Publications by authors named "Alexander Meijer"

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Proteolytic signatures of coagulation identified by plasma peptidomics.
Jessica Del Castillo Alferez, Alette Kooiker, Floris P J van Alphen, Carmen van der Zwaan, Herm-Jan Brinkman, Joost C M Meijers, Alexander B Meijer

J Thromb Haemost· August 2025

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The TNFα-binding domain of the therapeutic antibody adalimumab elicits CD4 T-cell responses in rheumatoid arthritis patients.
Mateusz Makuch, Josine van Beek, Carla A Wijbrandts, Marja Aalbers, Philippe Stas, Alexander B Meijer

Front Immunol· July 2025

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Plasma proteomics in patients with von Willebrand disease and hemophilia A highlights von Willebrand factor as main determinant of response to desmopressin treatment.
Jessica Del Castillo Alferez, Eva R Smit, Alexander B Meijer, Karin Fijnvandraat, Marieke J H A Kruip

Res Pract Thromb Haemost· March 2025

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Integrative phosphoproteomic analyses reveal hemostatic-endothelial signaling interplay.
Stijn A Groten, Bart L van den Eshof, Floris P J van Alphen, Alexander B Meijer, Maartje van den Biggelaar

J Thromb Haemost· February 2025

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Plasma Profiling of Acute Myeloid Leukemia With Fever- and Infection-Related Complications During Chemotherapy-Induced Neutropenia.
Iris C Kreft, Annemarie van de Geer, Eva R Smit, Carmen van der Zwaan, Floris P J van Alphen, Alexander B Meijer

Cancer Rep (Hoboken)· October 2024

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Variant mapping using mass spectrometry-based proteotyping as a diagnostic tool in von Willebrand disease.
Iris C Kreft, Tirsa T van Duijl, Calvin van Kwawegen, Ferdows Atiq, Winny Phan, Alexander B Meijer

J Thromb Haemost· July 2024

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Platelet proteomic profiling in sitosterolemia suggests thrombocytopenia is driven by lipid disorder and not platelet aberrations.
Jessica Del Castillo, Anton T J Tool, Karin van Leeuwen, Floris P J van Alphen, Marion M Brands, Alexander B Meijer

Blood Adv· May 2024

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Multi-omics delineation of cytokine-induced endothelial inflammatory states.
Stijn A Groten, Eva R Smit, Esmée F J Janssen, Bart L van den Eshof, Floris P J van Alphen, Alexander B Meijer

Commun Biol· May 2023

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Mass spectrometry-based analysis on the impact of whole blood donation on the global plasma proteome.
Iris C Kreft, Arie J Hoogendijk, Carmen van der Zwaan, Floris P J van Alphen, Mariette Boon-Spijker, Alexander B Meijer

Transfusion· March 2023

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Proteomic landscapes of inherited platelet disorders with different etiologies.
Iris C Kreft, Elise J Huisman, Marjon H Cnossen, Floris P J van Alphen, Carmen van der Zwaan, Alexander B Meijer

J Thromb Haemost· February 2023

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Nanobodies against factor XI apple 3 domain inhibit binding of factor IX and reveal a novel binding site for high molecular weight kininogen.
Awital Bar Barroeta, J Arnoud Marquart, Kamran Bakhtiari, Alexander B Meijer, Rolf T Urbanus, Joost C M Meijers

J Thromb Haemost· November 2022

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SYMPHONY consortium: Orchestrating personalized treatment for patients with bleeding disorders.
Marjon H Cnossen, Iris van Moort, Simone H Reitsma, Moniek P M de Maat, Roger E G Schutgens, Karina Meijer, Alexander B Meijer

J Thromb Haemost· June 2022

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Neutrophil azurophilic granule glycoproteins are distinctively decorated by atypical pauci- and phosphomannose glycans.
Karli R Reiding, Yu-Hsien Lin, Floris P J van Alphen, Alexander B Meijer, Albert J R Heck

Commun Biol· August 2021

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Probing activation-driven changes in coagulation factor IX by mass spectrometry.
Nadia Freato, Floris P J van Alphen, Mariëtte Boon-Spijker, Maartje van den Biggelaar, Alexander B Meijer

J Thromb Haemost· June 2021

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Hydrogen-Deuterium Exchange Mass Spectrometry Identifies Activated Factor IX-Induced molecular Changes in Activated Factor VIII.
Josse van Galen, Nadia Freato, Małgorzata A Przeradzka, Eduard H T M Ebberink, Mariëtte Boon-Spijker, Alexander B Meijer

Thromb Haemost· May 2021

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Simulation-Based and Experimental Investigation of Micro End Mills with Wiper Geometry.
Timo Platt, Alexander Meijer, Torben Merhofe, Dirk Biermann

Micromachines (Basel)· April 2021

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Neutrophil specific granule and NETosis defects in gray platelet syndrome.
Cathelijn E M Aarts, Kate Downes, Arie J Hoogendijk, Evelien G G Sprenkeler, Roel P Gazendam, Saskia M C Langemeijer, Alexander B Meijer

Blood Adv· January 2021

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Factor VIII-driven changes in activated factor IX explored by hydrogen-deuterium exchange mass spectrometry.
Nadia Freato, Eduard H T M Ebberink, Josse van Galen, Caroline Fribourg, Mariëtte Boon-Spijker, Alexander B Meijer

Blood· December 2020

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Flow-induced Reorganization of Laminin-integrin Networks Within the Endothelial Basement Membrane Uncovered by Proteomics.
Eelke P Béguin, Esmée F J Janssen, Mark Hoogenboezem, Alexander B Meijer, Arie J Hoogendijk

Mol Cell Proteomics· July 2020

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D' domain region Arg782-Cys799 of von Willebrand factor contributes to factor VIII binding.
Małgorzata A Przeradzka, Josse van Galen, Eduard H T M Ebberink, Arie J Hoogendijk, Carmen van der Zwaan, Alexander B Meijer

Haematologica· June 2020

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Unique surface-exposed hydrophobic residues in the C1 domain of factor VIII contribute to cofactor function and von Willebrand factor binding.
Małgorzata A Przeradzka, Nadia Freato, Mariëtte Boon-Spijker, Josse van Galen, Carmen van der Zwaan, Alexander B Meijer

J Thromb Haemost· February 2020

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Missing regions within the molecular architecture of human fibrin clots structurally resolved by XL-MS and integrative structural modeling.
Oleg Klykov, Carmen van der Zwaan, Albert J R Heck, Alexander B Meijer, Richard A Scheltema

Proc Natl Acad Sci U S A· January 2020

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Hydrogen-deuterium exchange mass spectrometry highlights conformational changes induced by factor XI activation and binding of factor IX to factor XIa.
Awital Bar Barroeta, Josse van Galen, Ingrid Stroo, J Arnoud Marquart, Alexander B Meijer, Joost C M Meijers

J Thromb Haemost· December 2019

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Activated neutrophils exert myeloid-derived suppressor cell activity damaging T cells beyond repair.
Cathelijn E M Aarts, Ida H Hiemstra, Eelke P Béguin, Arjan J Hoogendijk, Souhailla Bouchmal, Alexander B Meijer

Blood Adv· November 2019

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Dynamic Transcriptome-Proteome Correlation Networks Reveal Human Myeloid Differentiation and Neutrophil-Specific Programming.
Arie J Hoogendijk, Farzin Pourfarzad, Cathelijn E M Aarts, Anton T J Tool, Ida H Hiemstra, Alexander B Meijer

Cell Rep· November 2019

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