Publications by authors named "Alexandra Compagnucci"

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Assessment of the steady-state drug-drug interactions between dolutegravir and ritonavir-boosted darunavir in adolescents.
Seef Abdalla, Alexandra Compagnucci, Alasdair Bamford, Man K Chan, José T Ramos

AIDS· August 2025

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Correction: Optimising Paediatric HIV Treatment: Recent Developments and Future Directions.
Anne E M Kamphuis, Alasdair Bamford, Alfredo Tagarro, Tim R Cressey, Adrie Bekker, Alexandra Compagnucci

Paediatr Drugs· July 2025

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Optimising Paediatric HIV Treatment: Recent Developments and Future Directions.
Anne E M Kamphuis, Alasdair Bamford, Alfredo Tagarro, Tim R Cressey, Adrie Bekker, Alexandra Compagnucci

Paediatr Drugs· November 2024

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Simultaneous pharmacokinetic modeling of unbound and total darunavir with ritonavir in adolescents: a substudy of the SMILE trial.
Seef Abdalla, Alexandra Compagnucci, Yoann Riault, Man K Chan, Alasdair Bamford

Antimicrob Agents Chemother· February 2024

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Nucleoside/nucleotide reverse transcriptase inhibitor sparing regimen with once daily integrase inhibitor plus boosted darunavir is non-inferior to standard of care in virologically-suppressed children and adolescents living with HIV - Week 48 results of the randomised SMILE Penta-17-ANRS 152 clinical trial.
Alexandra Compagnucci, Man K Chan, Yacine Saïdi, Tim R Cressey, Alasdair Bamford

EClinicalMedicine· June 2023

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Population pharmacokinetics of unbound and total dolutegravir concentrations in children aged 12 years and older: a PK substudy of the SMILE trial.
Seef Abdalla, Alexandra Compagnucci, Yi Zheng, Jean-Marc Tréluyer, Yacine Saidi

J Antimicrob Chemother· April 2023

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Dolutegravir as First- or Second-Line Treatment for HIV-1 Infection in Children.
Anna Turkova, Ellen White, Hilda A Mujuru, Adeodata R Kekitiinwa, Cissy M Kityo, Alexandra Compagnucci

N Engl J Med· December 2021

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ODYSSEY clinical trial design: a randomised global study to evaluate the efficacy and safety of dolutegravir-based antiretroviral therapy in HIV-positive children, with nested pharmacokinetic sub-studies to evaluate pragmatic WHO-weight-band based dolutegravir dosing.
Cecilia L Moore, Anna Turkova, Hilda Mujuru, Adeodata Kekitiinwa, Abbas Lugemwa, Alexandra Compagnucci

BMC Infect Dis· January 2021

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Weekends-off efavirenz-based antiretroviral therapy in HIV-infected children, adolescents and young adults (BREATHER): Extended follow-up results of a randomised, open-label, non-inferiority trial.
Anna Turkova, Cecilia L Moore, Karina Butler, Alexandra Compagnucci, Yacine Saïdi

PLoS One· July 2018

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Hepatic, Renal, Hematologic, and Inflammatory Markers in HIV-Infected Children on Long-term Suppressive Antiretroviral Therapy.
Ann J Melvin, Meredith Warshaw, Alexandra Compagnucci, Yacine Saidi, Linda Harrison

J Pediatric Infect Dis Soc· September 2017

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Neurocognition and quality of life after reinitiating antiretroviral therapy in children randomized to planned treatment interruption.
Jintanat Ananworanich, Diane Melvin, Jose T R Amador, Tristan Childs, Gabriela Medin, Alexandra Compagnucci

AIDS· April 2016

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Early antiretroviral therapy in children perinatally infected with HIV: a unique opportunity to implement immunotherapeutic approaches to prolong viral remission.
Nigel Klein, Paolo Palma, Katherine Luzuriaga, Savita Pahwa, Eleni Nastouli, Alexandra Compagnucci

Lancet Infect Dis· September 2015

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HIV-1 Drug Resistance and Second-Line Treatment in Children Randomized to Switch at Low Versus Higher RNA Thresholds.
Linda Harrison, Ann Melvin, Susan Fiscus, Yacine Saidi, Eleni Nastouli, Alexandra Compagnucci

J Acquir Immune Defic Syndr· September 2015

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Pharmacokinetics of pediatric lopinavir/ritonavir tablets in children when administered twice daily according to FDA weight bands.
Diane E T Bastiaans, Silvia Forcat, Hermione Lyall, Tim R Cressey, Rawiwan Hansudewechakul, Alexandra Compagnucci

Pediatr Infect Dis J· March 2014

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Outcomes after reinitiating antiretroviral therapy in children randomized to planned treatment interruptions.
Torsak Bunupuradah, Trinh Duong, Alexandra Compagnucci, Paddy McMaster, Stefania Bernardi

AIDS· February 2013

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Adherence to antiretroviral therapy and acceptability of planned treatment interruptions in HIV-infected children.
Linda Harrison, Jintanat Ananworanich, Djamel Hamadache, Alexandra Compagnucci, Martina Penazzato

AIDS Behav· January 2013

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First-line antiretroviral therapy with a protease inhibitor versus non-nucleoside reverse transcriptase inhibitor and switch at higher versus low viral load in HIV-infected children: an open-label, randomised phase 2/3 trial.

Lancet Infect Dis· April 2011

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PENTA 2009 guidelines for the use of antiretroviral therapy in paediatric HIV-1 infection.

HIV Med· November 2009

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Pregnancy outcomes in women with HIV type-1 receiving a lopinavir/ritonavir-containing regimen.
Elie Azria, Constance Moutafoff, Thomas Schmitz, Jean Patrick Le Meaux, Anne Krivine, Alexandra Compagnucci

Antivir Ther· July 2009

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Population analysis of the pregnancy-related modifications in lopinavir pharmacokinetics and their possible consequences for dose adjustment.
Marion Bouillon-Pichault, Vincent Jullien, Elie Azria, Emmanuelle Pannier, Ghislaine Firtion, Alexandra Compagnucci

J Antimicrob Chemother· June 2009

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Plasma drug concentrations and virologic evaluations after stopping treatment with nonnucleoside reverse-transcriptase inhibitors in HIV type 1-infected children.
Tim R Cressey, Hannah Green, Saye Khoo, Jean-Marc Treluyer, Alexandra Compagnucci

Clin Infect Dis· May 2008

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A randomized controlled trial of genotypic HIV drug resistance testing in HIV-1-infected children: the PERA (PENTA 8) trial.
Hannah Green, Diana M Gibb, Alexandra Compagnucci, Vania Giacomet, Anita de Rossi

Antivir Ther· March 2007

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Bayesian parameter estimates of nelfinavir and its active metabolite, hydroxy-tert-butylamide, in infants perinatally infected with human immunodeficiency virus type 1.
Salomé Payen, Albert Faye, Alexandra Compagnucci, Carlo Giaquinto, Diana Gibbs

Antimicrob Agents Chemother· February 2005

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Persistence of multidrug-resistant HIV-1 without antiretroviral treatment 2 years after sexual transmission.
Constance Delaugerre, Laurence Morand-Joubert, Marie-Laure Chaix, Odile Picard, Anne-Genevieve Marcelin, Alexandra Compagnucci

Antivir Ther· June 2004

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Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial).
Diana M Gibb, A Sarah Walker, Steve Kaye, Anita De Rossi, Mounir Ait-Khaled, Alexandra Compagnucci

Antivir Ther· December 2002

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