Publications by authors named "Alexandra Winkeler"

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Synthesis, Labeling, and Biological Evaluation of P2Y Receptor Radioligands for Positron Emission Tomography Imaging of Neuroinflammation.
Eugénie Pincemail, Marie-Anne Peyronneau, Caroline Denis, Hayet Bensalah, Margot Corbel, Alexandra Winkeler

ACS Chem Neurosci· July 2025

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Selective, Non-nucleotidic Radiotracer for P2Y Receptors: Design, Synthesis, Characterization, and Imaging of Brain Slices.
Haneen Al-Hroub, Hashem Ali M Al Musawi, Aliaa Abdelrahman, Vigneshwaran Namasivayam, Margot Corbel, Alexandra Winkeler

J Med Chem· June 2025

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Decreased opioid receptor availability and impaired neurometabolic coupling as signatures of morphine tolerance in male rats: A positron emission tomography study.
Amélie Soyer, Sarah Leterrier, Sébastien Goutal, Cassandre Corvo, Wadad Saba, Alexandra Winkeler

Biomed Pharmacother· February 2025

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PET imaging of neuroinflammation: any credible alternatives to TSPO yet?
Fabien Chauveau, Alexandra Winkeler, Sylvie Chalon, Hervé Boutin, Guillaume Becker

Mol Psychiatry· January 2025

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Impaired brain glucose metabolism as a biomarker for evaluation of dodecyl creatine ester in creatine transporter deficiency: Insights from patient brain-derived organoids and in vivo [18F]FDG PET imaging in a mouse model.
Clémence Disdier, Amélie Soyer, Léa Broca-Brisson, Sébastien Goutal, Anne-Cécile Guyot, Alexandra Winkeler

Neurobiol Dis· November 2024

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[F]2-fluoro-2-deoxy-sorbitol ([F]FDS) PET imaging repurposed for quantitative estimation of blood-brain barrier permeability in a rat model of Alzheimer's disease.
Amélie Soyer, Sébastien Goutal, Sarah Leterrier, Solène Marie, Benoit Larrat, Alexandra Winkeler

Ann Pharm Fr· September 2024

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Imaging quantitative changes in blood-brain barrier permeability using [F]2-fluoro-2-deoxy-sorbitol ([F]FDS) PET in relation to glial cell recruitment in a mouse model of endotoxemia.
Sarah Leterrier, Sébastien Goutal, Gaëlle Hugon, Maud Goislard, Wadad Saba, Alexandra Winkeler

J Cereb Blood Flow Metab· July 2024

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TSPO PET Imaging as a Potent Non-Invasive Biomarker for Diffuse Intrinsic Pontine Glioma in a Patient-Derived Orthotopic Rat Model.
Céline Chevaleyre, Dimitri Kereselidze, Fabien Caillé, Nicolas Tournier, Nagore G Olaciregui, Alexandra Winkeler

Int J Mol Sci· October 2022

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Interrogating Glioma-Associated Microglia and Macrophage Dynamics Under CSF-1R Therapy with Multitracer In Vivo PET/MRI.
Claudia Foray, Cristina Barca, Alexandra Winkeler, Stefan Wagner, Sven Hermann

J Nucl Med· September 2022

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In Vivo Quantitative Imaging of Glioma Heterogeneity Employing Positron Emission Tomography.
Cristina Barca, Claudia Foray, Bastian Zinnhardt, Alexandra Winkeler, Ulrich Herrlinger

Cancers (Basel)· June 2022

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Impact of Donepezil on Brain Glucose Metabolism Assessed Using [F]2-Fluoro-2-deoxy-D-Glucose Positron Emission Tomography Imaging in a Mouse Model of Alzheimer's Disease Induced by Intracerebroventricular Injection of Amyloid-Beta Peptide.
Gaëlle Hugon, Sébastien Goutal, Marie Sarazin, Michel Bottlaender, Fabien Caillé, Alexandra Winkeler

Front Neurosci· February 2022

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Imaging of the glioma microenvironment by TSPO PET.
Bastian Zinnhardt, Federico Roncaroli, Claudia Foray, Erjon Agushi, Bahiya Osrah, Alexandra Winkeler

