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Publications by authors named "Alexander Safrygin"

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Three-component Castagnoli-Cushman reaction with ammonium acetate delivers 2-unsubstituted isoquinol-1-ones as potent inhibitors of poly(ADP-ribose) polymerase (PARP).
Alexander Safrygin, Petr Zhmurov, Dmitry Dar'in, Sergey Silonov, Mariia Kasatkina

J Enzyme Inhib Med Chem· December 2021


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1-Oxo-3,4-dihydroisoquinoline-4-carboxamides as novel druglike inhibitors of poly(ADP-ribose) polymerase (PARP) with favourable ADME characteristics.
Alexander Safrygin, Petr Zhmurov, Dmitry Dar'in, Sergey Silonov, Mariia Kasatkina

J Enzyme Inhib Med Chem· December 2021


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Exploration of the nitrogen heterocyclic periphery around the core of the advanced FFA1 agonist fasiglifam (TAK-875).
Alexey Lukin, Anna Bakholdina, Nikolay Zhurilo, Oleksandra Onopchenko, Elena Zhuravel, Alexander Safrygin

Arch Pharm (Weinheim)· April 2021


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