Publications by authors named "Alexandra Tolia"

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Functional and topological analysis of PSENEN, the fourth subunit of the γ-secretase complex.
Lutgarde Serneels, Leen Bammens, An Zwijsen, Alexandra Tolia, Lucía Chávez-Gutiérrez

J Biol Chem· January 2024

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Withdrawal: Functional and topological analysis of Pen-2, the fourth subunit of the γ-secretase complex.
Leen Bammens, Lucía Chávez-Gutiérrez, Alexandra Tolia, An Zwijsen, Bart De Strooper

J Biol Chem· July 2023

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Structure of a Ca(2+)/CaM:Kv7.4 (KCNQ4) B-helix complex provides insight into M current modulation.
Qiang Xu, Aram Chang, Alexandra Tolia, Daniel L Minor

J Mol Biol· January 2013

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Calmodulin overexpression does not alter Cav1.2 function or oligomerization state.
Felix Findeisen, Alexandra Tolia, Ryan Arant, Eun Young Kim, Ehud Isacoff

Channels (Austin)· January 2012

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Chemical informatics and target identification in a zebrafish phenotypic screen.
Christian Laggner, David Kokel, Vincent Setola, Alexandra Tolia, Henry Lin

Nat Chem Biol· December 2011

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Mutagenesis mapping of the presenilin 1 calcium leak conductance pore.
Omar Nelson, Charlene Supnet, Alexandra Tolia, Katrien Horré, Bart De Strooper

J Biol Chem· June 2011

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Functional and topological analysis of Pen-2, the fourth subunit of the gamma-secretase complex.
Leen Bammens, Lucía Chávez-Gutiérrez, Alexandra Tolia, An Zwijsen, Bart De Strooper

J Biol Chem· April 2011

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Structure and function of gamma-secretase.
Alexandra Tolia, Bart De Strooper

Semin Cell Dev Biol· April 2009

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Transmembrane domain 9 of presenilin determines the dynamic conformation of the catalytic site of gamma-secretase.
Alexandra Tolia, Katrien Horré, Bart De Strooper

J Biol Chem· July 2008

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Glu(332) in the Nicastrin ectodomain is essential for gamma-secretase complex maturation but not for its activity.
Lucía Chávez-Gutiérrez, Alexandra Tolia, Elke Maes, Tong Li, Philip C Wong

J Biol Chem· July 2008

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Contribution of presenilin transmembrane domains 6 and 7 to a water-containing cavity in the gamma-secretase complex.
Alexandra Tolia, Lucía Chávez-Gutiérrez, Bart De Strooper

J Biol Chem· September 2006

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Presenilin-1 maintains a nine-transmembrane topology throughout the secretory pathway.
Dragana Spasic, Alexandra Tolia, Katleen Dillen, Veerle Baert, Bart De Strooper

J Biol Chem· September 2006

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Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes.
Sébastien S Hébert, Lutgarde Serneels, Alexandra Tolia, Katleen Craessaerts, Carmen Derks

EMBO Rep· July 2006

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Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms.
Mostafa Bentahir, Omar Nyabi, Jan Verhamme, Alexandra Tolia, Katrien Horré

J Neurochem· February 2006

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