Publications by authors named "Alexandra B Spicer"

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Ketamine or Etomidate for Tracheal Intubation of Critically Ill Adults.
Jonathan D Casey, Kevin P Seitz, Brian E Driver, Kevin W Gibbs, Adit A Ginde, Alexandra B Spicer

N Engl J Med· December 2025

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Individualised treatment effects of enhanced early mobilisation in mechanically ventilated patients: a secondary analysis of the TEAM trial.
Carol L Hodgson, Alexandra B Spicer, Tessa Broadley, Michael Bailey, Rinaldo Bellomo

Intensive Care Med· November 2025

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Multivariate protein landscape of host response in hospitalised patients with suspected infection in the emergency department.
Pratik Sinha, Alexandra B Spicer, Sivasubramanium Bhavani, Carlos López-Espina, Gregory L Watson

Nat Commun· August 2025

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Can Machine Learning Raise Early Goal-Directed Therapy From the Grave?
Alexandra B Spicer, Matthew M Churpek

Crit Care Med· January 2025

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Machine Learning-Driven Analysis of Individualized Treatment Effects Comparing Buprenorphine and Naltrexone in Opioid Use Disorder Relapse Prevention.
Majid Afshar, Emma J Graham Linck, Alexandra B Spicer, John Rotrosen, Elizabeth M Salisbury-Afshar

J Addict Med· October 2024

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Subgroup analyses and heterogeneity of treatment effects in randomized trials: a primer for the clinician.
Alexandra B Spicer, Alexandre B Cavalcanti, Fernando G Zampieri

Curr Opin Crit Care· October 2024

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Individualized Treatment Effects of Oxygen Targets in Mechanically Ventilated Critically Ill Adults.
Kevin G Buell, Alexandra B Spicer, Jonathan D Casey, Kevin P Seitz, Edward T Qian

JAMA· April 2024

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Analysis of Protein Biomarkers From Hospitalized COVID-19 Patients Reveals Severity-Specific Signatures and Two Distinct Latent Profiles With Differential Responses to Corticosteroids.
Philip A Verhoef, Alexandra B Spicer, Carlos Lopez-Espina, Akhil Bhargava, Lee Schmalz

Crit Care Med· December 2023

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Development and external validation of multimodal postoperative acute kidney injury risk machine learning models.
George K Karway, Jay L Koyner, John Caskey, Alexandra B Spicer, Kyle A Carey

JAMIA Open· December 2023

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Regulation of metabolic health by dietary histidine in mice.
Victoria Flores, Alexandra B Spicer, Michelle M Sonsalla, Nicole E Richardson, Deyang Yu

J Physiol· June 2023

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Individualized Treatment Effects of Bougie versus Stylet for Tracheal Intubation in Critical Illness.
Kevin P Seitz, Alexandra B Spicer, Jonathan D Casey, Kevin G Buell, Edward T Qian

Am J Respir Crit Care Med· June 2023

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Hospital-Level Variation in Death for Critically Ill Patients with COVID-19.
Matthew M Churpek, Shruti Gupta, Alexandra B Spicer, William F Parker, John Fahrenbach

Am J Respir Crit Care Med· August 2021

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Machine Learning Prediction of Death in Critically Ill Patients With Coronavirus Disease 2019.
Matthew M Churpek, Shruti Gupta, Alexandra B Spicer, Salim S Hayek, Anand Srivastava

Crit Care Explor· August 2021

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The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine.
Deyang Yu, Nicole E Richardson, Cara L Green, Alexandra B Spicer, Michaela E Murphy

Cell Metab· May 2021

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