Publications by authors named "Alexandre Bonet"

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Synthesis and evaluation of lipoic acid - donepezil hybrids for Alzheimer's disease using a straightforward strategy.
Vincent Luzet, Florentin Allemand, Chloé Richet, Barbara Dehecq, Alexandre Bonet

Bioorg Med Chem Lett· November 2024

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Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives.
Irene Pachón Angona, Helene Martin, Solene Daniel, Ignacio Moraleda, Alexandre Bonet

Int J Mol Sci· October 2020

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Design, Synthesis and Biological Evaluation of New Antioxidant and Neuroprotective Multitarget Directed Ligands Able to Block Calcium Channels.
Irene Pachòn Angona, Solene Daniel, Helene Martin, Alexandre Bonet, Artur Wnorowski

Molecules· March 2020

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New (benz)imidazolopyridino tacrines as nonhepatotoxic, cholinesterase inhibitors for Alzheimer disease.
Houssem Boulebd, Lhassane Ismaili, Helene Martin, Alexandre Bonet, Mourad Chioua

Future Med Chem· May 2017

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Synthesis and biological assessment of racemic benzochromenopyrimidinetriones as promising agents for Alzheimer's disease therapy.
Youssef Dgachi, Helène Martin, Alexandre Bonet, Mourad Chioua, Isabel Iriepa

Future Med Chem· May 2017

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Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapy.
Youssef Dgachi, Olga Sokolov, Vincent Luzet, Justyna Godyń, Dawid Panek, Alexandre Bonet

Eur J Med Chem· January 2017

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Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease.
Youssef Dgachi, Oscar M Bautista-Aguilera, Mohamed Benchekroun, Hélène Martin, Alexandre Bonet

Molecules· May 2016

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Imidazopyranotacrines as Non-Hepatotoxic, Selective Acetylcholinesterase Inhibitors, and Antioxidant Agents for Alzheimer's Disease Therapy.
Houssem Boulebd, Lhassane Ismaili, Manuela Bartolini, Abdelmalek Bouraiou, Vincenza Andrisano, Alexandre Bonet

Molecules· March 2016

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Inter-laboratory evaluation of the response of primary human hepatocyte cultures to model CYP inducers - a European Centre for Validation of Alternative Methods (ECVAM) - funded pre-validation study.
Lysiane Richert, Catherine Abadie, Alexandre Bonet, Bruno Heyd, Georges Mantion

Toxicol In Vitro· February 2010

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Effects of Andrographis paniculata extract and Andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo administration to rats and in vitro in rat and human hepatocyte cultures.
Dumrongsak Pekthong, Nadège Blanchard, Catherine Abadie, Alexandre Bonet, Bruno Heyd

Chem Biol Interact· May 2009

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Effects of long-term dietary intake of magnesium on oxidative stress, apoptosis and ageing in rat liver.
Hélène Martin, Béatrice Uring-Lambert, Markus Adrian, Abdeslam Lahlou, Alexandre Bonet

Magnes Res· June 2008

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Species differences in the response of liver drug-metabolizing enzymes to (S)-4-O-tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric acid (EMD 392949) in vivo and in vitro.
Lysiane Richert, Gregor Tuschl, Catherine Viollon-Abadie, Nadège Blanchard, Alexandre Bonet

Drug Metab Dispos· April 2008

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Effect of chrysin and natural coumarins on UGT1A1 and 1A6 activities in rat and human hepatocytes in primary culture.
Amina Chlouchi, Corinne Girard, Alexandre Bonet, Catherine Viollon-Abadie, Bruno Heyd

Planta Med· July 2007

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