Publications by authors named "Alexandre Alcais"

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Bedaquiline Activity against Leprosy.
Abdoulaye Fomba, Fadima C Haidara, Mamoudou Kodio, Catherine Arama, Emmanuelle Cambau

N Engl J Med· June 2025

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Insights into leprosy epidemiology from an isolated population located in the Brazilian Amazon.
Ciane Cristina de Oliveira Mackert, Fernando Panissa Lázaro, Márcia Olandowski, Helena Regina Salomé D'Espindula, Andressa Mayra Dos Santos

Sci Rep· February 2025

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Severe adult hemophagocytic lymphohistiocytosis (HLHa) correlates with HLH-related gene variants.
Coralie Bloch, Jean Philippe Jais, Marine Gil, Marouane Boubaya, Yves Lepelletier, Alexandre Alcais

J Allergy Clin Immunol· January 2024

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Allele-dependent interaction of LRRK2 and NOD2 in leprosy.
Monica Dallmann-Sauer, Yong Zhong Xu, Ana Lúcia França da Costa, Shao Tao, Tiago Araujo Gomes

PLoS Pathog· March 2023

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Taking population stratification into account by local permutations in rare-variant association studies on small samples.
Jimmy Mullaert, Matthieu Bouaziz, Yoann Seeleuthner, Benedetta Bigio, Jean-Laurent Casanova

Genet Epidemiol· December 2021

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Deep resequencing identifies candidate functional genes in leprosy GWAS loci.
Vinicius M Fava, Monica Dallmann-Sauer, Marianna Orlova, Wilian Correa-Macedo, Nguyen Van Thuc

PLoS Negl Trop Dis· December 2021

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Controlling for human population stratification in rare variant association studies.
Matthieu Bouaziz, Jimmy Mullaert, Benedetta Bigio, Yoann Seeleuthner, Jean-Laurent Casanova, Alexandre Alcais

Sci Rep· September 2021

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Genome-wide association study of resistance to Mycobacterium tuberculosis infection identifies a locus at 10q26.2 in three distinct populations.
Jocelyn Quistrebert, Marianna Orlova, Gaspard Kerner, Le Thi Ton, Nguyễn Trong Luong

PLoS Genet· March 2021

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Improving the diagnostic efficiency of primary immunodeficiencies with targeted next-generation sequencing.
Mathieu Fusaro, Jérémie Rosain, Virginie Grandin, Nathalie Lambert, Sylvain Hanein, Alexandre Alcais

J Allergy Clin Immunol· February 2021

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The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions.
Monica Dallmann-Sauer, Vinicius M Fava, Chaïma Gzara, Marianna Orlova, Nguyen Van Thuc

PLoS Pathog· August 2020

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Reply to Zhang et al.: The differential role of LRRK2 variants in nested leprosy phenotypes.
Vinicius M Fava, Aurélie Cobat, Chaïma Gzara, Alexandre Alcaïs, Laurent Abel

Proc Natl Acad Sci U S A· May 2020

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Family-based genome-wide association study of leprosy in Vietnam.
Chaima Gzara, Monica Dallmann-Sauer, Marianna Orlova, Nguyen Van Thuc, Vu Hong Thai

PLoS Pathog· May 2020

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Genome-wide association study of Buruli ulcer in rural Benin highlights role of two LncRNAs and the autophagy pathway.
Jeremy Manry, Quentin B Vincent, Christian Johnson, Maya Chrabieh, Lazaro Lorenzo

Commun Biol· April 2020

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Skin-specific antibodies neutralizing mycolactone toxin during the spontaneous healing of infection.
Mélanie Foulon, Amélie Pouchin, Jérémy Manry, Fida Khater, Marie Robbe-Saule

Sci Adv· February 2020

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French-style genetics v. 2.0: The "e-CohortE" project.
Henri-Corto Stoeklé, Marc Bollet, Aurélie Cobat, Philippe Charlier, Oudy Ch Bloch

Clin Genet· October 2019

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A 1-Year Prospective French Nationwide Study of Emergency Hospital Admissions in Children and Adults with Primary Immunodeficiency.
Hélène Coignard-Biehler, Nizar Mahlaoui, Benoit Pilmis, Vincent Barlogis, Pauline Brosselin, Alexandre Alcais

J Clin Immunol· October 2019

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Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson's disease.
Vinicius M Fava, Yong Zhong Xu, Guillaume Lettre, Nguyen Van Thuc, Marianna Orlova

Proc Natl Acad Sci U S A· July 2019

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Genetic diagnosis of primary immunodeficiencies: A survey of the French national registry.
Nizar Mahlaoui, Capucine Picard, Perrine Bach, Laurence Costes, Virginie Courteille

J Allergy Clin Immunol· April 2019

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Microdeletion on chromosome 8p23.1 in a familial form of severe Buruli ulcer.
Quentin B Vincent, Aziz Belkadi, Cindy Fayard, Estelle Marion, Ambroise Adeye

PLoS Negl Trop Dis· April 2018

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Prevalence of primary immunodeficiencies in France is underestimated.
Nizar Mahlaoui, Jean-Philippe Jais, Pauline Brosselin, Cecile Mignot, Beatrice Beaurain

J Allergy Clin Immunol· December 2017

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Autoimmune and inflammatory manifestations occur frequently in patients with primary immunodeficiencies.
Alain Fischer, Johan Provot, Jean-Philippe Jais, Alexandre Alcais, Nizar Mahlaoui

J Allergy Clin Immunol· November 2017

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An eQTL variant of ZXDC is associated with IFN-γ production following Mycobacterium tuberculosis antigen-specific stimulation.
Fabienne Jabot-Hanin, Aurélie Cobat, Jacqueline Feinberg, Marianna Orlova, Jonathan Niay

Sci Rep· October 2017

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A genome wide association study identifies a lncRna as risk factor for pathological inflammatory responses in leprosy.
Vinicius M Fava, Jeremy Manry, Aurélie Cobat, Marianna Orlova, Nguyen Van Thuc

PLoS Genet· February 2017

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Age-Dependent Association of / Variants and Leprosy Type 1 Reaction.
Vinicius M Fava, Carolinne Sales-Marques, Alexandre Alcaïs, Milton O Moraes, Erwin Schurr

Front Immunol· February 2017

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Whole-exome sequencing to analyze population structure, parental inbreeding, and familial linkage.
Aziz Belkadi, Vincent Pedergnana, Aurélie Cobat, Yuval Itan, Quentin B Vincent, Alexandre Alcais

Proc Natl Acad Sci U S A· June 2016

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