Publications by authors named "Alexandra Smink"

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Bifidobacterium animalis subsp. Lactis BL-99 Improves Maternal and Fetal Immune Responses and Pregnancy Outcomes in Pregnant Antibiotics-Treated Mice.
Marijke M Faas, Lieske Wekema, Carolien A van Loo-Bouwman, Gisela A Weiss, Wei-Lian Hung, Alexandra M Smink

Mol Nutr Food Res· November 2025

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Modulating adipose-derived stromal cells' secretomes by culture conditions: effects on angiogenesis, collagen deposition, and immunomodulation.
Erika Pinheiro-Machado, Claudia C Koster, Alexandra M Smink

Biosci Rep· May 2025

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ESM-1 and GBP-1 are associated with endothelial dysfunction: emerging biomarkers or key players in the pathophysiology of preeclampsia?
Ines Pronk, Joost H N Schuitemaker, Marijke M Faas, Alexandra M Smink

J Physiol· March 2025

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Shaping immunity: the influence of the maternal gut bacteria on fetal immune development.
Marijke M Faas, Alexandra M Smink

Semin Immunopathol· February 2025

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Secretome Analysis of Human and Rat Pancreatic Islets Co-Cultured with Adipose-Derived Stromal Cells Reveals a Signature with Enhanced Regenerative Capacities.
Erika Pinheiro-Machado, Bart J de Haan, Marten A Engelse, Alexandra M Smink

Cells· February 2025

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Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization.
Brenden N Moeun, Florent Lemaire, Alexandra M Smink, Hamid Ebrahimi Orimi, Richard L Leask

J Tissue Eng· January 2025

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The role of extracellular matrix hydrogels and adipose-derived stromal cells in soft tissue vascularization - A systematic review.
Vasilena E Getova, Erika Pinheiro-Machado, Martin C Harmsen, Janette K Burgess, Alexandra M Smink

Biomater Adv· November 2024

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Microfluidic Generation of Thin-Shelled Polyethylene Glycol-Tyramine Microgels for Non-Invasive Delivery of Immunoprotected β-Cells.
Nuno Araújo-Gomes, Barbara Zoetebier-Liszka, Bas van Loo, Malin Becker, Suzanne Nijhuis, Alexandra M Smink

Adv Healthc Mater· October 2024

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Culturing Conditions Dictate the Composition and Pathways Enrichment of Human and Rat Perirenal Adipose-Derived Stromal Cells' Secretomes.
Erika Pinheiro-Machado, Marijke M Faas, Bart J de Haan, Cyril Moers, Alexandra M Smink

Stem Cell Rev Rep· October 2024

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Necrostatin-1 releasing nanoparticles: In vitro and in vivo efficacy for supporting immunoisolated islet transplantation outcomes.
Alexandra M Smink, Juan D Medina, Bart J de Haan, Andrés J García, Paul de Vos

J Biomed Mater Res A· February 2024

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Towards standardization of human adipose-derived stromal cells secretomes.
Erika Pinheiro-Machado, Vasilena E Getova, Martin C Harmsen, Janette K Burgess, Alexandra M Smink

Stem Cell Rev Rep· October 2023

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Enhancing longevity of immunoisolated pancreatic islet grafts by modifying both the intracapsular and extracapsular environment.
Tian Qin, Alexandra M Smink, Paul de Vos

Acta Biomater· September 2023

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Extracellular matrix inclusion in immunoisolating alginate-based microcapsules promotes longevity, reduces fibrosis, and supports function of islet allografts in vivo.
Rei Kuwabara, Tian Qin, L Alberto Llacua, Shuxian Hu, Mark V Boekschoten, Alexandra M Smink

Acta Biomater· March 2023

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Mechanisms of Foreign Body Giant Cell Formation in Response to Implantable Biomaterials.
Farshid Eslami-Kaliji, Niloufar Hedayat Nia, Jonathan R T Lakey, Alexandra M Smink, Mohammadreza Mohammadi

Polymers (Basel)· March 2023

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Successful Islet Transplantation Into a Subcutaneous Polycaprolactone Scaffold in Mice and Pigs.
Alexandra M Smink, Samuel Rodriquez, Shiri Li, Bryan Ceballos, Nicole Corrales

Transplant Direct· January 2023

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Species-dependent impact of immunosuppressive squalene-gusperimus nanoparticles and adipose-derived stem cells on isolated human and rat pancreatic islets.
Carlos E Navarro Chica, Tian Qin, Erika Pinheiro-Machado, Bart J de Haan, M M Faas, Alexandra M Smink

Islets· December 2022

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Inclusion of extracellular matrix molecules and necrostatin-1 in the intracapsular environment of alginate-based microcapsules synergistically protects pancreatic β cells against cytokine-induced inflammatory stress.
Tian Qin, Shuxian Hu, Alexandra M Smink, Bart J de Haan, Luis A Silva-Lagos

Acta Biomater· July 2022

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Applying Immunomodulation to Promote Longevity of Immunoisolated Pancreatic Islet Grafts.
Rei Kuwabara, Shuxian Hu, Alexandra M Smink, Gorka Orive, Jonathan R T Lakey

Tissue Eng Part B Rev· February 2022

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determination of the immunosuppressive effect, internalization, and release mechanism of squalene-gusperimus nanoparticles for managing inflammatory responses.
Carlos E Navarro Chica, Tian Qin, Bart J de Haan, M M Faas, Alexandra M Smink

Artif Cells Nanomed Biotechnol· December 2021

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Tethering Cells via Enzymatic Oxidative Crosslinking Enables Mechanotransduction in Non-Cell-Adhesive Materials.
Tom Kamperman, Sieger Henke, João F Crispim, Niels G A Willemen, Pieter J Dijkstra, Alexandra M Smink

Adv Mater· October 2021

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DAMPening COVID-19 Severity by Attenuating Danger Signals.
Luis A Silva-Lagos, Janesh Pillay, Matijs van Meurs, Alexandra Smink, Peter H J van der Voort

Front Immunol· September 2021

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vascularization and islet function in a microwell device for pancreatic islet transplantation.
Alexandra M Smink, Katarzyna Skrzypek, Jolanda A L Liefers-Visser, Rei Kuwabara, Bart J de Haan

Biomed Mater· April 2021

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Toll-like receptor 2-modulating pectin-polymers in alginate-based microcapsules attenuate immune responses and support islet-xenograft survival.
Shuxian Hu, Rei Kuwabara, Carlos E Navarro Chica, Alexandra M Smink, Taco Koster

Biomaterials· January 2021

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Low methyl-esterified pectin protects pancreatic β-cells against diabetes-induced oxidative and inflammatory stress via galectin-3.
Shuxian Hu, Rei Kuwabara, Martin Beukema, Michela Ferrari, Bart J de Haan, Alexandra M Smink

Carbohydr Polym· December 2020

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Design and characterization of Squalene-Gusperimus nanoparticles for modulation of innate immunity.
Carlos E Navarro Chica, Bart J de Haan, M M Faas, Alexandra M Smink, Ligia Sierra

Int J Pharm· November 2020

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