Publications by authors named "Alexander Reiner"

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Association between neutrophil to lymphocyte ratio and Alzheimer's disease in large biobank cohorts.
Emily Drzymalla, Christy Avery, Priya Palta, Alexander P Reiner, Quan Sun

J Alzheimers Dis· December 2025

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Epigenome-wide association study of nuclear DNA methylation in relation to mitochondrial heteroplasmy.
Meng Lai, Kyeezu Kim, Yinan Zheng, Christina A Castellani, Scott M Ratliff, Alexander P Reiner

Nat Commun· December 2025

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Genetic architecture and analysis practices of circulating metabolites in the NHLBI Trans-Omics for Precision Medicine Program.
Nannan Wang, Franklin P Ockerman, Laura Y Zhou, Megan L Grove, Taryn Alkis, Alexander P Reiner

Am J Hum Genet· November 2025

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Plasma p-tau217 and incident mild cognitive impairment and dementia in older women: 25-year prospective study in The Women's Health Initiative Memory Study.
Aladdin H Shadyab, Bowei Zhang, Andrea Z LaCroix, Michelle M Mielke, Susan M Resnick, Alexander P Reiner

medRxiv· November 2025

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Human plasma proteomic profile of clonal hematopoiesis.
Zhi Yu, Amélie Vromman, Ngoc Quynh H Nguyen, Art Schuermans, Linke Li, Alexander P Reiner

Nat Commun· November 2025

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Clonal Hematopoiesis and Cardiovascular Outcomes in Older Women.
Daniel Ezzat, Md Mesbah Uddin, Liying Xue, Yash Pershad, Shengruo Zhang, Alexander P Reiner

J Am Coll Cardiol· October 2025

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Clonal hematopoiesis of indeterminate potential and the risk of cognitive impairment in the Women's Health Initiative Memory Study.
Yasminka A Jakubek, Aaron P Smith, Xiaoyan I Leng, Megan E Hall, Daniel Ezzat, Alexander P Reiner

Alzheimers Dement· October 2025

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Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Roelof A J Smit, Kaitlin H Wade, Qin Hui, Joshua D Arias, Xianyong Yin, Alexander P Reiner

Nat Med· September 2025

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Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program.
Chloé Sarnowski, Yixin Zhang, Farah Ammous, Lincoln M P Shade, Daniel DiCorpo, Alexander P Reiner

Commun Biol· September 2025

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Correlates and consequences of clonal hematopoiesis expansion rate: a 16-year longitudinal study of 6976 women.
Yash Pershad, Md Mesbah Uddin, Liying Xue, Jeffrey Haessler, Jason M Collins, Alexander P Reiner

Blood· August 2025

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Compartment-Specific Metabolic Alterations to Insulin Reflect Adiposity-Driven Variation and Predict Type 2 Diabetes.
Magdalena Sevilla-González, Paul A Hanson, Jesse Islam, Sarah Hsu, Michael A Tsoukas, Alexander P Reiner

J Clin Endocrinol Metab· August 2025

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Whole-genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia.
Runjia Li, Sarah A Gagliano Taliun, Kevin Liao, Matthew Flickinger, Janet L Sobell, Alexander P Reiner

HGG Adv· August 2025

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An Efficient Lasso Framework for Admixture-Aware Polygenic Scores.
Franklin Ockerman, Brian Chen, Quan Sun, Elena V Kharitonova, Walter Chen, Alexander Reiner

bioRxiv· August 2025

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Protein quantitative trait locus analysis in African American and non-Hispanic White individuals.
Yanwei Cai, Mari Johnson, Jeffrey Haessler, Aaron J Molstad, Shih-Jen Hwang, Alexander P Reiner

Genome Biol· July 2025

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Mosaic Loss of Y chromosome associates with lung function, emphysema and epigenetic aging.
Woei-Yuh Saw, Kangjin Kim, Yichen Huang, Jeong H Yun, Xiaolong Ma, Alexander P Reiner

medRxiv· July 2025

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Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.
Alicia Huerta-Chagoya, Joohyun Kim, Ravi Mandla, Yingchang Lu, Ken Suzuki, Alexander P Reiner

medRxiv· July 2025

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EndoPRS: Incorporating endophenotype information to improve polygenic risk scores for clinical endpoints-A study in asthma.
Elena V Kharitonova, Quan Sun, Franklin Ockerman, Brian Chen, Laura Y Zhou, Alexander P Reiner

Am J Hum Genet· May 2025

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Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits.
Lauren E Petty, Hung-Hsin Chen, Elizabeth G Frankel, Wanying Zhu, Carolina G Downie, Alexander P Reiner

Nat Commun· April 2025

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Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.
Xinruo Zhang, Jennifer A Brody, Mariaelisa Graff, Heather M Highland, Nathalie Chami, Alexander P Reiner

Nat Commun· April 2025

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Clinical progression of clonal hematopoiesis is determined by a combination of mutation timing, fitness, and clonal structure.
Eric Latorre-Crespo, Neil A Robertson, E Gozde Kosebent, Louise MacGillivray, Lee Murphy, Alexander P Reiner

bioRxiv· March 2025

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Genetic drivers and clinical consequences of mosaic chromosomal alterations in 1 million individuals.
Kun Zhao, Yash Pershad, Hannah M Poisner, Xiaolong Ma, Kali Quade, Alexander P Reiner

medRxiv· March 2025

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A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies.
Xihao Li, Han Chen, Margaret Sunitha Selvaraj, Eric Van Buren, Hufeng Zhou, Alexander P Reiner

Nat Comput Sci· February 2025

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Cross-Ancestry Comparison of Aptamer and Antibody Proteomics Measures.
Jayna C Nicholas, Daniel H Katz, Usman A Tahir, Catherine L Debban, Francois Aguet, Alexander P Reiner

Res Sq· February 2025

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Regulation of protein abundance in normal human tissues.
Huaying Fang, Lihua Jiang, Felipe da Veiga Leprevost, Ruiqi Jian, Joanne Chan, Alexander P Reiner

medRxiv· January 2025

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Correlates and Consequences of Clonal Hematopoiesis Expansion Rate: A 15-Year Longitudinal Study of 6,986 Women.
Yash Pershad, Md Mesbah Uddin, Liying Xue, Jeffrey Haessler, Jason M Collins, Alexander P Reiner

medRxiv· January 2025

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