Publications by authors named "Alexandre Amaral"

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Nitrosative Stress Mediates Disruption of Redox Homeostasis and Oxidative Phosphorylation Caused by 3-Hydroxyisobutyric Acid in Cerebral Cortex of Developing Rats.
Rafael Teixeira Ribeiro, Rafael Palavro, Ângela Beatris Zeminiaçak, Ângela Zanatta, Ediandra Tissot Castro, Alexandre Umpierrez Amaral

Mol Neurobiol· December 2025

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Simvastatin markedly alters locomotor behavior parameters and induces mortality in planarians.
Juliana Feix, Camila Caetano Solek, Karina Mara Carus, Valentina de Aguiar Pedott, Luiz Carlos Cichota, Alexandre Umpierrez Amaral

Eur J Pharmacol· October 2025

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Intracerebral Administration of Hydrogen Sulfide Impairs Bioenergetics, Redox Status and Mitochondrial Quality Control in Rat Striatum.
Manuela Bianchin Marcuzzo, Josyane de Andrade Silveira, Camila Vieira Pinheiro, Jaqueline Santana da Rosa, Angela B Zemniaçak, Alexandre U Amaral

Neurotox Res· September 2025

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Disturbances in mitochondrial quality control and mitochondria-lysosome contact underlie the cerebral cortex and heart damage of mucopolysaccharidosis type II mice.
Camila Vieira Pinheiro, Rafael Teixeira Ribeiro, Ana Cristina Roginski, Morgana Brondani, Ângela Beatris Zemniaçak, Alexandre Umpierrez Amaral

Metab Brain Dis· April 2025

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Brazilian Thoracic Association recommendations for the management of lymphangioleiomyomatosis.
Bruno Guedes Baldi, Paulo Henrique Ramos Feitosa, Adalberto Sperb Rubin, Alexandre Franco Amaral, Carolina Salim Gonçalves Freitas

J Bras Pneumol· February 2025

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Disturbances in mitochondrial bioenergetics and control quality and unbalanced redox homeostasis in the liver of a mouse model of mucopolysaccharidosis type II.
Camila Vieira Pinheiro, Rafael Teixeira Ribeiro, Ana Cristina Roginski, Morgana Brondani, Ângela Beatris Zemniaçak, Alexandre Umpierrez Amaral

Mol Cell Biochem· January 2025

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Protective effects of the PPAR agonist bezafibrate against disruption of redox and energy homeostasis, neuronal death, astroglial reactivity, and neuroinflammation induced in vivo by D-2-hydroxyglutaric acid in rat brain.
Rafael Teixeira Ribeiro, Manuela Bianchin Marcuzzo, Andrey Vinícios Soares Carvalho, Rafael Palavro, Ediandra Tissot Castro, Alexandre Umpierrez Amaral

Eur J Pharmacol· January 2025

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α-Ketoisocaproic Acid Disrupts Mitochondrial Bioenergetics in the Brain of Neonate Rats: Molecular Modeling Studies of α-ketoglutarate Dehydrogenase Subunits Inhibition.
Ângela Beatris Zemniaçak, Rafael Teixeira Ribeiro, Gustavo Machado das Neves, Sâmela de Azevedo Cunha, Tailine Quevedo Tavares, Alexandre Umpierrez Amaral

Neurochem Res· January 2025

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Clinical and Functional Outcomes Associated with Quality of Life in Patients with Lymphangioleiomyomatosis: A Cross-Sectional Study.
Douglas Silva Queiroz, Cibele Cristine Berto Marques da Silva, Martina Rodrigues Oliveira, Alexandre Franco Amaral, Carlos Roberto Ribeiro Carvalho

Lung· December 2024

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Oxidative Stress Associated With Increased Reactive Nitrogen Species Generation in the Liver and Kidney Caused by a Major Metabolite Accumulating in Tyrosinemia Type 1.
Julia Gabrieli Bender, Rafael Teixeira Ribeiro, Ângela Beatris Zemniaçak, Rafael Palavro, Rafael Aguiar Marschner, Alexandre Umpierrez Amaral

Cell Biochem Funct· December 2024

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Impairment of neuromotor development and cognition associated with histopathological and neurochemical abnormalities in the cerebral cortex and striatum of glutaryl-CoA dehydrogenase deficient mice.
Ediandra Tissot Castro, Rafael Teixeira Ribeiro, Andrey Vinicios Soares Carvalho, Diorlon Nunes Machado, Ângela Beatris Zemniaçak, Alexandre Umpierrez Amaral

Neurochem Int· December 2024

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Drug-induced lung disease: a narrative review.
Guilherme das Posses Bridi, Eduardo Kaiser Ururahy Nunes Fonseca, Ronaldo Adib Kairalla, Alexandre Franco Amaral, Bruno Guedes Baldi

