Publications by authors named "Alexander Pushkin"

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CryoEM and computational modeling structural insights into the pH regulator NBCn1.
Weiguang Wang, Hristina R Zhekova, Kirill Tsirulnikov, B Sridhar Dwadasi, Ehecatl Guzman Aparicio, Alexander Pushkin

Nat Commun· November 2025

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On the substrate turnover rate of NBCe1 and AE1 SLC4 transporters: structure-function considerations.
Alexander Pushkin, Liyo Kao, Hristina R Zhekova, Rustam Azimov, Natalia Abuladze

Front Physiol· January 2025

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Molecular dynamics simulations of lipid-protein interactions in SLC4 proteins.
Hristina R Zhekova, Daniel P Ramirez Echemendía, Besian I Sejdiu, Alexander Pushkin, D Peter Tieleman

Biophys J· June 2024

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Coarse-grained molecular dynamics simulations of lipid-protein interactions in SLC4 proteins.
Hristina R Zhekova, Daniel P Ramirez-Echemendía, Besian I Sejdiu, Alexander Pushkin, D Peter Tieleman

bioRxiv· June 2023

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CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations.
Hristina R Zhekova, Jiansen Jiang, Weiguang Wang, Kirill Tsirulnikov, Gülru Kayık, Alexander Pushkin

Commun Biol· December 2022

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Publisher Correction: Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE.
Weiguang Wang, Kirill Tsirulnikov, Hristina R Zhekova, Gülru Kayık, Hanif Muhammad Khan, Alexander Pushkin

Nat Commun· October 2021

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Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE.
Weiguang Wang, Kirill Tsirulnikov, Hristina R Zhekova, Gülru Kayık, Hanif Muhammad Khan, Alexander Pushkin

Nat Commun· September 2021

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Identification of multiple substrate binding sites in SLC4 transporters in the outward-facing conformation: Insights into the transport mechanism.
Hristina R Zhekova, Alexander Pushkin, Gülru Kayık, Liyo Kao, Rustam Azimov

J Biol Chem· August 2021

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SLC4A11 function: evidence for H(OH) and NH-H transport.
Liyo Kao, Rustam Azimov, Xuesi M Shao, Natalia Abuladze, Debra Newman, Alexander Pushkin

Am J Physiol Cell Physiol· February 2020

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CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1.
Kevin W Huynh, Jiansen Jiang, Natalia Abuladze, Kirill Tsirulnikov, Liyo Kao, Alexander Pushkin

Nat Commun· March 2018

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Aminoacylase 3 Is a New Potential Marker and Therapeutic Target in Hepatocellular Carcinoma.
Kirill Tsirulnikov, Sergio Duarte, Anamika Ray, Nakul Datta, Ali Zarrinpar, Alexander Pushkin

J Cancer· January 2018

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Single particle electron microscopy analysis of the bovine anion exchanger 1 reveals a flexible linker connecting the cytoplasmic and membrane domains.
Jiansen Jiang, Nathaniel Magilnick, Kirill Tsirulnikov, Natalia Abuladze, Ivo Atanasov, Alexander Pushkin

PLoS One· August 2013

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Aminoacylase 3 binds to and cleaves the N-terminus of the hepatitis C virus core protein.
Kirill Tsirulnikov, Natalia Abuladze, Ritu Vahi, Huma Hasnain, Martin Phillips, Alexander Pushkin

FEBS Lett· November 2012

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Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal.
Kirill Tsirulnikov, Natalia Abuladze, Anatol Bragin, Kym Faull, Duilio Cascio, Alexander Pushkin

Toxicol Appl Pharmacol· September 2012

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Structural and functional characterization of the C-terminal transmembrane region of NBCe1-A.
Quansheng Zhu, Liyo Kao, Rustam Azimov, Natalia Abuladze, Debra Newman, Alexander Pushkin

J Biol Chem· November 2010

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Structures of aminoacylase 3 in complex with acetylated substrates.
Jennifer M Hsieh, Kirill Tsirulnikov, Michael R Sawaya, Nathaniel Magilnick, Natalia Abuladze, Alexander Pushkin

Proc Natl Acad Sci U S A· October 2010

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Transport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2).
Kirill Tsirulnikov, Natalia Abuladze, Myong-Chul Koag, Debra Newman, Karoline Scholz, Alexander Pushkin

Toxicol Appl Pharmacol· April 2010

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Topological location and structural importance of the NBCe1-A residues mutated in proximal renal tubular acidosis.
Quansheng Zhu, Liyo Kao, Rustam Azimov, Debra Newman, Weixin Liu, Alexander Pushkin

J Biol Chem· April 2010

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Slc4a11 gene disruption in mice: cellular targets of sensorineuronal abnormalities.
Ivan A Lopez, Mark I Rosenblatt, Charles Kim, Gary C Galbraith, Sherri M Jones, Alexander Pushkin

J Biol Chem· September 2009

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Mouse aminoacylase 3: a metalloenzyme activated by cobalt and nickel.
Kirill Tsirulnikov, Natalia Abuladze, Debra Newman, Sergey Ryazantsev, Talya Wolak, Alexander Pushkin

Biochim Biophys Acta· July 2009

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NBCe1-A Transmembrane Segment 1 Lines the Ion Translocation Pathway.
Quansheng Zhu, Rustam Azimov, Liyo Kao, Debra Newman, Weixin Liu, Alexander Pushkin

J Biol Chem· March 2009

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G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis.
Rustam Azimov, Natalia Abuladze, Pakan Sassani, Debra Newman, Liyo Kao, Alexander Pushkin

Am J Physiol Renal Physiol· September 2008

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Oligomeric structure and minimal functional unit of the electrogenic sodium bicarbonate cotransporter NBCe1-A.
Liyo Kao, Pakan Sassani, Rustam Azimov, Alexander Pushkin, Natalia Abuladze

J Biol Chem· September 2008

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Measurement of aminoacylases.
Alexander Pushkin, Ira Kurtz

Curr Protoc Toxicol· February 2008

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Structural characterization of dimeric murine aminoacylase III.
Sergey Ryazantsev, Natalia Abuladze, Debra Newman, Galyna Bondar, Ira Kurtz, Alexander Pushkin

FEBS Lett· May 2007

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