Publications by authors named "Alexandra Walls"

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Computationally designed mRNA-launched protein nanoparticle immunogens elicit protective antibody and T cell responses in mice.
Grace G Hendricks, Lilit Grigoryan, Mary Jane Navarro, Nicholas J Catanzaro, Miranda L Hubbard, Alexandra C Walls

Sci Transl Med· October 2025

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Phylogeny-driven design of broadly protective sarbecovirus receptor-binding domain nanoparticle vaccines.
Amin Addetia, Alexandra Schäfer, Kaitlin Sprouse, Adian Valdez, Ashley Taylor, Alexandra C Walls

bioRxiv· May 2025

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Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV.
Cara W Chao, Kaitlin R Sprouse, Marcos C Miranda, Nicholas J Catanzaro, Miranda L Hubbard, Alexandra C Walls

Cell Rep· December 2024

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Potent neutralization of SARS-CoV-2 variants by RBD nanoparticle and prefusion-stabilized spike immunogens.
Marcos C Miranda, Elizabeth Kepl, Mary Jane Navarro, Chengbo Chen, Max Johnson, Alexandra C Walls

NPJ Vaccines· October 2024

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An Investigation of Parturient Ocular Appearance in Sows.
Alexandra Walls, Evelyn Hall, Sabrina Lomax, Roslyn Bathgate

Animals (Basel)· September 2024

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Computationally designed mRNA-launched protein nanoparticle vaccines.
Grace G Hendricks, Lilit Grigoryan, Mary Jane Navarro, Nicholas J Catanzaro, Miranda L Hubbard, Alexandra C Walls

bioRxiv· July 2024

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A multivalent mRNA monkeypox virus vaccine (BNT166) protects mice and macaques from orthopoxvirus disease.
Adam Zuiani, Charles L Dulberger, Nilushi S De Silva, Meghan Marquette, Yu-Jung Lu, Alexandra C Walls

Cell· March 2024

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Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV.
Cara W Chao, Kaitlin R Sprouse, Marcos C Miranda, Nicholas J Catanzaro, Miranda L Hubbard, Alexandra C Walls

bioRxiv· March 2024

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Structural changes in the SARS-CoV-2 spike E406W mutant escaping a clinical monoclonal antibody cocktail.
Amin Addetia, Young-Jun Park, Tyler Starr, Allison J Greaney, Kaitlin R Sprouse, Alexandra C Walls

Cell Rep· June 2023

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Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape.
Roberta Marzi, Jessica Bassi, Chiara Silacci-Fregni, Istvan Bartha, Francesco Muoio, Alexandra C Walls

iScience· January 2023

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SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines.
John E Bowen, Young-Jun Park, Cameron Stewart, Jack T Brown, William K Sharkey, Alexandra C Walls

Sci Immunol· December 2022

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Close relatives of MERS-CoV in bats use ACE2 as their functional receptors.
Qing Xiong, Lei Cao, Chengbao Ma, M Alejandra Tortorici, Chen Liu, Alexandra C Walls

Nature· December 2022

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Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Young-Jun Park, Dora Pinto, Alexandra C Walls, Zhuoming Liu, Anna De Marco

Science· November 2022

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Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains.
Tyler N Starr, Allison J Greaney, Cameron M Stewart, Alexandra C Walls, William W Hannon

PLoS Pathog· November 2022

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Antigen- and scaffold-specific antibody responses to protein nanoparticle immunogens.
John C Kraft, Minh N Pham, Laila Shehata, Mitch Brinkkemper, Seyhan Boyoglu-Barnum, Alexandra C Walls

Cell Rep Med· October 2022

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Defining "Normal" in Pig Parturition.
Alexandra Walls, Bianca Hatze, Sabrina Lomax, Roslyn Bathgate

Animals (Basel)· October 2022

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Safety and immunogenicity of a SARS-CoV-2 recombinant protein nanoparticle vaccine (GBP510) adjuvanted with AS03: A randomised, placebo-controlled, observer-blinded phase 1/2 trial.
Joon Young Song, Won Suk Choi, Jung Yeon Heo, Jin Soo Lee, Dong Sik Jung, Alexandra C Walls

EClinicalMedicine· September 2022

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Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape.
Roberta Marzi, Jessica Bassi, Chiara Silacci-Fregni, Istvan Bartha, Francesco Muoio, Alexandra C Walls

bioRxiv· September 2022

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Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Young-Jun Park, Dora Pinto, Alexandra C Walls, Zhuoming Liu, Anna De Marco

bioRxiv· August 2022

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Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines.
John E Bowen, Amin Addetia, Ha V Dang, Cameron Stewart, Jack T Brown, Alexandra C Walls

Science· August 2022

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ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Jun Siong Low, Josipa Jerak, M Alejandra Tortorici, Matthew McCallum, Dora Pinto, Alexandra C Walls

Science· August 2022

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Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.
Dami A Collier, Anna De Marco, Isabella A T M Ferreira, Bo Meng, Rawlings P Datir, Alexandra C Walls

Nature· August 2022

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Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine.
Prabhu S Arunachalam, Yupeng Feng, Usama Ashraf, Mengyun Hu, Alexandra C Walls

Sci Transl Med· August 2022

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Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice.
Alexandra C Walls, Laura A VanBlargan, Kai Wu, Angela Choi, Mary Jane Navarro

Cell Rep· August 2022

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Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein.
M Alejandra Tortorici, Alexandra C Walls, Anshu Joshi, Young-Jun Park, Rachel T Eguia

Cell· June 2022

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