Publications by authors named "Alexandre Lemire"

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Discovery of Potent, Selective, and Orally Available IRE1α Inhibitors Demonstrating Comparable PD Modulation to IRE1 Knockdown in a Multiple Myeloma Model.
Marie-Gabrielle Braun, Avi Ashkenazi, Ramsay E Beveridge, Georgette Castanedo, Heidi Ackerly Wallweber, Alexandre Lemire

J Med Chem· June 2024

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Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1α Inhibitory Activity.
Ramsay E Beveridge, Heidi Ackerly Wallweber, Avi Ashkenazi, Maureen Beresini, Kevin R Clark, Alexandre Lemire

ACS Med Chem Lett· December 2020

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Stereoselective syntheses of L-pipecolic acid and (2S,3S)-3-hydroxypipecolic acid from a chiral N-imino-2-phenyl-1,2-dihydropyridine intermediate.
Alexandre Lemire, André B Charette

J Org Chem· March 2010

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Total synthesis and biological evaluation of (+)- and (-)-bisanthraquinone antibiotic BE-43472B and related compounds.
K C Nicolaou, Jochen Becker, Yee Hwee Lim, Alexandre Lemire, Thomas Neubauer

J Am Chem Soc· October 2009

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Stereoselective synthesis of 2,6-disubstituted 3-piperidinols: application to the expedient synthesis of (+)-julifloridine.
Alexandre Lemire, André B Charette

Org Lett· June 2005

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[4+2] Cycloaddition of 2-substituted 1,2-dihydropyridines with nitrosobenzene: asymmetric synthesis of trans-2-substituted 3-amino-1,2,3,6-tetrahydropyridines.
Alexandre Lemire, Daniel Beaudoin, Michel Grenon, André B Charette

J Org Chem· March 2005

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Nucleophilic addition to 3-substituted pyridinium salts: expedient syntheses of (-)-L-733,061 and (-)-CP-99,994.
Alexandre Lemire, Michel Grenon, Mehrnaz Pourashraf, André B Charette

Org Lett· September 2004

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