Publications by authors named "Alexandre Detappe"

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Inverse Correlation between Endoplasmic Reticulum Stress Intensity and Antitumor Immune Response with Ruthenium(II)-Based Photosensitizers for the Photodynamic Therapy of Head and Neck Squamous Cell Carcinoma.
Chloé Thibaudeau, Cyril Bour, Matthieu Scarpi-Luttenauer, Pierre Mesdom, Johannes Karges, Alexandre Detappe

J Med Chem· December 2025

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A Modular Supramolecular Peptide Platform Reveals Atomic-Number-Dependent Mechanisms Driving Radioenhancement.
Sebastian Jung, Pedro Lopez Navarro, Elsa Barbé, Adeline Gasser, Jolie Bou-Gharios, Alexandre Detappe

ACS Nano· December 2025

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Nanomaterials Trigger Functional Anti-Tumoral Responses in Primary Human Immune Cells.
Vincent Mittelheisser, Olivier Lefebvre, Mainak Banerjee, Shayamita Ghosh, Amandine Dupas, Alexandre Detappe

Adv Sci (Weinh)· October 2025

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Reinforced Polymer-Nanoparticle Hydrogels for Subcutaneous and Sustained Delivery of Trastuzumab.
Giovanni Bovone, Stéphane Bernhard, Guillaume Jacquot, Vincent Mittelheisser, Céline Mirjolet, Alexandre Detappe

Adv Healthc Mater· July 2025

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Comparative Preclinical Evaluation of Tuznue Versus Referent Herceptin: A Registered Trastuzumab Biosimilar.
Herve Bischoff, Neil K O'Connor, Jamie Kim, Bogdan V Popescu, Cecile Bigot, Alexandre Detappe

Drugs R D· March 2025

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Spacer engineering in nanoparticle-peptide conjugates boosts targeting specificity for tumor-associated antigens.
María de Los Angeles Ramírez, Jolie Bou-Gharios, Barbara Freis, Julien Draussin, Clémence Cheignon, Alexandre Detappe

Nanoscale· February 2025

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Antibody-Vincristine Conjugates as Potent Anticancer Therapeutic Agents.
Agathe Boos, Julien Most, Héloïse Cahuzac, Louis Moreira da Silva, François Daubeuf, Alexandre Detappe

J Med Chem· January 2025

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Chemical Production of Cytotoxic Bispecific Antibodies Using the Ugi Multicomponent Reaction.
Valentine Vaur, Ilias Koutsopetras, Stéphane Erb, Bianka Jackowska, Rania Benazza, Alexandre Detappe

Chembiochem· October 2024

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Landscape of Subcutaneous Administration Strategies for Monoclonal Antibodies in Oncology.
Guillaume Jacquot, Pedro Lopez Navarro, Coralie Grange, Lotfi Boudali, Sébastien Harlepp, Alexandre Detappe

Adv Mater· October 2024

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Supramolecular Heterodimer Peptides Assembly for Nanoparticles Functionalization.
Clélia Mathieu, Shayamita Ghosh, Julien Draussin, Adeline Gasser, Guillaume Jacquot, Alexandre Detappe

Adv Healthc Mater· June 2024

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Corrigendum to "Corrigendum to 'Advanced multimodal nanoparticles delay tumor progression with clinical radiation therapy' [Journal of Controlled Release 238 (2016) 103-133]" [Journal of Controlled Release (year) Volume 329 (2021) Pages 1283-1285].
Alexandre Detappe, Sijumon Kunjachan, Lucie Sancey, Vincent Motto-Ros, Douglas Biancur

J Control Release· June 2024

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Site-Selective Protein Conjugation by a Multicomponent Ugi Reaction.
Ilias Koutsopetras, Valentine Vaur, Rania Benazza, Hélène Diemer, Charlotte Sornay, Alexandre Detappe

Chemistry· March 2024

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Subcutaneous Administration of a Zwitterionic Chitosan-Based Hydrogel for Controlled Spatiotemporal Release of Monoclonal Antibodies.
Thomas Gréa, Guillaume Jacquot, Arthur Durand, Clélia Mathieu, Adeline Gasser, Alexandre Detappe

Adv Mater· March 2024

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Influence of pneumatic transportation on the stability of monoclonal antibodies.
Pierre Coliat, Stéphane Erb, Hélène Diemer, Dan Karouby, Tristan Martin, Alexandre Detappe

Sci Rep· December 2023

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Author Correction: Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma.
Alexandre Detappe, Hung V-T Nguyen, Yivan Jiang, Michael P Agius, Wencong Wang

Nat Nanotechnol· September 2023

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An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Gaofeng Cui, Maria Victoria Botuyan, Pascal Drané, Qi Hu, Benoît Bragantini, Alexandre Detappe

Nat Commun· September 2023

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An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Gaofeng Cui, Maria Victoria Botuyan, Pascal Drané, Qi Hu, Benoît Bragantini, Alexandre Detappe

bioRxiv· July 2023

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Author Correction: Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma.
Alexandre Detappe, Hung V-T Nguyen, Yivan Jiang, Michael P Agius, Wencong Wang

Nat Nanotechnol· April 2023

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Clinically Translatable Transcrocetin Delivery Platform for Correction of Tumor Hypoxia and Enhancement of Radiation Therapy Effects.
Marie-Charlotte Diringer, Pierre Coliat, Clélia Mathieu, Nina Laurent, Carole Mura, Alexandre Detappe

Small· March 2023

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Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma.
Alexandre Detappe, Hung V-T Nguyen, Yivan Jiang, Michael P Agius, Wencong Wang

Nat Nanotechnol· February 2023

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Retraction of: "Nanoparticle Mediated Tumor Vascular Disruption: A Novel Strategy in Radiation Therapy".
Sijumon Kunjachan, Alexandre Detappe, Rajiv Kumar, Thomas Ireland, Lisa Cameron

Nano Lett· November 2022

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A Combination of Native LC-MS Approaches for the Comprehensive Characterization of the Antibody-Drug Conjugate Trastuzumab Deruxtecan.
Evolène Deslignière, Hélène Diemer, Stéphane Erb, Pierre Coliat, Xavier Pivot, Alexandre Detappe

Front Biosci (Landmark Ed)· October 2022

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Retraction Note: Selective Priming of Tumor Blood Vessels by Radiation Therapy Enhances Nanodrug Delivery.
Sijumon Kunjachan, Shady Kotb, Robert Pola, Michal Pechar, Rajiv Kumar, Alexandre Detappe

Sci Rep· August 2022

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Optimal Physicochemical Properties of Antibody-Nanoparticle Conjugates for Improved Tumor Targeting.
Vincent Mittelheisser, Pierre Coliat, Eric Moeglin, Lilian Goepp, Jacky G Goetz, Alexandre Detappe

Adv Mater· June 2022

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Anti-BCMA Immuno-NanoPET Radiotracers for Improved Detection of Multiple Myeloma.
Eloise Thomas, Clélia Mathieu, Patricia Moreno-Gaona, Vincent Mittelheisser, François Lux, Alexandre Detappe

Adv Healthc Mater· January 2022

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