Publications by authors named "Alexander Sparrow"

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Nutraceuticals silybin B, resveratrol, and epigallocatechin-3 gallate-bind to cardiac muscle troponin to restore the loss of lusitropy caused by cardiomyopathy mutations , , and .
Zeyu Yang, Alice M Sheehan, Andrew E Messer, Sharmane Tsui, Alexander Sparrow

Front Physiol· December 2024

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Comparing the effects of chemical Ca dyes and R-GECO on contractility and Ca transients in adult and human iPSC cardiomyocytes.
Paul Robinson, Alexander J Sparrow, Yiangos Psaras, Violetta Steeples, Jillian N Simon

J Mol Cell Cardiol· July 2023

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CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.
Yiangos Psaras, Francesca Margara, Marcelo Cicconet, Alexander J Sparrow, Giuliana G Repetti

Circ Res· July 2021

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Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia.
Lucia M Moreira, Abhijit Takawale, Mohit Hulsurkar, David A Menassa, Agne Antanaviciute, Alexander J Sparrow

Nature· November 2020

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Dilated cardiomyopathy mutations in thin-filament regulatory proteins reduce contractility, suppress systolic Ca, and activate NFAT and Akt signaling.
Paul Robinson, Alexander J Sparrow, Suketu Patel, Marta Malinowska, Svetlana N Reilly

Am J Physiol Heart Circ Physiol· August 2020

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Mavacamten rescues increased myofilament calcium sensitivity and dysregulation of Ca flux caused by thin filament hypertrophic cardiomyopathy mutations.
Alexander J Sparrow, Hugh Watkins, Matthew J Daniels, Charles Redwood, Paul Robinson

Am J Physiol Heart Circ Physiol· March 2020

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Measurement of Myofilament-Localized Calcium Dynamics in Adult Cardiomyocytes and the Effect of Hypertrophic Cardiomyopathy Mutations.
Alexander J Sparrow, Kolja Sievert, Suketu Patel, Yu-Fen Chang, Connor N Broyles

Circ Res· April 2019

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Hypertrophic cardiomyopathy mutations increase myofilament Ca buffering, alter intracellular Ca handling, and stimulate Ca-dependent signaling.
Paul Robinson, Xing Liu, Alexander Sparrow, Suketu Patel, Yin-Hua Zhang

J Biol Chem· July 2018

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LIM kinase function and renal growth: Potential role for LIM kinases in fetal programming of kidney development.
Alexander J Sparrow, Dylan Sweetman, Simon J M Welham

Life Sci· October 2017

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Acetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism.
Simon J M Welham, Alexander J Sparrow, David S Gardner, Matthew J Elmes

World J Nephrol· January 2017

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Excess maternal salt intake produces sex-specific hypertension in offspring: putative roles for kidney and gastrointestinal sodium handling.
Clint Gray, Emad A Al-Dujaili, Alexander J Sparrow, Sheila M Gardiner, Jim Craigon

PLoS One· June 2014

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