Publications by authors named "Alexandra F Freeman"

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Further Personalizing Medicine in Immune Disorders: Genomic Findings and Hematopoietic Cell Transplantation Survival.
Morgan N Similuk, Sarah A Bannon, Jia Yan, Rajarshi Ghosh, Ekaterina E Damskey, Alexandra F Freeman

Transplantation· January 2026

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Obesity and hepatic steatosis in STAT3 hyper-IgE syndrome.
Meera Patel, Chen Wang, Amanda Urban, Iris Martin, Jean Ulrick, Alexandra F Freeman

J Allergy Clin Immunol Pract· November 2025

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IL12RB1 deficiency appearing in North America: expanding the clinical phenotypes.
Chen Wang, Beatriz E Marciano, Annalie J Harris, Alicia M Johnston, Evsen Apaydin Arikan, Alexandra F Freeman

Clin Infect Dis· November 2025

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STAT3-Dependent Regulation of CFTR and Ciliogenesis Is Essential for Mucociliary Clearance and Innate Airway Defense in Hyper-IgE Syndrome.
Ling Sun, Samantha A Walls, Hong Dang, Nancy L Quinney, Patrick R Sears, Alexandra F Freeman

Am J Respir Crit Care Med· October 2025

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TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function.
Qian Shen, Hao Wang, Jonathan A Roco, Xiangpeng Meng, Marita Bosticardo, Alexandra F Freeman

Nature· October 2025

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Publisher Correction: TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function.
Qian Shen, Hao Wang, Jonathan A Roco, Xiangpeng Meng, Marita Bosticardo, Alexandra F Freeman

Nature· October 2025

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Disseminated Histoplasmosis in Very Early Diagnosed De Novo STAT3-HIES.
Armen Sanosyan, Ran Hazan, Alexandra F Freeman, Erica G Schmitt, Caroline C Horner

J Clin Immunol· October 2025

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Immunopathological and microbial signatures of inflammatory bowel disease in partial RAG deficiency.
Riccardo Castagnoli, Francesca Pala, Poorani Subramanian, Cihan Oguz, Benjamin Schwarz, Alexandra F Freeman

J Exp Med· August 2025

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Allogeneic hematopoietic stem cell transplantation for STAT3 hyper-IgE syndrome: a worldwide study.
Christo Tsilifis, Johannes Raedler, Joanna Renke, Michael Medinger, Alexandra Laberko, Alexandra F Freeman

Blood Adv· August 2025

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Restoration of the human skin microbiome following immune recovery after hematopoietic stem cell transplantation.
You Che, Jungmin Han, Catriona P Harkins, Peng Hou, Sean Conlan, Alexandra F Freeman

Cell Host Microbe· August 2025

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Back With Vengeance: Delayed Gastrointestinal Sequelae of Histoplasmosis in a Patient With STAT3 Hyper-IgE Syndrome.
Disha Sharma, Alla Turshudzhyan, Amanda Urban, David E Kleiner, Theo Heller, Alexandra F Freeman

ACG Case Rep J· July 2025

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Allergic Fungal Rhinosinusitis Diagnosis, Management, Associated Conditions, Pathophysiology, and Future Directions: Summary of a Multidisciplinary Workshop.
Lauren T Roland, Cecelia Damask, Amber U Luong, Antoine Azar, Charles S Ebert, Alexandra F Freeman

Int Forum Allergy Rhinol· June 2025

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Skin imaging mass spectrometry of controls versus atopic dermatitis patients with and without mutations.
Jacquelyn Spathies, Grace Ratley, Brandon N D'Souza, Ashleigh A Sun, Portia Gough, Alexandra F Freeman

iScience· June 2025

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Interferon-γ therapy in patients with refractory disseminated coccidioidomycosis.
Chen Wang, Brenna A LaBere, Michell M Lozano Chinga, Annalie J Harris, Lindsey B Rosen, Alexandra F Freeman

Clin Infect Dis· May 2025

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Infection-Associated Immune Reconstitution Inflammatory Syndrome in Hematopoietic Cell Transplantation.
Mansi Chaturvedi, Brian P Epling, Luxin Pei, Brigit Sullivan, Hye Sun Kuehn, Alexandra F Freeman

Transpl Infect Dis· April 2025

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Clinical significance and antifungal susceptibility profile of 103 clinical isolates of species complex and obtained from NIH patients.
Mary M Czech, Jennifer Cuellar-Rodriguez, Kyung J Kwon-Chung, Frida Stock, Chioma I Aneke, Alexandra F Freeman

J Clin Microbiol· April 2025

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JAK-STAT signaling pathway, immunodeficiency, inflammation, immune dysregulation, and inborn errors of immunity.
Simran Samra, Jenna R E Bergerson, Alexandra F Freeman, Stuart E Turvey

J Allergy Clin Immunol· February 2025

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Hematopoietic cell transplantation for DOCK8 deficiency: Results from a prospective clinical trial.
Alexandra F Freeman, Corina E Gonzalez, Bonnie Yates, Kristen Cole, Lauren Little

J Allergy Clin Immunol· January 2025

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Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature.
Marita Bosticardo, Kerry Dobbs, Ottavia M Delmonte, Andrew J Martins, Francesca Pala, Alexandra F Freeman

Sci Immunol· January 2025

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STAT1 and STAT3 gain of function: clinically heterogenous immune regulatory disorders.
Peter Olbrich, Alexandra F Freeman

Curr Opin Allergy Clin Immunol· December 2024

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Altered Purinergic Signaling and CD8+ T Cell Dysregulation in STAT3 GOF Syndrome.
Jose S Campos Duran, Samir Sayed, Megan C Dalalo, Andrea A Mauracher, Montana S Knight, Alexandra F Freeman

bioRxiv· December 2024

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Safety but limited efficacy of donor lymphocyte infusion for post-transplantation cyclophosphamide-treated patients.
Krithika Shanmugasundaram, Scott Napier, Dimana Dimitrova, Anita Stokes, Jennifer Wilder, Alexandra F Freeman

Bone Marrow Transplant· November 2024

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Infections in Inborn Errors of STATs.
Chen Wang, Alexandra F Freeman

Pathogens· November 2024

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Germline mutations in a G protein identify signaling cross-talk in T cells.
Hyoungjun Ham, Huie Jing, Ian T Lamborn, Megan M Kober, Alexey Koval, Alexandra F Freeman

Science· September 2024

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Dysregulated Airway Host Defense in Hyper IgE Syndrome due to STAT3 Mutations.
Ling Sun, Samantha A Walls, Hong Dang, Nancy L Quinney, Patrick R Sears, Alexandra F Freeman

bioRxiv· August 2024

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