis-Rodrigues, Ingrid de Vries, Miroslav Hons, Juan Aguilera, Alexander Leithner

Dev Cell· January 2022

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Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse.
Alexander Leithner, Lukas M Altenburger, Robert Hauschild, Frank P Assen, Klemens Rottner

J Cell Biol· April 2021

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Fast and efficient genetic engineering of hematopoietic precursor cells for the study of dendritic cell migration.
Alexander Leithner, Joerg Renkawitz, Ingrid De Vries, Robert Hauschild, Hans Häcker

Eur J Immunol· June 2018

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Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells.
Miroslav Hons, Aglaja Kopf, Robert Hauschild, Alexander Leithner, Florian Gaertner

Nat Immunol· June 2018

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Dendritic Cells Interpret Haptotactic Chemokine Gradients in a Manner Governed by Signal-to-Noise Ratio and Dependent on GRK6.
Jan Schwarz, Veronika Bierbaum, Kari Vaahtomeri, Robert Hauschild, Markus Brown, Alexander Leithner

Curr Biol· May 2017

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Locally Triggered Release of the Chemokine CCL21 Promotes Dendritic Cell Transmigration across Lymphatic Endothelia.
Kari Vaahtomeri, Markus Brown, Robert Hauschild, Ingrid De Vries, Alexander Franz Leithner

Cell Rep· May 2017

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Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes.
Alexander Leithner, Alexander Eichner, Jan Müller, Anne Reversat, Markus Brown

Nat Cell Biol· November 2016

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