Publications by authors named "Alexandra A Duarte"

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MDC1 counteracts replication fork reversal and mediates chemosensitivity in BRCA1/2-deficient tumors.
Hülya Dogan, Martin Liptay, Joana S Barbosa, Ewa Gogola, Alexandra A Duarte

Oncogene· December 2025

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Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors.
Jinhyuk Bhin, Mariana Paes Dias, Ewa Gogola, Frank Rolfs, Sander R Piersma, Alexandra A Duarte

Cell Rep· May 2023

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Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.
Ewa Gogola, Alexandra A Duarte, Julian R de Ruiter, Wouter W Wiegant, Jonas A Schmid

Cancer Cell· June 2019

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Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.
Ewa Gogola, Alexandra A Duarte, Julian R de Ruiter, Wouter W Wiegant, Jonas A Schmid

Cancer Cell· June 2018

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BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance.
Alexandra A Duarte, Ewa Gogola, Norman Sachs, Marco Barazas, Stefano Annunziato

Nat Methods· February 2018

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A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity.
Norman Sachs, Joep de Ligt, Oded Kopper, Ewa Gogola, Gergana Bounova, Alexandra Alves Duarte

Cell· January 2018

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EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation.
Beatrice Rondinelli, Ewa Gogola, Hatice Yücel, Alexandra A Duarte, Marieke van de Ven

Nat Cell Biol· November 2017

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Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells.
Arnab Ray Chaudhuri, Elsa Callen, Xia Ding, Ewa Gogola, Alexandra A Duarte

Nature· November 2016

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Replication fork stability confers chemoresistance in BRCA-deficient cells.
Arnab Ray Chaudhuri, Elsa Callen, Xia Ding, Ewa Gogola, Alexandra A Duarte

Nature· July 2016

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A platinum complex that binds non-covalently to DNA and induces cell death via a different mechanism than cisplatin.
Kogularamanan Suntharalingam, Oscar Mendoza, Alexandra A Duarte, David J Mann, Ramon Vilar

Metallomics· May 2013

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A tri-copper(II) complex displaying DNA-cleaving properties and antiproliferative activity against cancer cells.
Kogularamanan Suntharalingam, Douglas J Hunt, Alexandra A Duarte, Andrew J P White, David J Mann

Chemistry· November 2012

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Heterologous expression of a Tpo1 homolog from Arabidopsis thaliana confers resistance to the herbicide 2,4-D and other chemical stresses in yeast.
Tânia R Cabrito, Miguel C Teixeira, Alexandra A Duarte, Paula Duque, Isabel Sá-Correia

Appl Microbiol Biotechnol· October 2009

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