Publications by authors named "Alexandre Chigaev"

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CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity.
Julia C Gutjahr, Elisabeth Bayer, Xiaobing Yu, Julia M Laufer, Jan P Höpner, Alexandre Chigaev

Haematologica· August 2021

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RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia.
Filip Matthijssens, Nitesh D Sharma, Monique Nysus, Christian K Nickl, Huining Kang, Alexandre Chigaev

J Clin Invest· March 2021

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Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity.
Dominique R Perez, Larry A Sklar, Alexandre Chigaev, Ksenia Matlawska-Wasowska

Semin Cancer Biol· January 2021

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TCL1 transgenic mice as a model for CD49d-high chronic lymphocytic leukemia.
Eva Szenes, Andrea Härzschel, Sarah Decker, Erika Tissino, Justine Pischeli, Alexandre Chigaev

Leukemia· September 2020

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Clioquinol: To harm or heal.
Dominique R Perez, Larry A Sklar, Alexandre Chigaev

Pharmacol Ther· July 2019

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High-Throughput Flow Cytometry Identifies Small-Molecule Inhibitors for Drug Repurposing in T-ALL.
Dominique R Perez, Christian K Nickl, Anna Waller, Cristina Delgado-Martin, Travis Woods, Alexandre Chigaev

SLAS Discov· August 2018

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High-Throughput Flow Cytometry Drug Combination Discovery with Novel Synergy Analysis Software, SynScreen.
Dominique R Perez, Bruce S Edwards, Larry A Sklar, Alexandre Chigaev

SLAS Discov· August 2018

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Evaluating integrin activation with time-resolved flow cytometry.
Jesus Sambrano, Alexandre Chigaev, Kapil S Nichani, Yelena Smagley, Larry A Sklar

J Biomed Opt· July 2018

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Functional and clinical relevance of VLA-4 (CD49d/CD29) in ibrutinib-treated chronic lymphocytic leukemia.
Erika Tissino, Dania Benedetti, Sarah E M Herman, Elisa Ten Hacken, Inhye E Ahn, Alexandre Chigaev

J Exp Med· February 2018

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A High-Throughput Flow Cytometry Assay for Identification of Inhibitors of 3',5'-Cyclic Adenosine Monophosphate Efflux.
Dominique Perez, Peter C Simons, Yelena Smagley, Larry A Sklar, Alexandre Chigaev

Methods Mol Biol· December 2017

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Relationship of light scatter change and Cdc42-regulated actin status.
Lin Hong, Stephanie Chavez, Yelena Smagley, Alexandre Chigaev, Larry A Sklar

Cytometry B Clin Cytom· November 2016

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Ibrutinib Inhibits VLA-4-Dependent Adhesion in CLL-Letter.
Antonella Zucchetto, Erika Tissino, Tanja Nicole Hartmann, Alexandre Chigaev, Giovanni Del Poeta

Clin Cancer Res· July 2016

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Cyclic AMP efflux inhibitors as potential therapeutic agents for leukemia.
Dominique R Perez, Yelena Smagley, Matthew Garcia, Mark B Carter, Annette Evangelisti, Alexandre Chigaev

Oncotarget· June 2016

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Does aberrant membrane transport contribute to poor outcome in adult acute myeloid leukemia?
Alexandre Chigaev

Front Pharmacol· July 2015

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The evaluation of thioridazine as a hematopoietic progenitor cell mobilizing agent in healthy human subjects.
Alexandre Chigaev, Larry A Sklar, Ronald Schrader, Nicole Stephens, Hengameh Raissy

J Clin Pharmacol· May 2015

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CXCL12-induced VLA-4 activation is impaired in trisomy 12 chronic lymphocytic leukemia cells: a role for CCL21.
Sylvia Ganghammer, Evelyn Hutterer, Elisabeth Hinterseer, Gabriele Brachtl, Daniela Asslaber, Alexandre Chigaev

Oncotarget· May 2015

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FRET detection of lymphocyte function-associated antigen-1 conformational extension.
Alexandre Chigaev, Yelena Smagley, Mark K Haynes, Oleg Ursu, Cristian G Bologa

Mol Biol Cell· January 2015

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Carbon monoxide down-regulates α4β1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization.
Alexandre Chigaev, Yelena Smagley, Larry A Sklar

BMC Immunol· October 2014

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Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.
Lin Hong, S Ray Kenney, Genevieve K Phillips, Denise Simpson, Chad E Schroeder, Alexandre Chigaev

J Biol Chem· March 2013

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Aspects of VLA-4 and LFA-1 regulation that may contribute to rolling and firm adhesion.
Alexandre Chigaev, Larry A Sklar

Front Immunol· August 2012

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Overview: assays for studying integrin-dependent cell adhesion.
Alexandre Chigaev, Larry A Sklar

Methods Mol Biol· January 2012

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Is prolonged stem cell mobilization detrimental for hematopoiesis?
Alexandre Chigaev, Stuart S Winter, Larry A Sklar

Med Hypotheses· December 2011

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Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion.
Alexandre Chigaev, Yelena Smagley, Larry A Sklar

BMC Immunol· May 2011

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A miniature Couette to generate shear for flow cytometry: studying real-time modulation of intracellular calcium in monocytic cells.
Gordon J Zwartz, Alexandre Chigaev, Terry D Foutz, Bruce Edwards, Larry A Sklar

Cytometry A· March 2011

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Drug Repurposing from an Academic Perspective.
Tudor I Oprea, Julie E Bauman, Cristian G Bologa, Tione Buranda, Alexandre Chigaev

Drug Discov Today Ther Strateg· January 2011

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