Publications by authors named "Alexandra Benchoua"

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Role of innate immune and inflammatory signaling in West Nile virus tropism and neuronal and glial cell death.
Valentine Chaillot, François Piumi, Kamila Gorna, Noémie Berry, Jennifer Richardson, Alexandra Benchoua

Sci Rep· December 2025

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Generation of three iPSC lines from patients with CACNA1S related congenital myopathy.
Reem Bou Akar, Karine Giraud-Triboult, Lina El Kassar, Hamel Mahiou, Pascal Fragner, Alexandra Benchoua

Stem Cell Res· October 2025

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DYRK1A roles in human neural progenitors.
Jeremie Courraud, Angélique Quartier, Nathalie Drouot, Irene Zapata-Bodalo, Johan Gilet, Alexandra Benchoua

Front Neurosci· March 2025

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Pharmacological modulation of developmental and synaptic phenotypes in human SHANK3 deficient stem cell-derived neuronal models.
Amandine Thibaudeau, Karen Schmitt, Louise François, Laure Chatrousse, David Hoffmann, Alexandra Benchoua

Transl Psychiatry· June 2024

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How to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems?
Craig R G Willis, Marco Calvaruso, Debora Angeloni, Sarah Baatout, Alexandra Benchoua

NPJ Microgravity· May 2024

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An equine iPSC-based phenotypic screening platform identifies pro- and anti-viral molecules against West Nile virus.
Marielle Cochet, François Piumi, Kamila Gorna, Noémie Berry, Gaëlle Gonzalez, Alexandra Benchoua

Vet Res· March 2024

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How are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms?
Trent Davis, Kevin Tabury, Shouan Zhu, Debora Angeloni, Sarah Baatout, Alexandra Benchoua

NPJ Microgravity· February 2024

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Establishment of heterozygous and homozygous SHANK3 knockout clonal pluripotent stem cells from the parental hESC line SA001 using CRISPR/Cas9.
Laure Chatrousse, Thifaine Poullion, Lina El-Kassar, Karine Giraud-Triboult, Claire Boissart, Alexandra Benchoua

Stem Cell Res· October 2023

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How do gravity alterations affect animal and human systems at a cellular/tissue level?
Francesca Cialdai, Austin M Brown, Cory W Baumann, Debora Angeloni, Sarah Baatout, Alexandra Benchoua

NPJ Microgravity· October 2023

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CRISPR/Cas9-mediated generation of human embryonic stem cell sub-lines with HPRT1 gene knockout to model Lesch Nyhan disease.
Claire Boissart, Laure Chatrousse, Thifaine Poullion, Lina El-Kassar, Karine Giraud-Triboult, Alexandra Benchoua

Stem Cell Res· September 2023

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Identification of signaling pathways modifying human dopaminergic neuron development using a pluripotent stem cell-based high-throughput screening automated system: purinergic pathways as a proof-of-principle.
Claire Boissart, Marie Lasbareilles, Johana Tournois, Laure Chatrousse, Thifaine Poullion, Alexandra Benchoua

Front Pharmacol· June 2023

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Human Cytomegalovirus Modifies Placental Small Extracellular Vesicle Composition to Enhance Infection of Fetal Neural Cells In Vitro.
Mathilde Bergamelli, Hélène Martin, Yann Aubert, Jean-Michel Mansuy, Marlène Marcellin, Alexandra Benchoua

Viruses· September 2022

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Contribution of Human Pluripotent Stem Cell-Based Models to Drug Discovery for Neurological Disorders.
Alexandra Benchoua, Marie Lasbareilles, Johana Tournois

Cells· November 2021

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Human cytomegalovirus infection is associated with increased expression of the lissencephaly gene PAFAH1B1 encoding LIS1 in neural stem cells and congenitally infected brains.
Maude Rolland, Hélène Martin, Mathilde Bergamelli, Yann Sellier, Bettina Bessières, Alexandra Benchoua

J Pathol· May 2021

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Pathological modeling of TBEV infection reveals differential innate immune responses in human neurons and astrocytes that correlate with their susceptibility to infection.
Mazigh Fares, Marielle Cochet-Bernoin, Gaëlle Gonzalez, Claudia N Montero-Menei, Odile Blanchet, Alexandra Benchoua

J Neuroinflammation· March 2020

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Rescuing compounds for Lesch-Nyhan disease identified using stem cell-based phenotypic screening.
Valentin Ruillier, Johana Tournois, Claire Boissart, Marie Lasbareilles, Gurvan Mahé, Alexandra Benchoua

JCI Insight· February 2020

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Altered spinogenesis in iPSC-derived cortical neurons from patients with autism carrying de novo SHANK3 mutations.
Laura Gouder, Aline Vitrac, Hany Goubran-Botros, Anne Danckaert, Jean-Yves Tinevez, Alexandra Benchoua

Sci Rep· January 2019

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Genes and Pathways Regulated by Androgens in Human Neural Cells, Potential Candidates for the Male Excess in Autism Spectrum Disorder.
Angélique Quartier, Laure Chatrousse, Claire Redin, Céline Keime, Nicolas Haumesser, Alexandra Benchoua

Biol Psychiatry· August 2018

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Human Pluripotent Stem Cell-derived Cortical Neurons for High Throughput Medication Screening in Autism: A Proof of Concept Study in SHANK3 Haploinsufficiency Syndrome.
Hélène Darville, Aurélie Poulet, Frédérique Rodet-Amsellem, Laure Chatrousse, Julie Pernelle, Alexandra Benchoua

EBioMedicine· July 2016

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PPARγ Is Activated during Congenital Cytomegalovirus Infection and Inhibits Neuronogenesis from Human Neural Stem Cells.
Maude Rolland, Xiaojun Li, Yann Sellier, Hélène Martin, Teresa Perez-Berezo, Alexandra Benchoua

PLoS Pathog· April 2016

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Protein Kinase-A Inhibition Is Sufficient to Support Human Neural Stem Cells Self-Renewal.
Pauline Georges, Claire Boissart, Aurélie Poulet, Marc Peschanski, Alexandra Benchoua

Stem Cells· December 2015

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Three-dimensional Quantification of Dendritic Spines from Pyramidal Neurons Derived from Human Induced Pluripotent Stem Cells.
Laura Gouder, Jean-Yves Tinevez, Hany Goubran-Botros, Alexandra Benchoua, Thomas Bourgeron

J Vis Exp· October 2015

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Borna disease virus phosphoprotein impairs the developmental program controlling neurogenesis and reduces human GABAergic neurogenesis.
Chloé Scordel, Alexandra Huttin, Marielle Cochet-Bernoin, Marion Szelechowski, Aurélie Poulet, Alexandra Benchoua

PLoS Pathog· April 2015

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Pluripotent stem cells as a model to study non-coding RNAs function in human neurogenesis.
Alexandra Benchoua, Marc Peschanski

Front Cell Neurosci· August 2013

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mTOR-dependent proliferation defect in human ES-derived neural stem cells affected by myotonic dystrophy type 1.
Jérôme Alexandre Denis, Morgane Gauthier, Latif Rachdi, Sophie Aubert, Karine Giraud-Triboult, Alexandra Benchoua

J Cell Sci· April 2013

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