J Bras Pneumol· October 2024

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In Vivo Intracerebral Administration of α-Ketoisocaproic Acid to Neonate Rats Disrupts Brain Redox Homeostasis and Promotes Neuronal Death, Glial Reactivity, and Myelination Injury.
Ângela Beatris Zemniaçak, Rafael Teixeira Ribeiro, Camila Vieira Pinheiro, Sâmela de Azevedo Cunha, Tailine Quevedo Tavares, Alexandre Umpierrez Amaral

Mol Neurobiol· May 2024

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Clinical, tomographic and functional comparison of sporadic and tuberous sclerosis complex-associated forms of lymphangioleiomyomatosis: a retrospective cohort study.
Martina Rodrigues Oliveira, Mark Wanderley, Carolina Salim Gonçalves Freitas, Ronaldo Adib Kairalla, Rodrigo Caruso Chate, Alexandre Franco Amaral

ERJ Open Res· March 2024

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Disturbance of mitochondrial functions caused by N-acetylglutamate and N-acetylmethionine in brain of adolescent rats: Potential relevance in aminoacylase 1 deficiency.
Vanessa Trindade Bortoluzzi, Rafael Teixeira Ribeiro, Ângela Beatris Zemniaçak, Sâmela de Azevedo Cunha, Jörn Oliver Sass, Alexandre Umpierrez Amaral

Neurochem Int· December 2023

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N-Acetylglutamate and N-acetylmethionine compromise mitochondrial bioenergetics homeostasis and glutamate oxidation in brain of developing rats: Potential implications for the pathogenesis of ACY1 deficiency.
Vanessa Trindade Bortoluzzi, Rafael Teixeira Ribeiro, Camila Vieira Pinheiro, Ediandra Tissot Castro, Tailine Quevedo Tavares, Alexandre Umpierrez Amaral

Biochem Biophys Res Commun· December 2023

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Idiopathic pulmonary fibrosis: current diagnosis and treatment.
Alexandre Franco Amaral, Philippe de Figueiredo Braga Colares, Ronaldo Adib Kairalla

J Bras Pneumol· August 2023

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Disruption of mitochondrial bioenergetics, calcium retention capacity and cell viability caused by D-2-hydroxyglutaric acid in the heart.
Rafael Teixeira Ribeiro, Ana Cristina Roginski, Rafael Aguiar Marschner, Simone Magagnin Wajner, Roger Frigério Castilho, Alexandre Umpierrez Amaral

Biochimie· April 2023

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L-2-Hydroxyglutaric Acid Administration to Neonatal Rats Elicits Marked Neurochemical Alterations and Long-Term Neurobehavioral Disabilities Mediated by Oxidative Stress.
Rafael Teixeira Ribeiro, Andrey Vinícios Soares Carvalho, Rafael Palavro, Luz Elena Durán-Carabali, Ângela Beatris Zemniaçak, Alexandre Umpierrez Amaral

Neurotox Res· April 2023

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Disruption of mitochondrial bioenergetics and calcium homeostasis by phytanic acid in the heart: Potential relevance for the cardiomyopathy in Refsum disease.
Ângela Beatriz Zemniaçak, Ana Cristina Roginski, Rafael Teixeira Ribeiro, Julia Gabrieli Bender, Rafael Aguiar Marschner, Alexandre Umpierrez Amaral

Biochim Biophys Acta Bioenerg· April 2023

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Latin American Registry of Idiopathic Pulmonary Fibrosis (REFIPI): Clinical Characteristics, Evolution and Treatment.
Fabián Caro, Ivette Buendía-Roldán, Lorena Noriega-Aguirre, María L Alberti, Alexandre Amaral

Arch Bronconeumol· December 2022

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Disruption of mitochondrial functions involving mitochondrial permeability transition pore opening caused by maleic acid in rat kidney.
Ana Cristina Roginski, Ângela Beatris Zemniaçak, Rafael Aguiar Marschner, Simone Magagnin Wajner, Rafael Teixeira Ribeiro, Alexandre Umpierrez Amaral

J Bioenerg Biomembr· August 2022

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Pathophysiology of maple syrup urine disease: Focus on the neurotoxic role of the accumulated branched-chain amino acids and branched-chain α-keto acids.
Alexandre Umpierrez Amaral, Moacir Wajner

Neurochem Int· July 2022

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Something not so new for lymphangioleiomyomatosis: is VEGF-D a glass half empty or half full?
Alexandre Franco Amaral, Carlos Roberto Ribeiro Carvalho, Bruno Guedes Baldi

J Bras Pneumol· March 2022

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Microbiological assessment at slaughter of chicken carcasses from commercial, backyard and semi-backyard production systems.
Débora Tamanaha Garcia, Yago Fernandes Nascimento, Sthefany da Cunha Dias, Amanda Oliveira Moura, Priscila Cristina Costa, Alexandre Bicalho do Amaral

J Infect Dev Ctries· December 2021

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