Publications by authors named "Alexandre Evrard"

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Genetic polymorphisms of and genes are associated with exposure to sunitinib and cardiovascular toxicity.
Litaty C Mbatchi, Fanny Leenhardt, Bob-Valéry Occean, Olivier Perrin, Jean-Christophe Boyer, Alexandre Evrard

Pharmacogenomics· November 2025

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French-Speaking Network of Pharmacogenetics (RNPGx) Recommendations for Clinical Use of Mavacamten.
Louis Lebreton, Jean-Christophe Boyer, Claire Lafay-Chebassier, Benjamin Hennart, Sarah Baklouti, Alexandre Evrard

Clin Pharmacol Ther· February 2025

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ATR inhibition potentiates FOLFIRINOX cytotoxic effect in models of pancreatic ductal adenocarcinoma by remodelling the tumour microenvironment.
Marine Bruciamacchie, Véronique Garambois, Nadia Vie, Thomas Bessede, Henri-Alexandre Michaud, Alexandre Evrard

Br J Cancer· February 2025

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High BRAF V600 Mutation Level Associated with Worse Outcome in Metastatic Melanoma Patients Receiving BRAF and MEK Inhibitors.
Ariane Fizazi, Chris Serrand, Alexandre Evrard, Blanche Bergeret, Pierre-Emmanuel Stoebner

Acta Derm Venereol· November 2024

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Regorafenib plus FOLFIRINOX as first-line treatment for patients with RAS-mutant metastatic colorectal cancer (FOLFIRINOX-R trial): a dose-escalation study.
Antoine Adenis, François Ghiringhelli, Ludovic Gauthier, Thibault Mazard, Ludovic Evesque, Alexandre Evrard

Cancer Chemother Pharmacol· September 2024

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Identification of non-adherence to adjuvant letrozole using a population pharmacokinetics approach in hormone receptor-positive breast cancer patients.
Alicja Puszkiel, Florence Dalenc, Naïma Tafzi, Pierre Marquet, Marc Debled, Alexandre Evrard

Eur J Pharm Sci· August 2024

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[Unusual association of BRAF and MEK inhibitors: Clinical response of metastatic melanoma treated with dabrafenib-cobimetinib].
Fanny Leenhardt, Litaty Mbatchi, Alexandre Evrard, Didier Cupissol, Candice Lesage

Bull Cancer· June 2023

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Combining Three Tyrosine Kinase Inhibitors: Drug Monitoring Is the Key.
Quentin Dominique Thomas, Nelly Firmin, Litaty Mbatchi, Alexandre Evrard, Xavier Quantin

Int J Mol Sci· March 2023

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Pharmacokinetic Variability Drives Palbociclib-Induced Neutropenia in Metastatic Breast Cancer Patients: Drug-Drug Interactions Are the Usual Suspects.
Fanny Leenhardt, Frédéric Fiteni, Ludovic Gauthier, Marie Alexandre, Séverine Guiu, Alexandre Evrard

Pharmaceutics· April 2022

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Impact of pharmacist consultation at clinical trial inclusion: an effective way to reduce drug-drug interactions with oral targeted therapy.
Fanny Leenhardt, Marie Alexandre, Severine Guiu, Stephane Pouderoux, Melanie Beaujouin, Alexandre Evrard

Cancer Chemother Pharmacol· October 2021

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Therapeutic Bayesian monitoring of sunitinib in two patients with impaired absorption or elimination.
Fanny Leenhardt, Marie Viala, Diego Tosi, Emmanuelle Samalin-Scalzi, Alexandre Evrard

J Clin Pharm Ther· August 2021

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Population pharmacokinetic model of irinotecan and its four main metabolites in patients treated with FOLFIRI or FOLFIRINOX regimen.
Laure Deyme, Dominique Barbolosi, Litaty Céphanoée Mbatchi, Nicole Tubiana-Mathieu, Marc Ychou, Alexandre Evrard

Cancer Chemother Pharmacol· August 2021

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PXR Modulates the Prostate Cancer Cell Response to Afatinib by Regulating the Expression of the Monocarboxylate Transporter SLC16A1.
Alice Matheux, Matthieu Gassiot, Gaëlle Fromont, Fanny Leenhardt, Abdelhay Boulahtouf, Alexandre Evrard

Cancers (Basel)· July 2021

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Model-Based Quantification of Impact of Genetic Polymorphisms and Co-Medications on Pharmacokinetics of Tamoxifen and Six Metabolites in Breast Cancer.
Alicja Puszkiel, Cécile Arellano, Christelle Vachoux, Alexandre Evrard, Valérie Le Morvan

Clin Pharmacol Ther· May 2021

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Vancomycin Serum Concentration after 48 h of Administration: A 3-Years Survey in an Intensive Care Unit.
Nicolas Perin, Claire Roger, Grégory Marin, Nicolas Molinari, Alexandre Evrard

Antibiotics (Basel)· November 2020

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Cancer Immunotherapy Dosing: A Pharmacokinetic/Pharmacodynamic Perspective.
Félicien Le Louedec, Fanny Leenhardt, Clémence Marin, Étienne Chatelut, Alexandre Evrard

Vaccines (Basel)· October 2020

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Liquid chromatography-tandem mass spectrometric assay for the quantification of CDK4/6 inhibitors in human plasma in a clinical context of drug-drug interaction.
Fanny Leenhardt, Matthieu Gracia, Catherine Perrin, Claudia Muracciole-Bich, Bénédicte Marion, Alexandre Evrard

J Pharm Biomed Anal· September 2020

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The Anti-Cancer Drug Dabrafenib Is a Potent Activator of the Human Pregnane X Receptor.
Nicolas Creusot, Matthieu Gassiot, Elina Alaterre, Barbara Chiavarina, Marina Grimaldi, Alexandre Evrard

Cells· July 2020

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Pharmacogenetics and pharmacokinetics modeling of unexpected and extremely severe toxicities after sorafenib intake.
Hai le Ba, Litaty Mbatchi, Florence Gattacceca, Alexandre Evrard, Bruno Lacarelle

Pharmacogenomics· February 2020

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Factors Affecting Tamoxifen Metabolism in Patients With Breast Cancer: Preliminary Results of the French PHACS Study.
Alicja Puszkiel, Cécile Arellano, Christelle Vachoux, Alexandre Evrard, Valérie Le Morvan

Clin Pharmacol Ther· September 2019

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Probing Quantum Criticality and Symmetry Breaking at the Microscopic Level.
Vasiliy Makhalov, Tanish Satoor, Alexandre Evrard, Thomas Chalopin, Raphael Lopes

Phys Rev Lett· September 2019

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Persistent response to vemurafenib in metastatic ameloblastoma with BRAF mutation: a case report.
Morgane Broudic-Guibert, Jean-Yves Blay, Léa Vazquez, Alexandre Evrard, Marie Karanian

J Med Case Rep· July 2019

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Enhanced Magnetic Sensitivity with Non-Gaussian Quantum Fluctuations.
Alexandre Evrard, Vasiliy Makhalov, Thomas Chalopin, Leonid A Sidorenkov, Jean Dalibard

Phys Rev Lett· May 2019

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Toxicity and pharmacokinetic profile of SGM-101, a fluorescent anti-CEA chimeric antibody for fluorescence imaging of tumors in patients.
Bérénice Framery, Marian Gutowski, Karen Dumas, Alexandre Evrard, Nathalie Muller

Toxicol Rep· April 2019

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