Publications by authors named "Alexandre Avrameas"

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B cell depletion and BAFF receptor blockade with ianalumab (VAY736) for the treatment of moderate-to-severe systemic lupus erythematosus: a phase 2 randomised, double-blind, placebo-controlled trial with subsequent open-label treatment.
Nancy Agmon-Levin, Stanislav Ignatenko, Alexander Gordienko, Josefina Cortés-Hernández, Pongthorn Narongroeknawin, Alexandre Avrameas

Ann Rheum Dis· December 2025

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Safety and Efficacy of Ianalumab in Patients With Sjögren's Disease: 52-Week Results From a Randomized, Placebo-Controlled, Phase 2b Dose-Ranging Study.
Thomas Dörner, Simon J Bowman, Robert Fox, Xavier Mariette, Athena Papas, Alexandre Avrameas

Arthritis Rheumatol· May 2025

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Efficacy and safety of remibrutinib, a selective potent oral BTK inhibitor, in Sjögren's syndrome: results from a randomised, double-blind, placebo-controlled phase 2 trial.
Thomas Dörner, Martin Kaul, Antónia Szántó, Jui-Cheng Tseng, Athena S Papas, Alexandre Avrameas

Ann Rheum Dis· February 2024

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First-in-Human Study of the Safety, Pharmacokinetics, and Pharmacodynamics of MHV370, a Dual Inhibitor of Toll-Like Receptors 7 and 8, in Healthy Adults.
Tamas Shisha, Maximilian G Posch, Jeanette Lehmann, Roland Feifel, Tobias Junt, Alexandre Avrameas

Eur J Drug Metab Pharmacokinet· September 2023

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Central and Peripheral Inflammation in Mild Cognitive Impairment in the Context of Alzheimer's Disease.
Inès Schmidt-Morgenroth, Philippe Michaud, Fabrizio Gasparini, Alexandre Avrameas

Int J Mol Sci· June 2023

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Disease Association of Anti‒Carboxyethyl Lysine Autoantibodies in Hidradenitis Suppurativa.
Giulio Macchiarella, Vanessa Cornacchione, Celine Cojean, Julia Riker, Yichen Wang, Alexandre Avrameas

J Invest Dermatol· February 2023

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Lipidomics Profiling of Hidradenitis Suppurativa Skin Lesions Reveals Lipoxygenase Pathway Dysregulation and Accumulation of Proinflammatory Leukotriene B4.
Carlos A Penno, Petra Jäger, Claire Laguerre, Franziska Hasler, Andreas Hofmann, Alexandre Avrameas

J Invest Dermatol· December 2020

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Assessment of the anti-CD40 antibody iscalimab in patients with primary Sjögren's syndrome: a multicentre, randomised, double-blind, placebo-controlled, proof-of-concept study.
Benjamin A Fisher, Antonia Szanto, Wan-Fai Ng, Michele Bombardieri, Maximilian G Posch, Alexandre Avrameas

Lancet Rheumatol· March 2020

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First-in-human clinical trial to assess pharmacokinetics, pharmacodynamics, safety, and tolerability of iscalimab, an anti-CD40 monoclonal antibody.
Pascal Espié, YanLing He, Phillip Koo, Denise Sickert, Cyrielle Dupuy, Alexandre Avrameas

Am J Transplant· February 2020

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The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease.
Ulf Neumann, Mike Ufer, Laura H Jacobson, Marie-Laure Rouzade-Dominguez, Gunilla Huledal, Alexandre Avrameas

EMBO Mol Med· November 2018

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Development and validation of an ELISA at acidic pH for the quantitative determination of IL-13 in human plasma and serum.
Julie Doucet, An Zhao, Jean Fu, Alexandre Avrameas

Dis Markers· June 2014

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Validation of immunoassay for protein biomarkers: bioanalytical study plan implementation to support pre-clinical and clinical studies.
Marie-Anne Valentin, Shenglin Ma, An Zhao, François Legay, Alexandre Avrameas

J Pharm Biomed Anal· July 2011

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A novel method for quantitative measurement of a therapeutic monoclonal antibody in the presence of its target protein using enzymatic digestion.
Julie Doucet, Alexandre Avrameas

J Pharm Biomed Anal· August 2010

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Reduction of matrix interferences by the combination of chaotropic salt and DMSO in a broadly applicable target-based ELISA for pharmacokinetic studies of therapeutic monoclonal antibodies.
Julie Doucet, Jasna Canadi, Christoph Kalis, Marie-Anne Valentin, Séverine Marrony, Alexandre Avrameas

J Pharm Biomed Anal· December 2009

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