Publications by authors named "Alexander R A Anderson"

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Directed Evolution Restored Castrate Sensitivity in a Patient With Castrate Resistant Metastatic Prostate Cancer.
Robert A Gatenby, Alexander R A Anderson, Joel S Brown, Jill Gallaher, Jeffrey Krolick

Prostate· December 2025

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Mathematical Oncology: How Modeling Is Transforming Clinical Decision-Making.
Kevin R Scibilia, Kit Gallagher, M A Masud, Mark Robertson-Tessi, Chandler D Gatenbee, Alexander R A Anderson

Cancer Res· December 2025

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Distinct Tumor-Immune Ecologies in Lung Cancer Patients Predict Progression and Define a Clinical Biomarker of Therapy Response.
Sandhya Prabhakaran, Chandler D Gatenbee, Mark Robertson-Tessi, Zarifa Gahramanli Ozturk, Theresa A Boyle, Alexander R A Anderson

Cancer Res· December 2025

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Deriving Optimal Treatment Timing for Adaptive Therapy: Matching the Model to the Tumor Dynamics.
Kit Gallagher, Maximilian A R Strobl, Alexander R A Anderson, Philip K Maini

Bull Math Biol· September 2025

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Evolutionary Double-Bind Treatment Using Radiation Therapy and Natural Killer Cell-Based Immunotherapy in Prostate Cancer.
Kimberly A Luddy, Jeffrey West, Mark Robertson-Tessi, Bina Desai, Andrew Ojeda, Alexander R A Anderson

Int J Radiat Oncol Biol Phys· September 2025

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Evolutionary antifragile therapy.
Jeffrey West, Bina Desai, Maximilian Strobl, Jill Gallaher, Mark Robertson-Tessi, Alexander R A Anderson

bioRxiv· September 2025

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The role of environmentally mediated drug resistance in facilitating the spatial distribution of residual disease.
Amy Milne, Andriy Marusyk, Philip K Maini, Alexander R A Anderson, Noemi Picco

Commun Biol· August 2025

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PSA/testosterone ratio as a potential biomarker to identify early progressors of adaptive therapy in metastatic castration sensitive prostate cancer.
Jill A Gallaher, Robert A Gatenby, Joel S Brown, Alexander R A Anderson, Jingsong Zhang

medRxiv· May 2025

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Deriving Optimal Treatment Timing for Adaptive Therapy: Matching the Model to the Tumor Dynamics.
Kit Gallagher, Maximilian A R Strobl, Alexander R A Anderson, Philip K Maini

medRxiv· April 2025

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Multifactorial stroma-mediated resistance is a major contributor to residual disease under targeted therapies in lung cancers.
Bina Desai, Tatiana Miti, Sandhya Prabhakaran, Daria Miroshnychenko, Menkara Henry, Alexander R A Anderson

Res Sq· April 2025

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Oncolytic immunotherapy with nivolumab in muscle-invasive bladder cancer: a phase 1b trial.
Roger Li, Nancy Y Villa, Xiaoqing Yu, Joseph O Johnson, Gustavo Borjas, Alexander R A Anderson

Nat Med· January 2025

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Correction: Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy.
Kit Gallagher, Maximilian A R Strobl, Derek S Park, Fabian C Spoendlin, Robert A Gatenby, Alexander R A Anderson

Cancer Res· January 2025

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Study protocol for Adaptive ChemoTherapy for Ovarian cancer (ACTOv): a multicentre phase II randomised controlled trial to evaluate the efficacy of adaptive therapy (AT) with carboplatin, based on changes in CA125, in patients with relapsed platinum-sensitive high-grade serous or high-grade endometrioid ovarian cancer.
Uma Anne Mukherjee, Helen Hockings, Nicholas Counsell, Apini Patel, Priya Narayanan, Alexander R A Anderson

BMJ Open· December 2024

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The ACROBAT 2022 challenge: Automatic registration of breast cancer tissue.
Philippe Weitz, Masi Valkonen, Leslie Solorzano, Circe Carr, Kimmo Kartasalo, Alexander R A Anderson

Med Image Anal· October 2024

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Modeling tumors as complex ecosystems.
Guim Aguadé-Gorgorió, Alexander R A Anderson, Ricard Solé

iScience· September 2024

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A novel combination therapy for ER+ breast cancer suppresses drug resistance via an evolutionary double-bind.
Rena Emond, Jeffrey West, Vince Grolmusz, Patrick Cosgrove, Aritro Nath, Alexander R A Anderson

bioRxiv· September 2024

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Spatial interactions modulate tumor growth and immune infiltration.
Sadegh Marzban, Sonal Srivastava, Sharon Kartika, Rafael Bravo, Rachel Safriel, Alexander R A Anderson

NPJ Syst Biol Appl· September 2024

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Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy.
Kit Gallagher, Maximilian A R Strobl, Derek S Park, Fabian C Spoendlin, Robert A Gatenby, Alexander R A Anderson

Cancer Res· June 2024

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To modulate or to skip: De-escalating PARP inhibitor maintenance therapy in ovarian cancer using adaptive therapy.
Maximilian A R Strobl, Alexandra L Martin, Jeffrey West, Jill Gallaher, Mark Robertson-Tessi, Alexander R A Anderson

Cell Syst· June 2024

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Modeling tumors as species-rich ecological communities.
Guim Aguadé-Gorgorió, Alexander R A Anderson, Ricard Solé

bioRxiv· April 2024

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Peristromal niches protect lung cancers from targeted therapies through a combined effect of multiple molecular mediators.
Bina Desai, Tatiana Miti, Sandhya Prabhakaran, Daria Miroshnychenko, Menkara Henry, Alexander R A Anderson

bioRxiv· April 2024

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Tumor-immune metaphenotypes orchestrate an evolutionary bottleneck that promotes metabolic transformation.
Jeffrey West, Frederika Rentzeperis, Casey Adam, Rafael Bravo, Kimberly A Luddy, Alexander R A Anderson

Front Immunol· March 2024

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Second-Order Effects of Chemotherapy Pharmacodynamics and Pharmacokinetics on Tumor Regression and Cachexia.
Luke Pierik, Patricia McDonald, Alexander R A Anderson, Jeffrey West

Bull Math Biol· March 2024

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Testing Adaptive Therapy Protocols Using Gemcitabine and Capecitabine in a Preclinical Model of Endocrine-Resistant Breast Cancer.
Sareh Seyedi, Ruthanne Teo, Luke Foster, Daniel Saha, Lida Mina, Karen S Anderson, Alexander R A Anderson

Cancers (Basel)· January 2024

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Testing Adaptive Therapy Protocols using Gemcitabine and Capecitabine on a Mouse Model of Endocrine-Resistant Breast Cancer.
Sareh Seyedi, Ruthanne Teo, Luke Foster, Daniel Saha, Lida Mina, Karen S Anderson, Alexander R A Anderson

bioRxiv· September 2023

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