Publications by authors named "Alexander Partin"

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Onboard, tethered IL-12 boosts potency of the Tmod NOT gate and preserves selectivity.
Jingli A Zhang, Sara Imboden, Dongwoo Lee, Alexandre Zampieri, Sanam Shafaattalab, Alexander Partin

J Immunother Cancer· May 2025

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Data imbalance in drug response prediction: multi-objective optimization approach in deep learning setting.
Oleksandr Narykov, Yitan Zhu, Thomas Brettin, Yvonne A Evrard, Alexander Partin

Brief Bioinform· March 2025

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The Hallmarks of Predictive Oncology.
Akshat Singhal, Xiaoyu Zhao, Patrick Wall, Emily So, Guido Calderini, Alexander Partin

Cancer Discov· February 2025

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Geometric parameters that affect the behavior of logic-gated CAR T cells.
Alexander C Partin, Richele Bruno, Sanam Shafaattalab, Erica Vander Mause, Aaron Winters

Front Immunol· February 2024

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A Comprehensive Investigation of Active Learning Strategies for Conducting Anti-Cancer Drug Screening.
Priyanka Vasanthakumari, Yitan Zhu, Thomas Brettin, Alexander Partin, Maulik Shukla

Cancers (Basel)· January 2024

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Integration of Computational Docking into Anti-Cancer Drug Response Prediction Models.
Oleksandr Narykov, Yitan Zhu, Thomas Brettin, Yvonne A Evrard, Alexander Partin

Cancers (Basel)· December 2023

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Data augmentation and multimodal learning for predicting drug response in patient-derived xenografts from gene expressions and histology images.
Alexander Partin, Thomas Brettin, Yitan Zhu, James M Dolezal, Sara Kochanny

Front Med (Lausanne)· March 2023

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AI-accelerated protein-ligand docking for SARS-CoV-2 is 100-fold faster with no significant change in detection.
Austin Clyde, Xuefeng Liu, Thomas Brettin, Hyunseung Yoo, Alexander Partin

Sci Rep· February 2023

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Deep learning methods for drug response prediction in cancer: Predominant and emerging trends.
Alexander Partin, Thomas S Brettin, Yitan Zhu, Oleksandr Narykov, Austin Clyde

Front Med (Lausanne)· February 2023

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Protocol for high-throughput cloning, expression, purification, and evaluation of bispecific antibodies.
Danqing Li, Alexander C Partin, Liangjun Zhao, Irwin Chen, Mark L Michaels

STAR Protoc· June 2022

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A cross-study analysis of drug response prediction in cancer cell lines.
Fangfang Xia, Jonathan Allen, Prasanna Balaprakash, Thomas Brettin, Cristina Garcia-Cardona, Alexander Partin

Brief Bioinform· January 2022

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Pandemic drugs at pandemic speed: infrastructure for accelerating COVID-19 drug discovery with hybrid machine learning- and physics-based simulations on high-performance computers.
Agastya P Bhati, Shunzhou Wan, Dario Alfè, Austin R Clyde, Mathis Bode, Alexander Partin

Interface Focus· December 2021

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Publisher Correction: Converting tabular data into images for deep learning with convolutional neural networks.
Yitan Zhu, Thomas Brettin, Fangfang Xia, Alexander Partin, Maulik Shukla

Sci Rep· July 2021

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Enhancing the Prefusion Conformational Stability of SARS-CoV-2 Spike Protein Through Structure-Guided Design.
Timothy P Riley, Hui-Ting Chou, Ruozhen Hu, Krzysztof P Bzymek, Ana R Correia, Alexander C Partin

Front Immunol· May 2021

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Learning curves for drug response prediction in cancer cell lines.
Alexander Partin, Thomas Brettin, Yvonne A Evrard, Yitan Zhu, Hyunseung Yoo

BMC Bioinformatics· May 2021

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Converting tabular data into images for deep learning with convolutional neural networks.
Yitan Zhu, Thomas Brettin, Fangfang Xia, Alexander Partin, Maulik Shukla

Sci Rep· May 2021

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Ensemble transfer learning for the prediction of anti-cancer drug response.
Yitan Zhu, Thomas Brettin, Yvonne A Evrard, Alexander Partin, Fangfang Xia

Sci Rep· October 2020

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Enhanced Co-Expression Extrapolation (COXEN) Gene Selection Method for Building Anti-Cancer Drug Response Prediction Models.
Yitan Zhu, Thomas Brettin, Yvonne A Evrard, Fangfang Xia, Alexander Partin

Genes (Basel)· September 2020

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Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA.
Alexander C Partin, Kaiming Zhang, Byung-Cheon Jeong, Emily Herrell, Shanshan Li

Mol Cell· May 2020

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RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Tri D Ngo, Alexander C Partin, Yunsun Nam

Cell Rep· December 2019

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Publisher Correction: Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs.
Alexander C Partin, Tri D Ngo, Emily Herrell, Byung-Cheon Jeong, Gary Hon

Nat Commun· September 2018

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Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs.
Alexander C Partin, Tri D Ngo, Emily Herrell, Byung-Cheon Jeong, Gary Hon

Nat Commun· November 2017

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Preconditioning-induced CXCL12 upregulation minimizes leukocyte infiltration after stroke in ischemia-tolerant mice.
Uma Maheswari Selvaraj, Sterling B Ortega, Ruilong Hu, Robert Gilchrist, Xiangmei Kong, Alexander Partin

J Cereb Blood Flow Metab· March 2017

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Shear wave dispersion in lean versus steatotic rat livers.
Christopher T Barry, Christopher Hazard, Zaegyoo Hah, Gang Cheng, Alexander Partin

J Ultrasound Med· June 2015

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What do we know about shear wave dispersion in normal and steatotic livers?
Kevin J Parker, Alexander Partin, Deborah J Rubens

Ultrasound Med Biol· May 2015

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