Eur J Nucl Med Mol Imaging· December 2021

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[F]2-Fluoro-2-deoxy-sorbitol PET Imaging for Quantitative Monitoring of Enhanced Blood-Brain Barrier Permeability Induced by Focused Ultrasound.
Gaëlle Hugon, Sébastien Goutal, Ambre Dauba, Louise Breuil, Benoit Larrat, Alexandra Winkeler

Pharmaceutics· October 2021

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Imaging temozolomide-induced changes in the myeloid glioma microenvironment.
Claudia Foray, Silvia Valtorta, Cristina Barca, Alexandra Winkeler, Wolfgang Roll

Theranostics· August 2021

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Impact of blood-brain barrier permeabilization induced by ultrasound associated to microbubbles on the brain delivery and kinetics of cetuximab: An immunoPET study using Zr-cetuximab.
Vu Long Tran, Anthony Novell, Nicolas Tournier, Matthieu Gerstenmayer, Arnaud Schweitzer-Chaput, Alexandra Winkeler

J Control Release· December 2020

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TSPO imaging-guided characterization of the immunosuppressive myeloid tumor microenvironment in patients with malignant glioma.
Bastian Zinnhardt, Michael Müther, Wolfgang Roll, Philipp Backhaus, Astrid Jeibmann, Alexandra Winkeler

Neuro Oncol· July 2020

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Multimodal Molecular Imaging of the Tumour Microenvironment.
Claudia Foray, Cristina Barca, Philipp Backhaus, Sonja Schelhaas, Alexandra Winkeler

Adv Exp Med Biol· February 2020

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Correction to: Multimodal Molecular Imaging of the Tumour Microenvironment.
Claudia Foray, Cristina Barca, Philipp Backhaus, Sonja Schelhaas, Alexandra Winkeler

Adv Exp Med Biol· January 2020

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Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.
Alessandro Villa, Barbara Klein, Bieneke Janssen, Jordi Pedragosa, Giovanna Pepe, Alexandra Winkeler

Theranostics· September 2019

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TSPO-PET and diffusion-weighted MRI for imaging a mouse model of infiltrative human glioma.
Hayet Pigeon, Elodie A Pérès, Charles Truillet, Benoit Jego, Fawzi Boumezbeur, Alexandra Winkeler

Neuro Oncol· June 2019

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From Structure-Activity Relationships on Thiazole Derivatives to the In Vivo Evaluation of a New Radiotracer for Cannabinoid Subtype 2 PET Imaging.
Fabien Caillé, Fanny Cacheux, Marie-Anne Peyronneau, Benoît Jego, Emilie Jaumain, Alexandra Winkeler

Mol Pharm· November 2017

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Combined PET Imaging of the Inflammatory Tumor Microenvironment Identifies Margins of Unique Radiotracer Uptake.
Bastian Zinnhardt, Hayet Pigeon, Benoit Thézé, Thomas Viel, Lydia Wachsmuth, Alexandra Winkeler

Cancer Res· April 2017

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PET imaging of cannabinoid type 2 receptors with [C]A-836339 did not evidence changes following neuroinflammation in rats.
Geraldine Pottier, Vanessa Gómez-Vallejo, Daniel Padro, Raphaël Boisgard, Frédéric Dollé, Alexandra Winkeler

J Cereb Blood Flow Metab· March 2017

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Evaluation of PET Imaging Performance of the TSPO Radioligand [18F]DPA-714 in Mouse and Rat Models of Cancer and Inflammation.
Jinzi Zheng, Alexandra Winkeler, Marie-Anne Peyronneau, Frédéric Dollé, Raphaël Boisgard

Mol Imaging Biol· February 2016

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The translocator protein radioligand 18F-DPA-714 monitors antitumor effect of erufosine in a rat 9L intracranial glioma model.
Ali R Awde, Raphaël Boisgard, Benoit Thézé, Albertine Dubois, Jinzi Zheng, Alexandra Winkeler

J Nucl Med· December 2013

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