Publications by authors named "Alexander Scheffold"

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Butyrophilin 3A/2A1-independent activation of human Vγ9Vδ2 γδ T cells by bacteria.
Daniel Gombert, Jara Simeonov, Katharina Klein, Sophie Agaugué, Alexander Scheffold

PNAS Nexus· November 2025

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Frequency of synaptic antigen-specific CD4 T cells in dementia is age-dependent but not correlated with cognitive impairment.
Julius Hoffmann, Marie-Luise Machule, Jakob Kreye, Laura Stöffler, Péter Körtvelyessy, Alexander Scheffold

Immun Ageing· June 2025

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Detection and Characterisation of Wasp Venom-Specific T Cells Using the ARTE Method in Allergic Patients.
Magdalena Kraft, Samira Saleh, Guido Heine, Alexander Scheffold, Petra Bacher

Clin Exp Allergy· May 2025

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Integrin αVβ6: Autoantigen and Driver of Epithelial Remodeling in Colon and Bile Ducts in Primary Sclerosing Cholangitis and Inflammatory Bowel Disease.
Dominik Roth, Miriam M Düll, Ludwig J Horst, Aylin Lindemann, Xenia Malzer, Alexander Scheffold

J Crohns Colitis· February 2025

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The role of allergen-specific regulatory T cells in the control of allergic disease.
Athanasios Stoumpos, Guido Heine, Carina Saggau, Alexander Scheffold

Curr Opin Immunol· February 2025

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Autoantigen-specific CD4 T cells acquire an exhausted phenotype and persist in human antigen-specific autoimmune diseases.
Carina Saggau, Petra Bacher, Daniela Esser, Mahdi Rasa, Silja Meise, Alexander Scheffold

Immunity· October 2024

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Preschool-age children maintain a distinct memory CD4 T cell and memory B cell response after SARS-CoV-2 infection.
Benoît Manfroi, Bui Thi Cuc, Aurélien Sokal, Alexis Vandenberghe, Sarah Temmam, Alexander Scheffold

Sci Transl Med· September 2024

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Author Correction: c-Maf-dependent T cell control of intestinal T17 cells and IgA establishes host-microbiota homeostasis.
Christian Neumann, Jonas Blume, Urmi Roy, Peggy P Teh, Ajithkumar Vasanthakumar, Alexander Scheffold

Nat Immunol· July 2024

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Advancing evolutionary medicine in Northern Germany: Collaboration between Kiel University's Medical Faculty and the Max Planck Institute for Evolutionary Biology.
John F Baines, Claudia D Baldus, Frederic Bertels, Monika Brüggemann, Christoph Kaleta, Alexander Scheffold

Evol Med Public Health· July 2024

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T-cell subsets in allergy and tolerance induction.
Ina Suhrkamp, Alexander Scheffold, Guido Heine

Eur J Immunol· October 2023

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Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic T1 cell responses in Crohn's disease.
Gabriela Rios Martini, Ekaterina Tikhonova, Elisa Rosati, Meghan Bialt DeCelie, Laura Katharina Sievers, Alexander Scheffold

Nat Med· October 2023

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Proliferative activity of antigen-specific CD154+ T cells against bacterial and fungal respiratory pathogens in cystic fibrosis decreases after initiation of highly effective CFTR modulator therapy.
Patience N Eschenhagen, Petra Bacher, Claudia Grehn, Jochen G Mainz, Alexander Scheffold

Front Pharmacol· June 2023

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Antigen specificity and cross-reactivity drive functionally diverse anti-Aspergillus fumigatus T cell responses in cystic fibrosis.
Carsten Schwarz, Patience Eschenhagen, Henrijette Schmidt, Thordis Hohnstein, Christina Iwert, Alexander Scheffold

J Clin Invest· March 2023

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A novel unconventional T cell population enriched in Crohn's disease.
Elisa Rosati, Gabriela Rios Martini, Mikhail V Pogorelyy, Anastasia A Minervina, Frauke Degenhardt, Alexander Scheffold

Gut· November 2022

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The pre-exposure SARS-CoV-2-specific T cell repertoire determines the quality of the immune response to vaccination.
Carina Saggau, Gabriela Rios Martini, Elisa Rosati, Silja Meise, Berith Messner, Alexander Scheffold

Immunity· October 2022

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Resolving SARS-CoV-2 CD4 T cell specificity via reverse epitope discovery.
Mikhail V Pogorelyy, Elisa Rosati, Anastasia A Minervina, Robert C Mettelman, Alexander Scheffold

Cell Rep Med· August 2022

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-specific CD4 T-cell scoring discriminates tuberculosis infection from disease.
Andrej Mantei, Tim Meyer, Mariana Schürmann, Christiane Beßler, Harald Bias, Alexander Scheffold

Eur Respir J· July 2022

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The metalloprotease ADAM10 generates soluble interleukin-2 receptor alpha (sCD25) in vivo.
Sophia Kirschke, Ireti Ogunsulire, Balachandar Selvakumar, Neele Schumacher, Tanya Sezin, Alexander Scheffold

J Biol Chem· June 2022

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Efficacy, T cell activation and antibody responses in accelerated Plasmodium falciparum sporozoite chemoprophylaxis vaccine regimens.
Javier Ibanez, Rolf Fendel, Freia-Raphaella Lorenz, Patricia Granados-Bayon, Sina Brückner, Alexander Scheffold

NPJ Vaccines· May 2022

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The role of A Disintegrin and Metalloproteinase (ADAM)-10 in T helper cell biology.
Tanya Sezin, Balachandar Selvakumar, Alexander Scheffold

Biochim Biophys Acta Mol Cell Res· April 2022

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A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4 T cells and is defective in Crohn´s disease patients.
Jonas Ahlers, Andrej Mantei, Laura Lozza, Manuela Stäber, Frederik Heinrich, Alexander Scheffold

Mucosal Immunol· March 2022

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Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition).
Andrea Cossarizza, Hyun-Dong Chang, Andreas Radbruch, Sergio Abrignani, Richard Addo, Alexander Scheffold

Eur J Immunol· December 2021

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Characterization of SARS-CoV-2 public CD4+ αβ T cell clonotypes through reverse epitope discovery.
Elisa Rosati, Mikhail V Pogorelyy, Anastasia A Minervina, Alexander Scheffold, Andre Franke

bioRxiv· November 2021

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Decreased inflammatory cytokine production of antigen-specific CD4 T cells in NMDA receptor encephalitis.
Le-Minh Dao, Marie-Luise Machule, Petra Bacher, Julius Hoffmann, Lam-Thanh Ly, Alexander Scheffold

J Neurol· June 2021

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Flow Cytometric Characterization of Human Antigen-Reactive T-Helper Cells.
Carina Saggau, Alexander Scheffold, Petra Bacher

Methods Mol Biol· June 2021

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