Publications by authors named "Alexander Miethke"

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Outcomes of Fontan patients undergoing combined heart-liver transplantation in pediatric hospitals across the United States.
Grant Chappell, Amir Mehdizadeh-Shrifi, Darren Turner, Alexander Bondoc, Suzanne Evans, Alexander G Miethke

J Thorac Cardiovasc Surg· January 2026

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Allosensitization From Blood Transfusion in Pediatric Solid Organ Transplant Candidates: Impact of Irradiation.
Corinne M Hite, Kyle A Merrill, Clifford Chin, Don Hayes, Alexander G Miethke

Pediatr Transplant· January 2026

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Bile acids engage the SIPR-STAT3 signaling axis to modulate regulatory T cell responses in fibrosing cholangiopathies.
Ramesh Kudira, Zi F Yang, Immaculeta Osuji, Michelle S M A Damen, Annika Yang Vom Hofe, Alexander G Miethke

J Hepatol· November 2025

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A new multisystem ERCC1-hepatorenal syndrome: insights from a clinical cohort, molecular pathogenesis, and management guidelines.
Susan M White, Annelotte P Wondergem, Isa Breet, Maren Dittmaier, Katrina Bell, Alexander G Miethke

Eur J Hum Genet· October 2025

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Prospective Multicenter Longitudinal Measurement of Liver Stiffness in School-Age Children With Cholestatic Liver Disease.
Benjamin L Shneider, Nathan P Goodrich, Wen Ye, Jean P Molleston, Daniel H Leung, Alexander G Miethke

Gastro Hep Adv· October 2025

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Interleukin 8-CXCR2-mediated neutrophil extracellular trap formation in biliary atresia associated with neutrophil extracellular trap-induced stellate cell activation.
Yuhuan Luo, Lisa Fraser, Julia Jezykowski, Nitika A Gupta, Alexander G Miethke

Hepatology· September 2025

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Longitudinal, Multicenter Study of Clinical Factors Impacting Health-Related Quality of Life in Pediatric Autoimmune Liver Disease.
Rebecca Farr, Cyd Castro Rojas, Mosab Alquraish, Kevin Hommel, Rashmi Sahay, Alexander Miethke

medRxiv· August 2025

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Macrophages drive a fibrogenic gene program of periductal fibroblasts in pediatric primary sclerosing cholangitis.
Yunguan Wang, David Adeleke, Xiangfei Xie, Zi Yang, Annika Yang von Hofe, Alexander G Miethke

bioRxiv· August 2025

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Pediatric endoscopic ultrasound-guided liver biopsy: 3-year experience.
Talia S Schwartz, Marialena Mouzaki, Lara Berklite, Oscar F Lopez-Nunez, Alexander Miethke

J Pediatr Gastroenterol Nutr· May 2025

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Magnetic resonance cholangiopancreatography for suspected cholangiopathy in children and young adults: a multi-reader agreement study.
Pradipta Debnath, Nadeen K Abu Ata, Joseph Y Cao, Shailee V Lala, Archana Malik, Alexander G Miethke

Pediatr Radiol· March 2025

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Quantitative fibrosis identifies biliary tract involvement and is associated with outcomes in pediatric autoimmune liver disease.
Leticia Khendek, Cyd Castro-Rojas, Constance Nelson, Mosab Alquraish, Rebekah Karns, Alexander G Miethke

Hepatol Commun· January 2025

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DNAJB1-PKAc Kinase Is Expressed in Young Patients with Pediatric Liver Cancers and Enhances Carcinogenic Pathways.
Yasmeen Fleifil, Ruhi Gulati, Katherine Jennings, Alexander Miethke, Alexander Bondoc

Cancers (Basel)· December 2024

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Gucy1α1 specifically marks kidney, heart, lung and liver fibroblasts.
Valeria Rudman-Melnick, Davy Vanhoutte, Kaitlynn Stowers, Michelle Sargent, Mike Adam, Alexander G Miethke

Sci Rep· November 2024

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Gucy1α1 specifically marks kidney, heart, lung and liver fibroblasts.
Valeria Rudman-Melnick, Davy Vanhoutte, Kaitlynn Stowers, Michelle Sargent, Mike Adam, Alexander G Miethke

Res Sq· August 2024

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Association Between MR Elastography Liver Stiffness and Histologic Liver Fibrosis in Children and Young Adults With Autoimmune Liver Disease.
Jonathan R Dillman, Andrew T Trout, Amy E Taylor, Leticia Khendek, Jennifer L Kasten, Alexander G Miethke

AJR Am J Roentgenol· July 2024

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Maralixibat in progressive familial intrahepatic cholestasis (MARCH-PFIC): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.
Alexander G Miethke, Adib Moukarzel, Gilda Porta, Joshue Covarrubias Esquer, Piotr Czubkowski

Lancet Gastroenterol Hepatol· July 2024

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Liver disease and transplantation in telomere biology disorders: An international multicenter cohort.
YunZu Michele Wang, Batul Kaj-Carbaidwala, Adam Lane, Suneet Agarwal, Fabian Beier, Alexander G Miethke

Hepatol Commun· July 2024

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Gucy1α1 specifically marks kidney, heart, lung and liver fibroblasts.
Valeria Rudman-Melnick, Davy Vanhoutte, Kaitlynn Stowers, Michelle Sargent, Mike Adam, Alexander G Miethke

bioRxiv· May 2024

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Cholestasis alters polarization and suppressor function of hepatic regulatory T cells.
Ramesh Kudira, Zi F Yang, Immaculeta Osuji, Rebekah Karns, Priya Bariya, Alexander Gerhard Miethke

bioRxiv· May 2024

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Red cell abnormalities characterized by ektacytometry in children with cholestasis.
Theodore S Kocoshis, Theodosia A Kalfa, Alexander G Miethke, William F Balistreri, Katie G Seu

Pediatr Res· March 2024

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Case Report: Childhood Erythrocytosis due to Hypermanganesemia Caused by Homozygous Mutation.
Tiziana Coppola, Hannah Hughes, Paul Finch, Joshua Hess, Steve Wu, Alexander G Miethke

Front Hematol· March 2024

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Accessible chromatin maps of inflammatory bowel disease intestine nominate cell-type mediators of genetic disease risk.
Joseph A Wayman, Zi Yang, Elizabeth Angerman, Erin Bonkowski, Ingrid Jurickova, Alexander G Miethke

bioRxiv· February 2024

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Deleterious variants in TNFAIP3 are associated with type II and seronegative pediatric autoimmune hepatitis.
Sindhu Pandurangi, Astha Malik, Joshua Owens, C Alexander Valencia, Alexander G Miethke

J Hepatol· January 2024

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Protein biomarkers GDF15 and FGF21 to differentiate mitochondrial hepatopathies from other pediatric liver diseases.
Johan L K Van Hove, Marisa W Friederich, Dana K Strode, Roxanne A Van Hove, Kristen R Miller, Alexander G Miethke

Hepatol Commun· January 2024

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Sarcopenia is associated with osteopenia and impaired quality of life in children with genetic intrahepatic cholestatic liver disease.
Julia M Boster, Nathan P Goodrich, Cathie Spino, Kathleen M Loomes, Estella M Alonso, Alexander Miethke

Hepatol Commun· November 2023

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