Publications by authors named "Alexandra Sevko"

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Immunomonitoring in bladder cancer: a short report on stability of leukocytes and proteins in refrigerated urine samples.
Alexandra Sevko, Claudia Prevosto, Suvetha Ragavan, Sonia Domingos-Pereira, Valérie Cesson

BMC Urol· December 2024

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Programmable cancer treatments: Engineering biology approaches for living cures.
Marc Biarnes Carrera, Alexandra Sevko, Nicholas Glanville, Livija Deban

Eng Biol· May 2024

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Enhancing Efficacy of TCR-engineered CD4 + T Cells Via Coexpression of CD8α.
Victoria E Anderson, Sara S Brilha, Anika M Weber, Annette Pachnio, Guy E Wiedermann, Alexandra Sevko

J Immunother· May 2023

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Tumor-Specific Regulatory T Cells from the Bone Marrow Orchestrate Antitumor Immunity in Breast Cancer.
Yingzi Ge, Hans-Henning Böhm, Anchana Rathinasamy, Maria Xydia, Xiaoying Hu, Alexandra Sevko

Cancer Immunol Res· December 2019

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The Linear ubiquitin chain assembly complex acts as a liver tumor suppressor and inhibits hepatocyte apoptosis and hepatitis.
Yutaka Shimizu, Nieves Peltzer, Alexandra Sevko, Elodie Lafont, Aida Sarr

Hepatology· June 2017

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Tadalafil has biologic activity in human melanoma. Results of a pilot trial with Tadalafil in patients with metastatic Melanoma (TaMe).
Jessica C Hassel, Huanhuan Jiang, Carolin Bender, Julia Winkler, Alexandra Sevko

Oncoimmunology· May 2017

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The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2.
Torsten Hartwig, Antonella Montinaro, Silvia von Karstedt, Alexandra Sevko, Silvia Surinova

Mol Cell· February 2017

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Myeloid Cells and Related Chronic Inflammatory Factors as Novel Predictive Markers in Melanoma Treatment with Ipilimumab.
Christoffer Gebhardt, Alexandra Sevko, Huanhuan Jiang, Ramtin Lichtenberger, Maike Reith

Clin Cancer Res· December 2015

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Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment.
Kirsten Ridder, Alexandra Sevko, Janina Heide, Maria Dams, Anne-Kathleen Rupp

Oncoimmunology· June 2015

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Myeloid-derived suppressor cells in malignant melanoma.
Viktor Umansky, Alexandra Sevko, Christoffer Gebhardt, Jochen Utikal

J Dtsch Dermatol Ges· November 2014

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Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals.
Laura Gatti, Alexandra Sevko, Michelandrea De Cesare, Noemi Arrighetti, Giacomo Manenti

Oncotarget· June 2014

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Tumor microenvironment and myeloid-derived suppressor cells.
Viktor Umansky, Alexandra Sevko

Cancer Microenviron· August 2013

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Ret transgenic mouse model of spontaneous skin melanoma: focus on regulatory T cells.
Viktor Umansky, Alexandra Sevko

Pigment Cell Melanoma Res· July 2013

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Cyclophosphamide promotes chronic inflammation-dependent immunosuppression and prevents antitumor response in melanoma.
Alexandra Sevko, Moshe Sade-Feldman, Julia Kanterman, Tillmann Michels, Christine S Falk

J Invest Dermatol· June 2013

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Antitumor effect of paclitaxel is mediated by inhibition of myeloid-derived suppressor cells and chronic inflammation in the spontaneous melanoma model.
Alexandra Sevko, Tillmann Michels, Melissa Vrohlings, Ludmila Umansky, Philipp Beckhove

J Immunol· March 2013

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Myeloid-derived suppressor cells interact with tumors in terms of myelopoiesis, tumorigenesis and immunosuppression: thick as thieves.
Alexandra Sevko, Viktor Umansky

J Cancer· February 2013

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Paclitaxel promotes differentiation of myeloid-derived suppressor cells into dendritic cells in vitro in a TLR4-independent manner.
Tillmann Michels, Galina V Shurin, Hiam Naiditch, Alexandra Sevko, Viktor Umansky

J Immunotoxicol· December 2012

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Application of paclitaxel in low non-cytotoxic doses supports vaccination with melanoma antigens in normal mice.
Alexandra Sevko, Veronika Kremer, Christine Falk, Ludmila Umansky, Michael R Shurin

J Immunotoxicol· December 2012

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Melanoma-induced immunosuppression and its neutralization.
Viktor Umansky, Alexandra Sevko

Semin Cancer Biol· August 2012

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Overcoming immunosuppression in the melanoma microenvironment induced by chronic inflammation.
Viktor Umansky, Alexandra Sevko

Cancer Immunol Immunother· February 2012

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Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model.
Christiane Meyer, Alexandra Sevko, Marcel Ramacher, Alexandr V Bazhin, Christine S Falk

Proc Natl Acad Sci U S A· October 2011

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Skin melanoma development in ret transgenic mice despite the depletion of CD25+Foxp3+ regulatory T cells in lymphoid organs.
Silvia Kimpfler, Alexandra Sevko, Sabine Ring, Christine Falk, Wolfram Osen

J Immunol· November 2009

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Differences in dendritic cell activation and distribution after intravenous, intraperitoneal, and subcutaneous injection of lymphoma cells in mice.
Alexandra L Sevko, Nadzeya Barysik, Lori Perez, Michael R Shurin, Valentin Gerein

Adv Exp Med Biol· October 2007

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